MKSAP STOCK3 Flashcards
What is the additional treatment indicated in all patients with small cell lung cancer who experience a remission following chemotherapy and radiation therapy to the chest?
Prophylactic Cranial Irradiation
What is the treatment indicated for patients with recurrent Hodgkin lymphoma who achieve a complete response to salvage chemotherapy?
Autologous Hematopoetic stem cell transplant
What is the recommended imaging surveillance following treatment of early-stage breast cancer in asymptomatic patients?
Annual mammography
What is the therapeutic option for patients with bone-limited, symptomatic metastatic prostate cancer?
Radiopharmaceutical agent Radium 223
What is the recommended additional postsurgical therapy for patients with early-stage, triple-negative breast cancer >0.6 cm?
Chemotherapy (often anthracycline based)
What is the recommended breast cancer screening regimen for women who received chest wall radiation between ages 10 and 30 years?
Annual mammogram and breast MRI
What adjuvant treatment following surgical resection is shown to improve survival in patients with stage II or stage III non-small cell lung cancer?
Cisplatin based chemotherapy
What is the optimal method of tissue sampling to diagnose lymphoma?
Excisional lymph node biopsy
What is the recommended strategy for an older man with significantly limited life expectancy (<10 years) with newly diagnosed low risk prostate CA?
Clinical Observation
What is the standard treatment regimen for patients with stage I, II, or III anal squamous cell carcinoma?
Chemoradiation (w/ mitomycin C)
What is the mgmt for incidentally discovered, low grade, hormonally nonfunctional, metastatic carcinoid tumor?
Expectant observation with periodic repeat imaging
What is the management of patients with imaging compatible with resectable pancreatic cancer
Definitive resection WITHOUT previous tissue confirmation
Appropriate management strategy in patients with a history of treated breast cancer who develop findings suspicious for metastatic disease
Biopsy of suspected metastatic site to confirm diagnosis and to assess hormone receptor status and HER2 status
Management of a patient with metastatic cancer and poor performance status
Palliative care
What is the most likely diagnosis in a patient with microscopic hematuria, midback pain, erythrocytosis, and elevated erythropoetin
Renal Cell Carcinoma
Adjuvant therapy shown to improve outcomes in patients with high risk, localized gastrointestinal stromal tumors
Imatinib
Definition of neutropenic fever in patients undergoing cancer treatment
Fever w/ neutrophil count <1000 (often, actually <500)
What is the recommended management of men with persistently elevated prostate-specific antigen level immediately following radical prostatectomy
Androgen Deprivation Therapy
What is the recommended initial treatment of patients with early-stage head and neck cancer?
Either surgery or primary radiotherapy
Treatment for metastatic recurrence of pancreatic cancer in patients with good performance status
Multiagent Systemic Chemotherapy
Most common metabolic complication associated with Burkitt lymphoma
Tumor lysis syndrome
What is the recommended treatment for high-grade, poorly differentiated neuroendocrine tumors of unknown primary site
Platinum-based systemic chemotherapy
Recommended adjuvant endocrine therapy following breast cancer treatment for a premenopausal woman?
Tamoxifen for AT LEAST 5 years but PREFERABLY 10 years
What is the treatment of choice for hyperuricemia in a gout patient with an adverse reaction to allopurinol?
Febuxostat
What is a nonerosive arthritis associated with systemic lupus erythematosus?
Jaccoud Arthropathy
The combination of these two laboratory tests has the greatest specificity for diagnosing rheumatoid arthritis
Anti-CCP; Rheumatoid factor
What is the type of dermatomyositis with cutaneous involvement in the absence of clinical, laboratory, electromyogram, or biopsy evidence of muscle inflammation?
Amopathic Dermatomyositis
Treatment for inadequately controlled osteoarthritis in one symptomatic joint
Intra-articular glucocorticoids
What is the treatment for acute monoarticular gout when oral therapies have potential adverse event
Intra-articular glucocorticoids
What is the treatment of severe Henoch Schonlein Purpura with multi-organ system involvement
Glucocorticoids
What is the indication for use of multiple biologic agents to treat rheumatologic disease?
None if you’re going to use them you just use one
What are four symptoms that must be present for >3 months in order to diagnose fibromyalgia
Chronic widespread pain, fatigue, waking up unrefreshed, and cognitive symptoms
Neonatal cardiac complication of maternal systemic lupus erythematosus with positive anti-Ro/SSA antibodies
Congenital Heart Block
Underlying cause of secondary osteoarthritis of metacarpophalangeal and wrist joints
Hemochromatosis
What is the most sensitive imaging test for diagnosing suspected spondyloarthritis
MRI of spine and sacroiliac joints
What is the test of choice for pulmonary hypertension in patients with underlying rheumatologic disease?
Echocardiography
Pulmonary disease associated with polymyositis and positive anti-Jo-1 antibodies
Interstitial Lung Disease
What biologic agent is associated with the risk of an abnormal lipid panel
Tofacitinib (Xeljanz)
What is the target serum urate level for secondary prevention of gout?
<6.0
What is the initial treatment of patients with suspected giant cell arteritis?
High dose prednisone (60 mg daily)
What is the preferred tuberculosis screening for patients starting a biologic agent who are already on nonbiologic immunosuppressive therapy?
Interferon gamma release assay
What disease is characterized by inflammatory back pain and stiffness in the lower spine that worsens after immobility and improves with use
Ankylosing Spondylitis
What connective tissue disease has a markedly increased risk of developing lymphoma?
Sjogren syndrome
What serologic test is useful in patients with an intermediate probability of having spondyloarthritis?
HLA-B27
What disease is diagnosed by fever, polyserositis, and arthritis that improves with a trial of colchicine
Familial Mediterranean Fever
What antidepressant medication has shown to reduce pain and improve functioning in patients with knee osteoarthritis
Duloxetine
Treatment of choice for interstitial lung disease associated with diffuse systemic sclerosis?
Cyclophosphamide
What is the test of choice to diagnose the cause of acute monoarticular arthritis?
Synovial Fluid Analysis
What are six clinical characteristics of psoriatic arthritis
Enthesitis, Dactylitis, Tenosynovitis, Arthritis of the distal interphalangeal joints, asymmetric oligoarthritis, and spondylitis
What disease is characterized by eosinophilia, MIGRATORY pulmonary infiltrates, purpuric skin rash, and mononeuritis multiplex
Eosinophilic Granulomatosis with Polyangiitis
