MNT for Liver Flashcards
The liver has over ____ functions
500
Manufactures blood proteins
Rough ER
Produce bile salts and detoxifies blood-borne poisons
Smooth ER
Detoxify other poisons, including alcohol
Peroxisomes
Supplies energy
Mitochondria
Packages
Golgi apparatus
Stores sugar and regulates blood glucose levels
Glycosomes
Produce ____ - _____ mL bile each day
500-1000
Regeneration capacity is done through:
Liver stem cells
Liver manufactures
Protein
Glycogen
Bile
Cholesterol
Liver stores
Iron
Fat-soluble vitamins
Glycogen
Liver wastes
Ammonia
Drugs and alcohol
Bilirubin
Bacteria
Diseases of the liver
Hepatitis - acute viral, fulminant, chronic
Alcoholic liver disease, alcoholic hepatitis, and cirrhosis
NASH
Cholestatic liver disease (primary biliary cirrhosis, cholangitis)
Inherited disorders
Other liver diseases
Features similar to acute hepatitis but with more severe liver damage and serious clinical state
Acute liver failure
Present in acute liver failure but not in acute hepatitis
Encephalopathy
Poor coagulation
Hepatic atrophy
Brain edema
High risk of death without transplant
Hallmark of infection
HBsAg
Acute infection (serological marker)
Anti-HBc IgM
Resolved infection (serological marker)
Anti-HBc total
High viral load and high infectivity
HBeAg
Antibody to HBeAg, indicates decreasing HBV DNA
Anti-HBe
Recovery from acute infection
Anti-HBs
Widespread inflammation of the liver caused by hepatitis viruses A, B, C, D, and E
Acute hepatitis
Hepatitis A:
Oral and fecal route
Hepatitis B and C:
Body fluids
Hepatitis D
Occurs only in parts with B
Hepatitis E:
Oral fecal route, most seen in Asia, Africa, and Mexico
4 phases of symptoms
Prodromal
Pre-icteric
Icteric
Convalescent
Malaise, fatigue, low-grade fever, nausea vomiting, aversion to food, mild itching, joint/muscle pain
Prodromal
Icteric
Yellow eyes, dark urine, light stool
Gradual recovery
Convalescent