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ABIM > MKSAP STOCK3 > Flashcards

MKSAP STOCK3 Flashcards

1
Q

What is the additional treatment indicated in all patients with small cell lung cancer who experience a remission following chemotherapy and radiation therapy to the chest?

A

Prophylactic Cranial Irradiation

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2
Q

What is the treatment indicated for patients with recurrent Hodgkin lymphoma who achieve a complete response to salvage chemotherapy?

A

Autologous Hematopoetic stem cell transplant

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3
Q

What is the recommended imaging surveillance following treatment of early-stage breast cancer in asymptomatic patients?

A

Annual mammography

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4
Q

What is the therapeutic option for patients with bone-limited, symptomatic metastatic prostate cancer?

A

Radiopharmaceutical agent Radium 223

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5
Q

What is the recommended additional postsurgical therapy for patients with early-stage, triple-negative breast cancer >0.6 cm?

A

Chemotherapy (often anthracycline based)

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6
Q

What is the recommended breast cancer screening regimen for women who received chest wall radiation between ages 10 and 30 years?

A

Annual mammogram and breast MRI

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7
Q

What adjuvant treatment following surgical resection is shown to improve survival in patients with stage II or stage III non-small cell lung cancer?

A

Cisplatin based chemotherapy

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8
Q

What is the optimal method of tissue sampling to diagnose lymphoma?

A

Excisional lymph node biopsy

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9
Q

What is the recommended strategy for an older man with significantly limited life expectancy (<10 years) with newly diagnosed low risk prostate CA?

A

Clinical Observation

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10
Q

What is the standard treatment regimen for patients with stage I, II, or III anal squamous cell carcinoma?

A

Chemoradiation (w/ mitomycin C)

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11
Q

What is the mgmt for incidentally discovered, low grade, hormonally nonfunctional, metastatic carcinoid tumor?

A

Expectant observation with periodic repeat imaging

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12
Q

What is the management of patients with imaging compatible with resectable pancreatic cancer

A

Definitive resection WITHOUT previous tissue confirmation

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13
Q

Appropriate management strategy in patients with a history of treated breast cancer who develop findings suspicious for metastatic disease

A

Biopsy of suspected metastatic site to confirm diagnosis and to assess hormone receptor status and HER2 status

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14
Q

Management of a patient with metastatic cancer and poor performance status

A

Palliative care

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15
Q

What is the most likely diagnosis in a patient with microscopic hematuria, midback pain, erythrocytosis, and elevated erythropoetin

A

Renal Cell Carcinoma

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16
Q

Adjuvant therapy shown to improve outcomes in patients with high risk, localized gastrointestinal stromal tumors

A

Imatinib

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17
Q

Definition of neutropenic fever in patients undergoing cancer treatment

A

Fever w/ neutrophil count <1000 (often, actually <500)

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18
Q

What is the recommended management of men with persistently elevated prostate-specific antigen level immediately following radical prostatectomy

A

Androgen Deprivation Therapy

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19
Q

What is the recommended initial treatment of patients with early-stage head and neck cancer?

A

Either surgery or primary radiotherapy

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20
Q

Treatment for metastatic recurrence of pancreatic cancer in patients with good performance status

A

Multiagent Systemic Chemotherapy

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21
Q

Most common metabolic complication associated with Burkitt lymphoma

A

Tumor lysis syndrome

22
Q

What is the recommended treatment for high-grade, poorly differentiated neuroendocrine tumors of unknown primary site

A

Platinum-based systemic chemotherapy

23
Q

Recommended adjuvant endocrine therapy following breast cancer treatment for a premenopausal woman?

A

Tamoxifen for AT LEAST 5 years but PREFERABLY 10 years

24
Q

What is the treatment of choice for hyperuricemia in a gout patient with an adverse reaction to allopurinol?

A

Febuxostat

25
Q

What is a nonerosive arthritis associated with systemic lupus erythematosus?

A

Jaccoud Arthropathy

26
Q

The combination of these two laboratory tests has the greatest specificity for diagnosing rheumatoid arthritis

A

Anti-CCP; Rheumatoid factor

27
Q

What is the type of dermatomyositis with cutaneous involvement in the absence of clinical, laboratory, electromyogram, or biopsy evidence of muscle inflammation?

A

Amopathic Dermatomyositis

28
Q

Treatment for inadequately controlled osteoarthritis in one symptomatic joint

A

Intra-articular glucocorticoids

29
Q

What is the treatment for acute monoarticular gout when oral therapies have potential adverse event

A

Intra-articular glucocorticoids

30
Q

What is the treatment of severe Henoch Schonlein Purpura with multi-organ system involvement

A

Glucocorticoids

31
Q

What is the indication for use of multiple biologic agents to treat rheumatologic disease?

A

None if you’re going to use them you just use one

32
Q

What are four symptoms that must be present for >3 months in order to diagnose fibromyalgia

A

Chronic widespread pain, fatigue, waking up unrefreshed, and cognitive symptoms

33
Q

Neonatal cardiac complication of maternal systemic lupus erythematosus with positive anti-Ro/SSA antibodies

A

Congenital Heart Block

34
Q

Underlying cause of secondary osteoarthritis of metacarpophalangeal and wrist joints

A

Hemochromatosis

35
Q

What is the most sensitive imaging test for diagnosing suspected spondyloarthritis

A

MRI of spine and sacroiliac joints

36
Q

What is the test of choice for pulmonary hypertension in patients with underlying rheumatologic disease?

A

Echocardiography

37
Q

Pulmonary disease associated with polymyositis and positive anti-Jo-1 antibodies

A

Interstitial Lung Disease

38
Q

What biologic agent is associated with the risk of an abnormal lipid panel

A

Tofacitinib (Xeljanz)

39
Q

What is the target serum urate level for secondary prevention of gout?

A

<6.0

40
Q

What is the initial treatment of patients with suspected giant cell arteritis?

A

High dose prednisone (60 mg daily)

41
Q

What is the preferred tuberculosis screening for patients starting a biologic agent who are already on nonbiologic immunosuppressive therapy?

A

Interferon gamma release assay

42
Q

What disease is characterized by inflammatory back pain and stiffness in the lower spine that worsens after immobility and improves with use

A

Ankylosing Spondylitis

43
Q

What connective tissue disease has a markedly increased risk of developing lymphoma?

A

Sjogren syndrome

44
Q

What serologic test is useful in patients with an intermediate probability of having spondyloarthritis?

A

HLA-B27

45
Q

What disease is diagnosed by fever, polyserositis, and arthritis that improves with a trial of colchicine

A

Familial Mediterranean Fever

46
Q

What antidepressant medication has shown to reduce pain and improve functioning in patients with knee osteoarthritis

A

Duloxetine

47
Q

Treatment of choice for interstitial lung disease associated with diffuse systemic sclerosis?

A

Cyclophosphamide

48
Q

What is the test of choice to diagnose the cause of acute monoarticular arthritis?

A

Synovial Fluid Analysis

49
Q

What are six clinical characteristics of psoriatic arthritis

A

Enthesitis, Dactylitis, Tenosynovitis, Arthritis of the distal interphalangeal joints, asymmetric oligoarthritis, and spondylitis

50
Q

What disease is characterized by eosinophilia, MIGRATORY pulmonary infiltrates, purpuric skin rash, and mononeuritis multiplex

A

Eosinophilic Granulomatosis with Polyangiitis

ABIM (9 decks)

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