Mix Qs Flashcards
Pathology in pronator Teres Syndrome
Entrapment of the Median nerve at the pronator teres and beneath the FDS
Grocery bag neuropathy
Carrying bag with arm flexed
Pronator Teres Syndrome
Describe severity of carpal tunnel syndrome As to: Mild Moderate Severe
Mild-prolongation of SNAPS w/ slight attenuation
Moderate- both SNAPS are slowed with prolonged median latency
Severe- moderate + absent SNAPs and prolongd or absent CMAPs + fibrillation potentials in thenar muscles
Anterior Interosseus Syndrome. Is it purely motor? Purely sensory? Or mixed?
Purely Motor
Abnormal ‘ok sign’ with weakness of FPL and FDP
Anterior Interosseus Syndrome
Possible location of radial nerve compression/neuropathies
- Axilla
- Spiral groove
- Posterior Interosseous nerve compression
- Wrist (Wartenberg syndrome or handcuff neuropathy
Saturday night palsy or honeymooner palsy
Nerve affected
Location of compression
Radial nerve at the spiral groove
Associated with Monteggia fracture or fall with outstretched hand presenting with weakness of MCP and wrist extension with preserved IP extension
Radial Neuropathy with posterior interosseus nerve compression
Muscles spared in posterior interosseous syndrome
Brachioradialis and ECRL
Types of ulnar nerve compression at the Guyon’s canal at the wrist with presenting symptoms
Type 1 hypothenar and deep ulnar branch Type 2 deep ulnar branch-hypothenar spared Type 3 superficial ulnar sensory branch Painless wasting of hand muscles Intrinsic muscle atrophy
Possible locations of entrapment neuropathies of the median nerve
- At the wrist-Carpal Tunnel Syndrome
- At the forearm:
Pronator Teres Syndrome
Anterior interosseous syndrome (kiloh-nevin
syndrome)
Beneath the ligament of Struthers
Pathology of posterior interosseous syndrome?
Entrapment of the radial nerve with a fibrous band at the origin of the supinator muscle or otherwise known as the arcade of Frohse
What nerve and and the location of the entrapment in Wartenberg Syndrome
Radial nerve at the wrist. No motor weakness
Diagnostic Criteria for ALS
EL ESCORIAL WITH AWAJI MODIFICATION
A. Presence of lower motor neuron degeneration by clinical, electrophysiologic or neuropathologic examination
B. Presence of upper motor neuron degeneration by clinical exam
C. Progressive spread of sympt9ms or signs within a region or to other regions
With
Absence of EDX or pathologic evidence of other disease process
Neuroimaging evidence of other disease
Diagnostic categories of ALS
Clinically definite- clinical or EDX evidence by the presence of LMN and UMN signs in the bulbar region and atleast two spinal regions or the presence of LMN and UMN signs in 3 spinal regions
Clinically probable-UMN and LMN signs in atleast 2 regions with some UMN signs rostral to the LMN signs
Clinically possible- UMN and LMN found only in one region or UMN signs found in two or more regions or LMN signs found rostral to UMN signs
Medical treatment that slow progression of ALS
Riluzole- inhibits the presynaptic release of glutamate-> glutamate toxicity is thought to contribute to neuronal death in ALS
When to initiate Mech Vent Support in Patients with GBS?
When Vital capacity falls below 20ml/kg
What are the 3 types of Diabetic neuropathy?
- Demyelinating, symmetric, distal sensorimotor polyneuropathy
- Demyelinating asymmetric proximal polyneuropathy or diabetic amyotrophy
- Focal neuropathy-median, ulnar and peroneal nerves commmonly affected
CSF analysis findings in patients with GBS
Albuminocytologic dissociation or elevated CSF protein but with normal WBC level
3 subtypes of GBS
AIDP-mc
AMAN
ASMAN
Miller-Fisher
Triad of Miller-Fisher Variant of GBS
Ataxia
Areflexia
Opthalmoplegia
Dose of IVIG treatment for GBS
0.4/kg daily for 5 consecutive days
Most common organism responsible for GBS
Campylobacter Jejuni
Triad of Wernicke Syndrome
Ataxia, dementia, opthalmoplegia
Nerve most commonly affected by lead toxicity
Radial nerve, presenting as wrist drop or weakness in wrist extension
Most common mass affecting the brachial plexus
Lung
Breast
Lymphoma
What part of the brachial plexus is affected in Pancoast Tumor?
Lower trunk associated with Horner’s Syndrome
S/sx of Acute Brachial Neuritis or Parsonage-Turner Syndrome?
Severe pain in the shoulder blade, upper arm or neck followed by weakness of the muscles of the shoulder girdle 2 weeks after.
Antecedent events causing Parsonage-Turner Syndrome
Immunization
Infections
Surgery
Pregnancy
What part of the brachial plexus is affected in Acute brachial neuritis?
Upper trunk
Nerve root of lateral femoral cutaneous nerve?
L2-L3
3 components of the lateral collateral ligament of the ankle
- Anterior talofibular ligament
- Posterior talofibular ligament
- Calcaneofibular ligament
Mechanism of action of Benzodiazepines?
Enhancement of GABA inhibitory activity.
Effective for acute and chronic low back pain flr short term relief
Rapid withdrawals can cause seizures.
Not generally recommended for low back pain
Mechanism of action of Baclofen?
GABA derivative that inhibits transmission at the spinal level and brain
MOA of Dantrolene Sodium?
Blocks the calcium channels at the sarcoplasmic reticulum.
Side effect: severe hepatotoxicity
MOA of Tizanidine
Centrally acting alpha 2 agonist
Common side effects of tricyclic antidepressants?
Dry mouth, blurry vision, constipation, dizziness, tremors and urinary disturbances.
Examination maneuvers for Piriformis Syndrome
PACE maneuver- resisted abduction and external rotation of the thigh
Freiberg maneuver- forceful internal rotation of the extended thigh
Beatty maneuver- deep buttock pain on a side lying patient holding a flexed knee several inches off the table
Common pediatric PRIMARY spine malignancies
Osteoid osteoma
Osteoblastoma
Aneurysmal bone cysts
Most frequent malignant lesion affecting the pediatric spine?
Ewing’s sarcoma
Pediatric spine tumor whose pain is responsive to aspirin?
Osteoid osteoma
Describe Scheurmann disease.
Thoracic kyphosis with compensatory lumbar lordosis in pediatric population secondary to repetitive loading of the immature spine
HIV-associated spinal cord diseases
Vacuolar myelopathy- presents as incomplete spastic paraplegia with loss of proprioception and vibration sense
Human T-lymphotrophic virus type 1 causes progressive chronic myelopathy, presenting as progressive spastic paraplegia
MRI findings in transverse myelitis
Spinal cord swelling
Increased signal in T2 weighted images
Thoracic spine is most commonly affected
Most efficient wheelchair propulsion pattern?
Semicircular pattern
Most common site of fracture in patients with SCI
Supracondylar region of the femur
Medication given to reduce the incidence or postoperative recurrence of heterotopic ossification in patients with SCI
Etidronate
Most common location of heterotopic ossification in patients with SCI
Hip joint
Manifestation of cervical spondylosis
Ligamentous hypertrophy
Hyperostosis
Disk degeneration
Zygapophyseal joint arthropathy
AAP Commonly used for post TBI agitation
Quetiapine
Treatment for post TBI agitation
- Atypical antipsychotics- quetiapine
- Beta blockers- propanolol
- Benzodiazepines
Management of upper motor neuron bowel
Digital rectal stimulation
Rectal stimulant medications, enemas
electrical stimulation
GOAL: cause relaxation of the IAS and if strong enough can reflexively relax EAS
Causes of upper motor neuron bowel
Lesion above the conus medullaris at the level of T12
What is the cause of lower motor neuron bowel?
Lesions below the conus medullaris, cauda equina, pelvic surgery,vaginal delivery or chronic straining
Most important side effect of dantrolene sodium
Hepatotoxicity
Liver function test should be monitored monthly initially then several times per year
Most common diplegic gait pattern in older children with cerebral palsy
Crouch gait
Most common diplegic gait pattern in young children with cerebral palsy and is the precursor to crouch gait
Jump gait
Gait pattern associated with overactive rectus femoris in patients with hemiplegic cerebral palsy
Stiff knee gait
Most common site of Heterotopic ossification in burned individuals?
Posterior elbow in the affected side
Pattern of neuropathy in patients with deeper and larger TBSA?
Axonal rather than demyelinating
Ideally position of the hand for splinting?
Intrinsic plus position
MCP flexion with IP extension
Positioning of the hand resulting from weakness of the intrinsic and strong extrinsic muscles?
Intrinsic minus hand
2 main diseases of children for which lung transplant is performed
Cystic fibrosis
Primary pulmonary hypertension
Main reason for lung transplant in adults
COPD
Equivalent of 1 MET
3.5 ml/kg per minute
Most common feature of dermatomyositis and polymyositis?
Painless muscle weakness
Symmetrical and proximal
Distribution: neck, shoulder, pelvis and thigh
Difficulty lifting arm and climbing uphill
Most characteristic skin manifestation of dermatomyositis?
Gottron papules and heliotrope rash
Characteristic finding of inclusion body myositis?
Rimmed vacuoles
2 types of femoroacetabular impingement
CAM- femoral head-neck junction variety
Pincer- acetabular over coverage of the femoral neck
Structures of the posterolateral corner:
- LCL
- Popliteus tendon
- Posterolateral joint capsule
- Biceps femoris tendon
- Peroneal nerve
- Lateral head of gastrocnemius
- Lateral meniscus
- Posterior meniscofemoral ligament
Most common mechanism of injury of the posterolateral corner?
Strong hyperextension and varus force
2 most common types of tarsal coalition?
- Calcaneonavicular
2. Talocalcaneal
triangular fibrocartilage complex consists of?
- triangular fibrocartilage
- meniscus homologue
- extensor carpi ulnaris tendon sheath
- volar and dorsal radiocarpal ligaments.
Differential Diagnosis for MS
- Neuromyelitis optica
- Acute transverse myelitis
- Acute Disseminated encephalomyelitis
Autoimmune condition that targets the aquaporin 4 channels?
Neuromyelitis optica
Criteria for diagnosis for neuromyelitis optica
- Optic neuritis + acute myelitis
+
2 of the following:
contiguous spinal cord involvement spanning 3 spinal segments or more
Exclusion of MS
NMO IgG seropositive status
MS subtypes
- Relapsing Remitting (RRMS)
- most common subtype
- period of exacerbation ff by period of remission
- Secondary Progressive (SPMS)
- pt w/ RRMS no longer has exacerbations but w/ persistent accumulation of disability
- Primary progressive (PPMS)
- affects males and females equally
- lack exacerbation but w/ accumulation of disability over time
- Progressive Relapsing (PRMS)
- least common and most aggressive
- assoc w/ high mortality
Diagnostic Criteria for Multiple sclerosis
McDonald’s Criteria MRI based on
Dissemination in Space
Dissemination in Time
Uhthoff phenomenon
Transient blindness or blurring of vision in patients with MS after exposure to heat e.g warm baths
What is the Karvonen formula?
target training HR = resting HR + (0.6 [maximum HR -resting HR])
Computes for the maximum heart rate
VO2Max
O2 consumed in liters/min
Or
ml/kg/min
Best evaluation/test for evaluation of the capacity to exercise in cardiac and pulmonary conditions
Cardiopulmonary exercise test CPET
Karvonen Equation used to estimate target heart rate
Target HR= (max HR-resting HR) x % intensity + resting HR
Stroke volume
Volume of blood ejected with each left ventricular contraction
Achieve max at 40% VO2
Cardiac output
HR x SV
Primary determinant of VO2max
Phases of throwing where majority of injuries occur?
- Late cocking phase- phase where extreme ER occurs
2. Deceleration phase
Independent predictors of vascular disease?
- Cigarette smoking
2. Diabetes
Marker of peripheral artery disease/ implicated in PAD?
Elevated homocysteine levels
Primary mechanism of injury in stingers?
Brachial Plexus tensile overload
Cause of brachial plexus tensile i juries in younger athletes?
Forceful contralateral neck lateral bending with ipsilateral shoulder and arm depression
Weak neck and shoulder girdle
Only muscle in the hamstrings group innervated by the common peroneal nerve?
Short head of the biceps femoris
Cause of stingers in older athletes?
Cervical root compression due to forceful cervical extension and rotation resulting un narrowing of the neuroforamen
Mainstay of pharmacologic therapy in Exercise-induced bronchospasm?
Short-acting beta agonist 15 mins before exercise
3 most common causes of anemia in the athlete
Iron- deficiency anemia- menstruating athlete
Physiologic anemia- MC in endurance athlete
Foot strike hemolysis-RBC destruction in the feet
Female athlete triad
Anorexia
Amenorrhea
Skeletal demineralization
Calcium and Vit. D recommended dose per day?
Calcium- 1200 to 1500 mg
Vit. D- 400 to 800 IUs per day