Mixed Flashcards
Eczema + recurrent infection + thrombocytopenia
Wiskott-Aldrich syndrome
Hemosiderinuria+ thrombosis
Paroxysmal nocturnal hemoglobinuria
After an spontaneous normal delivery a new mom bleed profusely from the vagina and later from her gums. Labs= high BT, PTT, PT and D-dimer; low platelets and fibrinogen
DIC (Disseminated intravascular coagulation)
Enzyme deficient in:
1-Fructose intolerance
2-Essential fructosuria
3-Classic galactosemia
1- Aldolase B
2-Fruntokinase
3-Galactise-1-phosphate uridyltransferase
Pathology of thyroid cell with optically clear nuclei
Papillary carcinoma of the thyroid
Anemia with hypersegmented neutrophils
Macrocytic megaloblastic anemia
- B 12 deficiency
- Folate deficiency
Branching rods on oral infection
Actinomyces israelii
Most common lymphoma in USA
Diffuse large B lymphoma
Reed-sternberg cells
Hodgkin lymphoma
Lymphoma associated to EBV
Burkitt lymphoma
Hodgkin lymphoma
Burkitt lymphoma translocation
t(8;14)
Lymphoma equivalent of CLL
Small lymphocytic lymphoma
‘Starry-sky pattern” due to phagocytosis of apoptotic tumor cell
Burkitt lymphoma
Associated with Sjögren syndrome, Hashimoto thyroiditis, and H. pylori
Marginal zone lymphoma
t(11;18)
Cancer most commonly associated with a noninfectious fever
Hodgkin lymphoma
Large B cell with bilobed nuclei and prominent “owls eye inclusions”
Reed-Sternberg cells seen in Hodgkin lymphoma
Defect in platelet plug formation. Result in large platelets
Bernard-Soulier syndrome
Bone marrow filled with adipocytes and absence of splenomegaly
Aplastic anemia
CREST scleroderma
Calcinosis Raynauld phenomenon Esophageal dysmotility Sclerodactyly Telangiectasias
Penicillin mode of action
- Bind penicillin-binding proteins
- Blocks traspeptidase cross-linking of cell wall
- Activates autolytic enzymes
- bactericidal
Dermatitis, dementia, diarrhea
Niacin(B3) deficiency (Pellagra)
Red urine in the morning, fragile RBCs
Paroxysmal Nocturnal Hemoglobinuria
Cardio
Maternal lithium use
Ebstein anomaly
Cardio
Maternal alcohol use
Tetralogy of fallot
VSD
ASD
PDA
Cardio
Pregestational diabetes
Transposition of great vessels
Cardio
Congenital rubella
PDA
Pulmonary artery stenosis
DiGeorge syndrome (22q11 syndrome)
Tetralogy of fallot
Truncus arteriosus
Cardio
Turner syndrome
Coarctation of aorta
Bicuspid aortic valve
Cardio
Trisomy 21
Endocardial cushions defect(ASD,VSD)
Continuous machinery-like heart murmur
PDA
“Boot shaped heart”
Tetralogy of fallot
RVH in adult
Rib notching
Coarctation of aorta
Most common congenital cardiac anomaly
VSD
Most common congenital cause of early cyanosis
Tetralogy of fallot
