MKSAP14 Flashcards
A flutter classically has an atrial rate of _________ and a ventricular rate of ______
300;150 i.e. 2:1
How is DAPT affected by history of stroke?
If pt has had ischemic stroke then cannot have prasugrel as it is contraindicated
What is the concern for a pt with COPD who has RAD/RBBB
May have cor pulmonale (WHO III pulmonary HTN)
How many PVCs make up VT? When is VT considered to be sustained?
more than 3 PVCs, if VT lasts >30 sec
In a pt with inferior MI, what is an indicator that the pt may have concomittant RV involvment?
Development of hypotension with the administration of SLNTG
In a pt who has had several heart surgeries who presents with elevated JVP, ascites, LE edema with normal LV systolic fxn the most likely dx is __________. What is the low-pitched early diastolic sound that can be heard?
Constrictive pericarditis (would need R heart cath); Pericardial Knock
What is the likely etiology of a pt with myocardial ischemia who has symmetric, deep TWIs in V2-V3 with flat ST segment?
Proximal LAD occlusion (Wellen Syndrome)
What should you think if a pt on digoxin develops atrial tachycardia with a 2:1 AV block?
Digoxin toxicity, increased risk if hypokalemic
What are signs of cardiac involvment with pts who have systemic sarcoidosis?
Development of AV block or bundle branch blocks and heart failure; tx with steroids; Dx often with Bx of something else as endomyocardial bx may be nl due to patchy distribution of granulomas
What is endomyocardial fibroelastosis? ARVC?
A restrictive cardiomyopathy seen predominately in West Africa; ARVC is infiltration of fibrofatty tissue into the RV; assoc. with plakoglobin gene mutation
What may be the etiology of a pt who has afib on digoxin who develops a junctional rhythm (no p waves but regular rhythm)?
Digoxin toxicity
Tx of a pt with frequent PVCs who develops cardiomyopathy __________
Catheter Ablation
A cardiac physical exam of a sustained apical impulse suggests _______
LVH
What is the efficacy of aldosterone antagonists in HFpEF?
No benefit per TOPCAT study
The classic presentation of RV infarction is what?
CP, distended neck veins, hypotension, and CLEAR LUNGS
What is the hemodynamic variable most likely to be elevated in RV infarction?
CVP as it is a measure of RA pressure; PCWP is measure of LA pressure
Possible etiology of refractory HTN in young woman?
Fibromuscular dysplasia causing renal artery stenosis
When is intervention needed in pulmonic stenosis?
Anytime that there is pulmonic stenosis, regardless of whether or not there are symptoms; usual Tx of choice is balloon valvuloplasty but NOT if there is dysplasia or if there is a concomittant regurgitation component
In what situation is an endomyocardial bx likely to be useful?
In a newly diagnosed acute heart failure exacerbation that is associated with conduction abnormalities (AV block) and ventricular tachyarrhythmias to look for giant cell myocarditis (can add steroids)
What is the concern for a pt with acute CP and sx of CHF who has a mechanic AV?
Valve thrombosis i.e. INR is 1.6; it basically can lead to obstructive shock type picture
What findings are consistent with an acute posterior MI on EKG?
Prominent R waves with ST depression in the septal and anterior precordial leads V1-V3); the abnormally tall R waves in V1-V2 are a clue as they are reciprocal changes
What is a systolic crescendo-decrescendo murmur that becomes louder with valsalva?
HOCM; the murmur will become louder with things that decrease the preload; AS does not really change with valsalva
Best mgmt of afib with RVR in COPD?
CCB > BB due to bronchospasm
How do you decide on anticoagulation in a pt with Afib due to hyperthyroidism?
Still CHADSVASC i.e. if 0 then no need to AC there is no increased risk just bc it is due to hyperthyroidism
What is the dose of clopidogrel for NSTEMI?
300-600 mg load then 75 mg daily but careful as you don?t know if the pt will need a CABG
What is a normal ABI? Borderline low? Low? Uninterpretable?
Normal is 1-1.4; Borderline low is 0.91-1, Low is <0.9; uninterpretable is >1.4
How long should a stent, whether BMS or DES be kept on DAPT after being placed for ACS?
1 year; if a BMS was placed for reason other than ACS then can be on DAPT for 1 month or if need surgery
What is the most appropriate next step to further evaluate a pt with pleuritic CP, a pericardial rub and a nonspecific EKG?
TTE as it can show a pericardial effusion to help with the Dx of pericarditis; the classic EKG has diffuse ST elevation and PR depression
What did the FREEDOM trial show?
That DM pts with reduced systolic fxn with multivessel dz do better with CABG than with PCI
What is the best anticoagulant to give to a pt with NSTEMI who is to be treated in a non-invasive, ischemia directed way? What about early invasive?
LMWH (lovenox); if planning intervention i.e. early invasive approach (within 24 hours) then UFH is better bc can shutoff
What is the murmur of diastolic decrescendo with diastolic rumble?
Austin Flint murmur of AR; diastolic decrescendo is the AR then the rumble is the functional MS due to the regurgitant jet
How does subclavian steal present?
Often after a CABG with LIMA-LAD in a pt with arm pain, angina, and vertebrobasilar insuff
What should be added to the usual tx of HFrEF in black patients?
Hydralazine + Nitrates (Isosorbide dinitrate) if NYHA III-IV (added to ACE-I, BB, and aldosterone antagonist)
What should you do for a pt with a STEMI at a PCI incapable hospital 3 hours from a PCI capable center who had an ischemic stroke 2 months ago?
ASA and thienopyridine, fibrinolytics are contraindicated
What is the mgmt of cyanotic heart dz with erythrocytosis?
No intervention unless the hematocrit is >65% or there is evidence of hyperviscosity sx
What is the Tx of most pt with structural heart dz who have PVCs or NSVT (<30 sec)?
Their presence does NOT predict sudden cardiac death (the EF is better for predicting that) and their suppression is not useful; however, if symptomatic can be on BB and if >10% of all beats can do catheter ablation
What is theoretically a good tx for a pt with HTN emergency with acute heart failure?
IV nitroglycerin
What is the appropriate surveillance of aortic root dilation in Marfan syndrome?
One time 6 months after Dx then annually assuming that the size remains stable
What is the Tx of Dressler Syndrome?
High dose ASA and Colchicine (avoid NSAIDS)–of note NSAIDs ok in pericarditis NOT assoc with MI
What is the most appropriate mgmt of a pt with suspected PAD who has an ABI of >1.4
Since that is an uninterpretable ABI the measurement of GREAT TOE SYSTOLI PRESSURE can establish the Dx
What is the most likely cause of a new mid-late systolic murmur that develops after an acute inferior MI in a clinically stable pt without sx of CHF?
Papillary muscle displacement (the old papillary muscle dysfxn); diff from papillary muscle rupture which would have acute heart failure or cardiogenic shock
What is the best diagnostic test for a patient with infrequent palpitations a couple of times per month?
Cardiac Event Recorder (30 day recorder)
Best dx test for a woman from Guatemala with conduction abnormalities, CHF and GERD
T. cruzi IgG levels
What is the most likely Dx for unexplained syncope, RV dysfxn, and TWI in V1-V3 with FMHx sudden cardiac death
ARVC (plakoglobin)–fibrofatty infiltration of RV myocardium
What are the best initial drugs to start a pt on with HFrEF once they are euvolemic/compensated?
ACE/ARB first then a beta blocker; ACE are typically started first due to beneficial hemodynamic effects; BBs then started and titrated up q1-2 weeks or so until target dose
What is the first line mgmt of a pt with intermediate risk of CAD?
Exercise stress test (w/ exercise EKG stress preferred unless LBBB, pre-excitation, or baseline ST-T wave changes) second line pharmacologic
What are clinical markers of reperfusion in pt who have received lytics for STEMI?
Improvement in CP, improvement >70% in ST elevation, reperfusion arrhythmias i.e. accelerated idioventricular rhythm
What is the treatment of high degree AV block in Lyme dz?
IV CTX and possibly temporary transvenous pacing if needed for stability but rarely need a PPM
What is the most appropriate mgmt for a pt with suspected constrictive pericarditis who has an uninterpretable TTE?
Right Heart Catheterization (look for square root sign)
How do you risk stratify for anticoagulation after catheter ablation for afib?
Still based on CHADSVASC and NOT based on their rhythm status
What medication should be added to a pt with STEMI who has undergone thrombolysis?
Clopidogrel 300 mg PO (CLARITY-TIMI-28 study); other thienopyridines have not been studied in the post-fibrinolytic setting; otherwise for STEMI, ticagrelor and prasugrel are better
What is Wellen Syndrome?
A proximal LAD occlusion manifested by CP with deep symmetric TWIs in V2-V3 with flat ST segment
What is the best test for a pt presenting with Amaurosis fugax?
Carotid US to look for extracranial dz, could consider CTA or MRA if negative for intracranial stenosis
What is a specific finding on TTE for cardiac tamponade? What may be seen on EKG?
Early RV collapse; R heart cath showed equilization of pressures and EKG shows electrical alternans
How frequently should patients with asymptomatic bicuspid AoV undergo surveillance TTE?
Yearly if the aortic root or ascending aorta is >4.5 cm
When is a baby aspirin indicated in DM pts?
If clinical ASCVD or if ASCVD risk >10%
What can improve LV EF in pt with HFrEF due to iron overload?
Iron chelation therapy; if primary hemochromatosis then maintenance phlebotomy as well but not if secondary (i.e. due sickle cell etc)
Why might you place a Holter monitor on a pt with newly diagnosed, asymptomatic atrial fibrillation?
Because if the average HR is >110 bpm would consider rate-controlling the pt
A patient who has had a catheter ablation of AF with unexplained dyspnea raises concern for what?
Pulmonary Vein Stenosis; several diagnostic modalities: CT angio, MRI, etc
What is the best mgmt for a pt with recurrent malignant pericardial effusions?
Subxiphoid Pericardotomy (Pericardial Window)
What are 3 indications for AICD in HOCM?
If pt has hx of cardiac arrest, spontaneous sustained VT (>30 sec) or syncope, or >2 family members with sudden cardiac death
How can you differentiate the murmur of HOCM from that of AS?
HOCM gets louder with things that decrease the preload i.e. valsalva and softer with squatting as it increases preload; AS does not really change and if anything would get softer with a decrese in preload
What is considered frequent PVCs? What is the complication? Tx?
Frequent PVCs are ones that are >10% of all beats or >10,000 beats per day; if symptomatic tx is BB; if they are causing a cardiomyopathy then need to perform ablation
What can tell you the likelihood that a person has a DVT?
Well’s criteria
What is the difference between a massive and submassive PE?
A massive PE is one with HoTN; a submassive PE is normotensive but has evidence of R heart strain on TTE, EKG (S1Q3T3), or elevated trop
What are the creatinine cutoffs for starting aldosterone antagonists?
sCr >2 in women, 2.5 in men
Who gets tendinous xanthomas?
Pathognomonic for Familial Hypercholesterolemia (Palmar xanthomas are in abetalipoproteinemia)