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MKSAP > MKSAP quiz 1 > Flashcards

MKSAP quiz 1 Flashcards

1
Q

Rx of ILD in systemic sclerosis

A

Mycophenolate mofetil>cyclophosphamide

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2
Q

Rx of laceration over a finger joint

A

sutures

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3
Q

Risk with using GC in scleroderma

A

Renal crisis

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4
Q

Rx of Raynaud’s

A

CCB, Sildenafil; losartan; prazosin, Topical nitrates; low-dose aspirin, Digital sympathectomy

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5
Q

severe HTn, AKI, normal UA/mild pruria/no cells in pt with scleroderma

A

Scleroderma renal crisis

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6
Q

Rx of scleroderma renal crisis

A

ACEI - preferably captopril, might need temporary dialysis

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7
Q

Rx of gi dysmotility (pro-motility agents)

A

Metoclopramide (avoid long-term use); domperidone

Erythromycin; cisapride

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8
Q

Px Scleroderma renal crisis

A

CCB

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9
Q

Ab in scleroderma

A

Scl 70/topoisomerase 1, centromere, RNA polym III

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10
Q

Scl 70 Ab in SS asso. with

A

lung fibrosis

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11
Q

Ab giving protection from lung and kidney ds in SS

A

centromere

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12
Q

Centromere ab in SS asso. with

A

pulm HTn, esoph ds

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13
Q

RNA polymerase III in SS asso. with

A

renal, skin, malignancy

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14
Q

Ab in limited SS

A

centromere

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15
Q

MC pathogen in COPD exacerbation

A

H. influenzae

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16
Q

SE of sodium polystyrene sulfate used for HK

A

gi tox - ulcerations, perforation

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17
Q

reversal of dabigatran

A

idarucizumab, a monoclonal antibody fragment that binds free and thrombin-bound dabigatran/activated PCC

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18
Q

NOAC not needing renal dosing

A

Betrixaban

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19
Q

reversal of Xa agents

A

andexanet(only if life threatening bleeding)/4 factor PCC

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20
Q

NOAC approved for pts undergoing dialysis

A

eliquis/apixaban

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21
Q

tenofovir alafenamide is preferred over tenofovir disoproxil fumarate because

A

lower nephrotoxicity and risk of osteopenia

22
Q

ART alternative in ppl with chilbearing potential/not using contraception

A

Dolutegravir

23
Q

cutaneous sclerosis that involves only the skin in the absence of other systemic manifestations of systemic sclerosis

A

morphea

24
Q

Diffuse cutaneous SS characterized by

A

skin thickening that involves areas proximal to the elbows and/or knees.

25
Q

Limited cutaneous SS characterized by

A

skin disease that does not progress proximal to the elbows or knees but may include the face and neck.

26
Q

Linear scleroderma characterized by

A

skin thickening that follows a dermatomal distribution on one side of the body.

27
Q

linear morphea affecting face/scalp involving underlying subcutaneous tissues, muscle and bone.

A

En coup de sabre

28
Q

ABx of choice to px SSI

A

Cefazoline

29
Q

Rx opioid addiction

A

buprenorphine - reduces cravings

30
Q

MOA of buprenorphine

A

partial opioid agonist - binds strongly but minimum activation

31
Q

prevent relapse in patients with opioid and alcohol use disorders

A

Naltrexone

32
Q

Drug which decreases adenoma in FAP

A

Sulindac (NSAID), aspirin

33
Q

Attenuated FAP

A

<100 but >10 polyps, 80% risk of CRC

34
Q

Turcot syndrome

A

FAP with cns tumors

35
Q

Screening for FAP

A

If risk for classic: sigmoidoscopy/colonoscopy annually starting at 10-12 y.o
If risk for attenuated: Every 1-2 y starting at 25 y

36
Q

Drugs preferred for HIV rx

A

Nrti: Tenofovir, emtiracitabine

Integrase inhib: dolutegravir

37
Q

Rx of prolactinoma

A

DA ag - cabergoline, bromocriptine

38
Q

Anti-HTn meds associated with hyperprolactinemia

A

Verapamil, methyldopa

39
Q

Ab in systemic sclerosis which increases risk of ILD

A

anti–Scl-70 (DNA topoisomerase-1)

40
Q

Rx of raynaud’s

A

CCB, Sildenafil; losartan; prazosin, Topical nitrates; low-dose aspirin, Digital sympathectomy

41
Q

mild COPD exacerbation

A

when a change in the clinical condition is noted but no change in medication is necessary

42
Q

Severe COPD exacerbation

A

if ED eval/hospitalization needed or 2 offollowing symptoms: increased dyspnea, increased sputum volume, or increased sputum purulence

43
Q

Pseudomonas infection RF in COPD exacerbation

A

Frequent administration of antibiotics (four or more courses over the past year); recent hospitalization (two or more days duration in the past 90 days); isolation of Pseudomonas during a previous hospitalization; severe underlying COPD (FEV1 <50 percent predicted).

44
Q

Sodium polystyrene sulfate /Kayexalate SE

A

GI bleed/ulcerations/perforation

45
Q

STICH Trial

A

Surg rx for ischemic HF<35%: all cause mortality dec with cabg act medical

46
Q

Naloxone given to

A

Subs use ds, opioids+bdz, >50morphine meq/d, older, mental ds, osa

47
Q

Ca seen in FAP

A

CRC>duod/periampullary>gastric, papillary/follicular thyroid ca, cns tumors (turcot), desmoid

48
Q

Classic FAP

A

> 100 polyps, 100%colon ca

49
Q

Metoclopramide should not be used for more than 12 weeks because (black box)

A

Tardive dyskinesia (maybe irrev)

50
Q

Lab monitoring in hypoparathyroidism

A

Ca, mg, P, urine ca, creat

51
Q

Most effective intervention to prevent pressure injuries

A

Advanced static mattress

MKSAP (1 decks)

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