MOA by class Flashcards
1
Q
Penicillins MOA
A
Bind PBP- inhibit crosslinking
2
Q
aminoglycosides MOA
A
Irreversibly bind 30S - inhibit protein synthesis
3
Q
cephalosporins MOA
A
bind PBP - inhibit crosslinking
4
Q
Monobactam MOA
A
Binds PBP-3 - inhibits crosslinking
5
Q
glycopeptides MOA
A
bind D-ala D-ala
6
Q
oxazolidinones MOA
A
bind 50S
7
Q
carbapenems MOA
A
bind PBP-2
8
Q
lipopeptides (daptomycin) MOA
A
membrane depolarization - inhibits DNA and protein synthesis
9
Q
tetracyclines MOA
A
reversibily bind 30S
10
Q
TMP-SMX MOA
A
inhibits PABA pathway - inhibits purine synthesis
11
Q
fluoroquinolones MOA
A
inhibits topoisomerases II (DNA gyrase) and topoisomerase IV
12
Q
metronizole MOA
A
inhibits DNA synthesis in Anaerobes
13
Q
clindamycin MOA
A
Binds 50S
14
Q
macrolides MOA
A
Bind 50S
15
Q
streptogramins MOA
A
bind 50S
