MOA Flashcards

1
Q

MOA MEGLITINIDES

SOA

A

MOA- stimulate insulin secretion from beta cells

SOA PANCREAS

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2
Q

MOA BIGUANIDES

SOA

A

MOA decrease glucose output from the liver
Increase peripheral muscle uptake

SOA LIVER AND PERIPHERAL MUSCLE

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3
Q

MOA THIAZOLIDINEDIONES

SOA

A

MOA INCREASE PERIPHERAL MUSCLE UPTAKE
slight decrease in glucose output from liver

SOA MUSCLE AND ADIPOSE TISSUE

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4
Q

MOA ALPHA GLUCOSIDASE INHIBITORS

SOA

A

MOA decrease breakdown of sucrose and complex carbs into small intestine (reduce the rate of digestion and absorption of glucose

SOA GUT

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5
Q

MOA GLIPTIN (DPP4 inhibitors)

A

MOA increase effects of incretin (reduce food intake, promote insulin secretion, slow gastric emptying, decrease glucagon secretion)

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6
Q

MOA SGLT2

SOA

A

MOA Inhibit SGLT2 to increase glucose secretion

SOA PROXIMAL TUBULES

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7
Q

MOA SULFONYLUREAS

SITE OF ACTION

A

MOA- stimulate beta cells to release insulin

Soa- pancreas

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