MOA Flashcards
MOA MEGLITINIDES
SOA
MOA- stimulate insulin secretion from beta cells
SOA PANCREAS
MOA BIGUANIDES
SOA
MOA decrease glucose output from the liver
Increase peripheral muscle uptake
SOA LIVER AND PERIPHERAL MUSCLE
MOA THIAZOLIDINEDIONES
SOA
MOA INCREASE PERIPHERAL MUSCLE UPTAKE
slight decrease in glucose output from liver
SOA MUSCLE AND ADIPOSE TISSUE
MOA ALPHA GLUCOSIDASE INHIBITORS
SOA
MOA decrease breakdown of sucrose and complex carbs into small intestine (reduce the rate of digestion and absorption of glucose
SOA GUT
MOA GLIPTIN (DPP4 inhibitors)
MOA increase effects of incretin (reduce food intake, promote insulin secretion, slow gastric emptying, decrease glucagon secretion)
MOA SGLT2
SOA
MOA Inhibit SGLT2 to increase glucose secretion
SOA PROXIMAL TUBULES
MOA SULFONYLUREAS
SITE OF ACTION
MOA- stimulate beta cells to release insulin
Soa- pancreas