Mixed

Question 1

Eczema + recurrent infection + thrombocytopenia

Answer 1

Wiskott-Aldrich syndrome

Question 2

Hemosiderinuria+ thrombosis

Answer 2

Paroxysmal nocturnal hemoglobinuria

Question 3

After an spontaneous normal delivery a new mom bleed profusely from the vagina and later from her gums. Labs= high BT, PTT, PT and D-dimer; low platelets and fibrinogen

Answer 3

DIC (Disseminated intravascular coagulation)

Question 4

Enzyme deficient in:
1-Fructose intolerance

2-Essential fructosuria

3-Classic galactosemia

Answer 4

1- Aldolase B

2-Fruntokinase

3-Galactise-1-phosphate uridyltransferase

Question 5

Pathology of thyroid cell with optically clear nuclei

Answer 5

Papillary carcinoma of the thyroid

Question 6

Anemia with hypersegmented neutrophils

Answer 6

Macrocytic megaloblastic anemia

• B 12 deficiency
• Folate deficiency

Question 7

Branching rods on oral infection

Answer 7

Actinomyces israelii

Question 8

Most common lymphoma in USA

Answer 8

Diffuse large B lymphoma

Question 9

Reed-sternberg cells

Answer 9

Hodgkin lymphoma

Question 10

Lymphoma associated to EBV

Answer 10

Burkitt lymphoma

Hodgkin lymphoma

Question 11

Burkitt lymphoma translocation

Answer 11

t(8;14)

Question 12

Lymphoma equivalent of CLL

Answer 12

Small lymphocytic lymphoma

Question 13

‘Starry-sky pattern” due to phagocytosis of apoptotic tumor cell

Answer 13

Burkitt lymphoma

Question 14

Associated with Sjögren syndrome, Hashimoto thyroiditis, and H. pylori

Answer 14

Marginal zone lymphoma

t(11;18)

Question 15

Cancer most commonly associated with a noninfectious fever

Answer 15

Hodgkin lymphoma

Question 16

Large B cell with bilobed nuclei and prominent “owls eye inclusions”

Answer 16

Reed-Sternberg cells seen in Hodgkin lymphoma

Question 17

Defect in platelet plug formation. Result in large platelets

Answer 17

Bernard-Soulier syndrome

Question 18

Bone marrow filled with adipocytes and absence of splenomegaly

Answer 18

Aplastic anemia

Question 19

CREST scleroderma

Answer 19

Calcinosis
Raynauld phenomenon
Esophageal dysmotility
Sclerodactyly
Telangiectasias

Question 20

Penicillin mode of action

Answer 20

• Bind penicillin-binding proteins
• Blocks traspeptidase cross-linking of cell wall
• Activates autolytic enzymes
• bactericidal

Question 21

Dermatitis, dementia, diarrhea

Answer 21

Niacin(B3) deficiency (Pellagra)

Question 22

Red urine in the morning, fragile RBCs

Answer 22

Paroxysmal Nocturnal Hemoglobinuria

Question 23

Cardio

Maternal lithium use

Answer 23

Ebstein anomaly

Question 24

Cardio

Maternal alcohol use

Answer 24

Tetralogy of fallot
VSD
ASD
PDA

Question 25

Cardio Pregestational diabetes

Answer 25

Transposition of great vessels

Question 26

Cardio Congenital rubella

Answer 26

PDA | Pulmonary artery stenosis

Question 27

DiGeorge syndrome (22q11 syndrome)

Answer 27

Tetralogy of fallot | Truncus arteriosus

Question 28

Cardio Turner syndrome

Answer 28

Coarctation of aorta | Bicuspid aortic valve

Question 29

Cardio Trisomy 21

Answer 29

Endocardial cushions defect(ASD,VSD)

Question 30

Continuous machinery-like heart murmur

Answer 30

PDA

Question 31

"Boot shaped heart"

Answer 31

Tetralogy of fallot | RVH in adult

Question 32

Rib notching

Answer 32

Coarctation of aorta

Question 33

Most common congenital cardiac anomaly

Answer 33

VSD

Question 34

Most common congenital cause of early cyanosis

Answer 34

Tetralogy of fallot