MITRAL VALVE PROLAPSE Flashcards

1
Q

4 other terms for MVP

A

a. Systolic click-murmur syndrome
b. Barlow’s syndrome
c. Floppy-valve syndrome
d. Billowing mitral leaflet syndrome

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2
Q

Most common abnormality leading to primary MR

A

MVP

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3
Q

One of the causes of MVP is the peduction of production of what type of collagen?

A

III

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4
Q

MVP is a frequent finding in patients with heritable disorders of connective tissue, such as: (3)

A

a. Marfan syndrome
b. Osteogenesis imperfecta
c. Ehlers-Danlos syndrome

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5
Q

Which mitral leaflet is mostly affected in MVP

A

Posterior mitral leaflet

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6
Q

MVP is more common in what population (gender and age group)?

A

a. Women

b. Ages of 15 and 30 years

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7
Q

In older (>50 years) patients, MVP is more common in what gender?

A

Men

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8
Q

Mid- or late-(nonejection) systolic click is seen in what valvular abnormality?

A

MVP

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9
Q

Systolic click followed by a high-pitched, mid-late systolic crescendo–decrescendo murmur is a feature of

A

MVP

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10
Q

Leaflet involved in MVP when the radiation of the murmur is to the base of the heart

A

Posterior leaflet prolapse (Jet of MR is directed anteriorly)

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11
Q

Leaflet involved in MVP when the radiation of the murmur is to the axilla and the back

A

Anterior leaflet prolapse (Jet of MR is directed posteriorly)

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12
Q

Earlier with standing, MVP murmur is increased or decreased?

A

Increased

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13
Q

During the train phase of the Valsalva maneuver, MVP murmur is increased or decreased?

A

Increased

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14
Q

During any intervention that decreases LV volume (preload), MVP murmur is increased or decreased?

A

Increased

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15
Q

During squatting, MVP murmur is increased or decreased?

A

Decreased

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16
Q

During isometric exercises, MVP murmur is increased or decreased?

A

Decreased

17
Q

Indications for MVP repair (5):

A

a. Symptomatic severe MR
b. LV systolic dysfunction
c. Pulmonary artery hypertension
d. Recent onset AF
e. Flail mitral leaflet

18
Q

Can be considered for treatment of symptomatic patients at high surgical risk with severe primary MR due to MVP

A

Transcatheter edge-to-edge repair