Mixing (Blending) Flashcards

1
Q

a process in which two or more ingredients in separate or roughly mixed conditions are treated so that each particle of any one ingredient is as nearly as possible adjacent to a particle of each of the other ingredients

A

Mixing (Blending)

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2
Q

This is usually accomplished utilizing paddles, revolving blades, or other devices within the mixer, arranged to move adjacent volumes of the fluid in different directions, thereby shuffling the system in three dimensions

A

Bulk transport

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3
Q

• velocity differences within the body of fluid produce randomization of the fluid molecules. For this reason, turbulence is a highly effective mechanism of mixing.

A

Turbulent mixing

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4
Q

highly viscous fluids are being processed.

A

Laminar mixing

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5
Q

Just read

A

When two different liquids are mixed through laminar flow, the generated shear stretches the interface between them

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6
Q

The primary mechanism responsible for mixing at the molecular level is ____ resulting from the thermal motion of the molecules.

A

diffusion

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7
Q

When it occurs in conjunction with laminar flow __ tends to reduce the sharp discontinuities at the interface between the fluid layers and, if allowed to proceed for sufficient time, results in complete mixing

A

Molecular diffusion

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8
Q

A system for liquid mixing commonly consists of two primary components:

A
  1. a tank or other container suitable for holding the material being mixed
  2. means supplying energy to the system to facilitate reasonably rapid mixing
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9
Q

The distinction between impeller types is often made based on

A
  1. type of flow pattern they produce
  2. the blades’ shape and pitch
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10
Q

In impellers the flow pattern may be analyzed in terms of three components:

A

radial, axial or longitudinal, tangential

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11
Q

perpendicular to the impeller shaft

A

radial

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12
Q

parallel to the impeller shaft

A

axial or longitudinal

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13
Q

tangential to the circle of rotation around the impeller shaft

A

tangential

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14
Q
  • the segment of a multithreaded screw
  • either right- or left-handed depending on the direction of slant of their blades
A

Propellers

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15
Q

• The three-blade design is most commonly used with fluids
• most efficient when they run at high speeds in liquids of relatively low viscosity

A

Propellers

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16
Q

the primary effect of a propeller is due to a __.

A

axial flow

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17
Q

With these types of impellers, a radial flow is induced by the centrifugal action of the revolving blades

A

Turbines

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18
Q

When radial-tangential flow is desired, turbines with blades set at a 90-degree angle to their shaft are employed

A

Turbines

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19
Q

can be operated satisfactorily in fluids 1000 times more viscous than fluids in which a propeller of comparable size can be used

A

Turbines

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20
Q

generally operated at low speeds of 50 rpm or less

A

Paddles

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21
Q

Their blades have a large surface area as compared to the tank in which they are employed, a feature that permits them to pass close to the tank walls and effectively mix viscous liquids and semisolids

A

Paddles

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22
Q

• involve sub-surface jets of air, or less commonly of some other gas, for adequate mixing of certain liquids
• The jets are usually arranged so that the buoyancy of the bubbles lifts liquids from the bottom to the top of the mixing vessel
• the intense turbulence generated by the jet produces intimate mixing

A

Air jets

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23
Q

They utilize liquids pumped at high pressure into a tank for mixing

A

Fluid jets

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24
Q

the fluids are pumped through nozzles arranged to permit a good circulation of material throughout the tank

A

Fluid jets

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25
produces an uninterrupted supply of freshly mixed material and is often desirable when huge volumes of materials are to be handled.
Continuous mixing
26
CONTINUOUS OR IN-LINE MIXERS can be accomplished in two ways
1. tube or pipe 2. mixing chamber
27
CONTINUOUS OR IN-LINE MIXERS way in which the material flows and in which there is very little backflow or recirculation
tube or pipe
28
CONTINUOUS OR IN-LINE MIXERS way in which a considerable amount of holdup and recirculation occurs
mixing chamber
29
Semi-solid mixing mechanism
1. Powder state 2. Pellet state 3. Plastic state 4. Sticky state 5. Liquid state
30
the initial powder (starting material)
powder state
31
when the amount of liquid is added to the powder→ coarse granules
pellet state
32
granular appearance is lost; becomes homogenous
Plastic state
33
paste-like appearance due to continual incorporation of liquid
Sticky state
34
Further addition of liquid decreases consistency until fluid State is reached
Liquid state
35
Has counter-rotating blades or heavy arms that work the plastic mass.
Sigma-Blade mixer
36
Sigma-Blade mixer- The blades rotate tangentially with a speed ratio of about ____.
2:1
37
The mixing element rotates around the circumference of the mixer's container while simultaneously rotating about its axis
Planetary mixer
38
Planetary mixer just read
The double rotation of the mixing element and its offset position reduces the dead zones and avoids vortex formation
39
Provide forces that incorporate kneading, shearing, smearing, and blending of materials for total uniform consistency
Mulling Mixers
40
This process produces enough pressure to move, intermingle and push particles into place without crushing, grinding, or distorting the ingredients
Mulling Mixers
41
The result of this mixer is a truly uniform consistency in both physical and chemical structure
Mulling mixers
42
2 mils
Roller mills Colloid mills
43
Consist of one or more rollers and are commonly used.
Roller mills
44
the three-roller mills types that are preferred are...
Apron roll Center roll Feed roll
45
consists of a high-speed rotor (3,000 to 20,000 rpm) and a stator with conical milling surfaces between which an adjustable clearance ranging from 0.002 to 0.03 inches is present
Colloid mill
46
Solid mixing (Mixing mechanisms 3)
1. Convective Mixing 2. Shear Mixing 3. Diffusive mixing
47
can occur by an inversion of the powder bed, by means of blades, paddles, a revolving screw, or by any other method of moving a relatively large mass of material from one part of the powder bed to another
convective mixing
48
the fastest and most efficient mixing mechanism
convective mixing
49
When shear occurs between regions of different composition and parallel to their interface, it reduces the scale of segregation by thinning the dissimilar layers
Shear Mixing
50
Large or irregular grains of powder tend to be expelled from regions of high shear through a mechanism known
shear-induced migration
51
is the rate-limiting mechanism for mixing
Diffusion
52
consists of a container of the one of several geometric forms, which is mounted so that it can be rotated about an axis to cause movement of the material in all planes, which is necessary for rapid overall mixing.
Tumblers/Blenders-A tumbling mixer
53
employ a stationary container to hold the material and bring about mixing by means of moving screws, paddles, or blades
Agitators mixers
54
employ a stationary container to hold the material and bring about mixing by means of moving screws, paddles, or blades
Agitators mixers
55
It consists of a horizontal cylindrical tank usually opening at the top and fitted with helical blades or ribbons
Ribbon Mixer/Blender
56
The blades are mounted on the horizontal axle by struts, and are rotated to circulate the material to be mixed.
Ribbon Mixer/Blender
57
The helical blades are wound (in most cases) in the opposite directions to provide for the movement of material in both directions along the axis of the tank
Ribbon Mixer/Blender
58
also used for solid-solid blending although mostly in a step prior to the introduction of liquids
Planetary Mixers
59
A screw assembly is mounted in a conical chamber, with the screw moving in a planetary motion, and also lifting the powder to be blended from the bottom to the top
Nauta mixers
60
It is a modification of the vertical impeller.
Fluidized Air Mixer
61
The impeller is replaced by a rapidly moving stream of air fed into the bottom of the shell. The body of powder is fluidized, and mixing is accomplished by circulation and over tumbling in the bed
Fluidized Air Mixer
62
can accomplish both dry mixing and wet granulation efficiently, and in lesser time
Processors or Rapid Mixer-Granulator
63
was one of the first high-shear powder blenders capable of rapidly blending pharmaceutical powders and wet massing within the same equipment
Lödige Mixer
64
It is another type of high-speed powder mixer and processor. The mixer utilizes a bowl mounted in the vertical position, a highspeed mixer blade that revolves around the bottom of the bowl and a high-speed chopper blade, which functions as a lump and agglomerate breaker
Diosna Mixer-Granulator
65
modification of the industrial planetary mixers
Gral Mixer-Granulator
66
Provides composition uniformity especially in manufacturing tablets and capsules
Continuous Mixers
67
It consists of a series of fixed, flow-twisting or flow-splitting elements designed for blending of free-flowing solids
Blendex
68
provides efficient mixing for a variety of solids without heat generation or particle size reduction
Blendex
69
• material is mixed under tumbling motion • provides intense mixing of ingredients
Barrel Type Continuous Mixer
70
consists of several “V”-shaped blenders connected in series
Zig-zag Continuous Blender
71
When the blender is inverted, the material splits into two portions, one-half of the material moves backwards, while the other moves forward
Zig-zag Continuous Blender