Mnemonics Flashcards
Live attenuated Vaccines
LIVE! one night only! see SMALL YELLOW ROTATING CHICKENS get vaccinated with SABIN AND MMR! IT’S INcredible .
Live attenuated: Small pox, Yellow fever, Rotavirus, Chickenpox, Sabin polio, MMR, Influenza (intranasal)
Killed Vaccines
SalK=Killed
RIP Always
Rabies, Influenza, Salk Polio and HAV vaccines
Positive Stranded RNA Viruses
I went to a RETRO TOGA party where I drank FLAVored CORONA and ate HIPPY CALIFORNIA PICKLES
retrovirus, togavirus, flavivirus, coronavirus, hepevirus, calcivirus, picornavirus
Segmented Viruses
BOAR
Bunyavirus, Orthomyxovirus, Arenavirus, Reovirus
Amoxicillin and ampicillin clinical use-extended spectrum
ampicillin/amoxicillin HHELPSS kill enterococci
H.influenzae, H.pylori, E.Coli, Listeria, Proteus, Salmonella, Shigella
Organisms typically not covered by cephalosporins
Organisms typically not covered by cephalosporins are LAME
Listeria, Atypicals (chlamydia, mycoplasma), MRSA, Enterococci (except Ceftaroline covers MRSA)
2nd generation cephalosporins
2nd generation-HEN PEcKS and gram positive cocci
Haemophilus, Enterobacter, Neisseria, Proteus, E.Coli, Klebseilla, Serratia
Macrolides Toxicity
MACRO
gastrointestinal MOTILITY issues, ARRYTHMIAS caused by prolonged QT, acute CHOLESTATIC hepatitis, RASH, eOSINOPHILIA, also inhibit cytochrome p450 (except azithromycin)
Genes for 5 bacterial toxins encoded in a lysogenic phage
Form of specialized transduction in bacterial genetics
ABCDE
shigA like toxin Botulinum toxin Cholera toxin Diphteria toxin Erythrogenic toxin of Streptococcus pyogenes
Antibiotics to avoid in pregnancy
SAFe Children Take Really Good Care
Sulfonamides-kernicterus Aminoglycosides-ototoxicity Fluroquinolones-cartilage damage Clarithromycin-embryotoxic Tetracyclines-teeth discoloration, inhibition bone growth Ribavirin-teratogen Griseofulvin-teratogen Chloramphenicol-grey baby syndrome
Causes of eosinophilia
NAACP
Neoplasia Asthma Allergies Chronic adrenal insufficiency Parasites (invasive)
Pathology Associated with Target Cells
HALT said the hunter to his target
HbC disease
Asplenia
Liver disease
Thalassemia
LEAD
Lead Lines on gingiva (burton’s line) and metaphyses of long bone on x ray
Encephalopathy and Erythrocyte basophilic stippling
Abdoinal colic and sideroblastic Anemia
Drops-wrist and foot drop. Dimercaprol and eDTA=1st line tx
Iron chelation for kids
Succimer
It sucks to be a kid who eats lead
Autoimmune Hemolytic Anemias
Warm Agglutinin and Cold Agglutinin
Warm weather is Great; Warm agglutinin (IgG)
Cold weather is MMMiserable; Cold Agglutinin (IgM)
Acute Intermittent Porphyria presenting symptoms
5 P’s
Painful abdomen Polyneuropathy Port wine colored urine Psychological disturbances Precipitated by drugs
Multiple Myeloma Symptoms
CRAB
hyperCalcemia
Renal involvement
Anemia
Bone lytic lesions/Back pain
Causes of High Anion Gap Metabolic Acidosis
Anion Gap=Sodium- (Chloride + Bicarbonate)
MUDPILES Methanol Uremia Diabetic Ketoacidosis Propylene glycol, Paraldehyde Isoniazid/Iron Lactic Acidosis Ethylene Glycol (antifreeze) Salicylates (aspirin)
Post splenectomy there is higher risk of which encapsulated organisms?
decreased IgM-decreased complement activation-decreased opsonization=increased susceptibility to encapsulated organisms
SHiNE SKiS Streptococcus pneumoniaie Haemophilus influenza type B Neisseria meningitidis E. Coli Salmonella spp Kleibsella pneumoniaie Group b Streptococcus
Para aortic Lymph Node
testes, ovaries, kidneys, uterus are area of body drained
Para TOKUt
Superior Mesenteric Lymph Node
Lower duodenum, jejunum, ileum, colon to splenic flexure
Superior DJ Ill messed up some colons and commas
Inferior Mesenteric Lymph Node
Colon from splenic flexure to upper rectum
Internal Iliac Lymph Node
Lower rectum to anal canal (above pectinate line), bladder, vagina (middle third), prostate
The Internist’s Silly dilemna: To read the LR annals (lower rectum to anal canal) which are above and beyond boring (above the pectinate line), or read the Blogs (Bladder) or watch the Vast Videos (Vagina) or listen to news from the Press (prostate)?
Superficial inguinal
Anal canal (below pectinate line), skin below umbilicus (except popliteal territory and glans of the penis), scrotum
The Superficial inguinal (superficial ingeniero) looked to cool off his inguinal skin regions before working on his projects, so he put: A C down below on his Skin below umbilicus & Scrotum
Seronegative Arthropathies
HLA B27
PAIR Psoriatic Arthritis Ankylosing Spondylitis arthritis of Inflammatory Bowel Disease Reactive arthritis (formerly known as Reiter syndrome)
Direct vs Indirect hernias in relation to the inferior epigastric artery
MDs don’t LIe
Medial to the inferior epigastric artery=Direct hernia
Lateral to the inferior epigastric artery=Indirect hernia
Passive Immunity after exposure (preformed antibodies given)
To Be Healed Very Rapidly Tetanus toxin Botulinum toxin HBV Varicella Rabies virus
Chronic Granulomatous Disease-increased susceptibility to catalase + organisms
Need PLACESS Nocardia Pseudomonoas Listeria Aspergillus Candida E.Coli S.Aureus Serratia and Burkholderia cepacia
Psammoma bodies
PSaMMoma Papillary carcinoma of thyroid Serous papillary cystadenocarcinoma of ovary Meningioma Malignant mesothelioma
Example Drugs with Zero Order Elimination
PEA round like a 0 in zero order
Phenytoin
Ethanol
Aspirin
Bethanechol
Bethany, call (Bethanechol) me to activate your Bowels and Bladder
Activates bowel and bladder smooth muscle
Pilocarpine
You cry, drool, and sweat on your PILOw
Potent stimulator of sweat, tears, and saliva
Neostigmine
Neo CNS=NO CNS penetration
Physostigmine
Physostigmine “phyxes” atropine overdose
Pyridostigmine
PyRIDostiGMine gets RID of Myasthenia Gravis
Cholinesterase inhibitor poisoning
DUMBBELSS
diarrhea, urination, miosis, bradycardia, bronchospasm, excitation of skeletal muscle, lacrimation, salivation, sweating
Benztropine use
Park my Benz
Parkinson disease and acute dystonia
Tetrodotoxin
puffer fish, binds fast voltage gated Na channels in cardiac and nerve tissue and prevent depolarization
paresthesia, weakness, dizziness, loss of reflexes
Ciguatoxin
Reef fish (barracuda, snapper, moray eel)
Open Na channels cause depolarization
confused with cholinergic poisoning
Temperature related dyesthesis (cold feel hot;hot feels cold)
Scombroid Poisoning
Dark meat fish (bonito, mackerel, mahi mani, tuna)-improperly stored. Histamine issue-not degraded by cooking
Anaphylaxis like presentation
Hyperglycemia drug reaction
Taking Pills Necessitates Having blood Sugar Checked
Tacrolimus Protease inhibitors Niacin HCTZ Corticosteroids
Diarrhea Drug reaction
Might Excite Colon On Accident Metformin Erythromycin Colchicine Orlistat0 Acarbose
Focal to massive hepatic necrosis drug reaction
Liver "HAVAc" Halothane Amanita phalloides (death cap mushroom) Valproic acid Acetaminophen
Pancreatitis Drug reaction
Drugs Causing A Violent Abdominal Distress Didanosine Corticosteroids Alcohol Valproic acid Azathioprine Diuretics
Agranulocytosis drug reaction
Gangs CCCrush Myeloblasts and Promyelocytes Ganciclovir Clozapine Carbamezepine Colchicine Methimazole Propylthiouracil
Aplastic Anemia drug reaction
Can't Make New Blood Cells Properly Carbamezapine Methimazole NSAIDS Benzene Chloramphenicol Propylthiouracil
Hemolysis in G6PD deficiency drug reaction
Hemolysis IS D PAIN Isoniazid Sulfonamides Dapsone Primaquine Aspirin Ibuprofen Nitrofurantoin
Megaloblastic anemia drug reaction
having a Blast with PMS
Phenytoin
Methotrexate
Sulfa drugs
Fat redistribution drug reaction
Fat PiG
Protease inhibitors
Glucocorticoids
Hyperuricemia drug reaction
Painful Tophi and Feet Need Care Pyrazinamide Thiazides Furosemide Niacin Cyclosporine
Photosensitivity drug reaction
SAT For Photo Sulfonamides Amiodarone Tetracyclines 5FU
Seizures drug reaction
with seizures, I BItE my tongue Isoniazid (vitamin b6deficiency) Buproprion Imipenem/cilastatin Enflurane
SIADH drug reaction
Can’t Concentrate Serum Sodium
Carbamezapine
Cyclophosphamide
SSRIs
Pulmonary Fibrosis
Breathing Air Badly from Medications Bleomycin Amiodarone Busulfan Methotrexate
Cytochorome P450 inducers
Chronic alcoholics STeal Phen PHen and NEver Refuse GReasy Carbs
Chronic alcoholics St.John's Wort Phenytoin Phenobarbital Nevirapine Rifampin Griseofulvin Carbamezepine
Cytochrome P450 Inhibitors
AAA RACKS IN GQ Magazine acute alcohol abuse Ritonavir Amiodarone Cimetidine Ketoconazole Sulfonamides Isoniazid Grapefruit juice Quinidine Macrolides (except Azithromycin)
Sulfa Drugs
Popular FACTSSS about Sulfa Probenecid Furosemide Acetazolamide Celecoxib Thiazides Sulfonamide antibiotics Sulfasalazine Sulfonylureas
B1 selective antagonists
Selective antagonists go from A to M (B1 with 1st half of alphabet)
Acebutolol, atenolol, betaxolol, esmolol, metoprolol
Non selective antagonists
Nonselective antagonists go from N to Z (B2 with 2nd half of alphabet)
nadolol, pindolol (partial agonist), propranolol, timolol
Cutaneous flushing drug reaction
VANC vancomycin adenosine niacin calcium channel blockers
Right to Left Shunts
5 T’s
1) Truncus arteriosus (1 vessel)
2) Transposition (2 switched vessels)
3) Tricuspid atresia (3=Tri)
4) Tetralogy of Fallot (4=Tetra)
5) TAPVR (5 letters in the name)
Left to Right shunts
LaterR (Left to Right) shunts: LateR cyanosis
Right to Left shunts
eaRLy cyanosis (Right to Left shunts)
Relation of the pulmonary artery to the bronchus at each lung hilum
RALS
Right Anterior
Left Superior
Structures perforating the diaphraghm and spinal levels
T8: IVC
T10: Oesophagus and CN 10 (vagus)
T12: Aortic hiatus (aorta-red, thoracic duct-white, vein-blue) At T-1-2 it’s the red, white and blue
Structures perforating the diaphragm=T level
I ate ten eggs at twelve
I (IVC) ate (8) ten (10) eggs (esophagus) at (aorta) twelve (12)
Carotid Bifurcation
The common carotid biFOURcates at C4
Trachea Bifurcation
the trachea biFOURcates at T4
Abdominal aorta Bifurcation
the abdominal aorta biFOURcates at L4
Lung volumes
LITER Lung volumes IRV TV ERV RV
Determination of physiologic dead space equation-order of variables
Taco, Paco, Peco, Paco
Hemoglobin affinity for oxygen (taut vs relaxed)
Taut in Tissues (taut, deoxygenated, low affinity for oxygen-goes to tissues)
Relaxed in Respiratory tract (relaxed, oxygenated, high affinity for oxygen)
Autosomal Dominant
Hyper IgE syndrome
Job Syndrome
Can’t get to the Job site STAT
Stat 3 mutation-impaired recruitment of neutrophils to sites of infection
FATED coarse Facies cold (noninflamed) Staph. Abscesses retained primary TEETH Increased IgE Dermatologic problems
Gluconeogenesis Irreversible Enzymes
Pathway Produces Fresh Glucose
Pyruvate Carboxylase
Phosphoenolpyruvate carboxykinase
Fructose 1, 6 bisphosphatase
Glucose 6 Phosphatase
Pyruvate Dehydrogenase Complex Deficiency Treatment
Lysine and Leucine, the onLy pureLy ketogenic amino acids
also high fat diet
Pyruvate Dehydrogenase Complex Co factors (5 of them)
Same cofactors for Alpha ketoacid Dehydrogenase
Tender Loving Care For Nobody Thiamine;TPP;Pyrophosphate Lipoic acid CoA=panthothenic acid=B5 FAD (B2=riboflavin) NAD (B3-niacin)
Essential amino acids
Private (PVT) TIM HaLL Phenylalanie Valine Threonine Tryptophan Isoleucine Methionine Histidine Leucine Lycine
Cystinuria defect of PCT and intestinal amino acid transporter prevents reabsorption of:
COLA Cysteine Ornithine Lysine Arginine
Maple Syrup Urine Disease: blocked degradation of which branched amino acids
I Love Vermont maple syrup from maple trees with branches
Isoleucine
Leucine
Valine
Differential diagnosis for Eosinophilia
DNAAACP Drugs Neoplasm Atopic Disease Asthma Addison's disease Acute interstial nephritis Collagen vascular disease Parasites
Vitamin B2 (riboflavin)
FAD and FMN are derived from riboflavin
B2=2ATP
The 2 C’s of B2
Cheilosis
Corneal vascularization
Vitamin B3 (niacin)
NAD derived from Niacin (B3=3ATP) The 3 D's of B3 Dementia Diarrhea Dermatitis
Insulin Independent Glucose Uptake GLUT Transporters
BRICK L Brain RBCs Intestine Cornea Kidney Liver
Fetal Erythropoiesis
Young Liver Synthesizes Blood Yolk Sac Liver Spleen Bone Marrow
Potter Sequence/Syndrome
Baby's who can't Pee in utero develop Potter Sequence POTTER Pulmonary Hypoplasia Oligohydramnios (trigger) Twisted face Twisted Skin Extremity defects Renal failure (in utero)
Ureters course
Water (ureters) Under the bridget (uterine artery, vas deferens)
Ureters pass Under uterine artery and Under ductus deference (retroperitoneal)