Mitosis puntos de control Flashcards

1
Q

Celulas labiles

A

en constante cambio y divison

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2
Q

celulas quisantes

A

solo en momentos determinados se van a dividir (higado, páncreas, astrocitos) en procesos de daño

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3
Q

Células post-mitoticas

A

no se pueden dividir nunca más (neuronas, cardíacas, lobocito, eritrocitos )

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4
Q

Fase G0

A

Fase fuera de la división donde no se dividen

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5
Q

Que tipos de celulas pueden estar en fase G0

A

celulas quisantes y celulas post-mitoticas

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6
Q

fases de la interfase

A

G1
S
G2

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7
Q

Tipos de factores

A

Internos y externos

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8
Q

Tipos de factores internos

A

Inductores e inhibidores

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9
Q

CDK esta activa o inactiva

A

inactiva

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10
Q

que activa a CDK

A

ciclina

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11
Q

Tipos de CDK

A

CDK-G1S
CDK-G1/S
CDK-S
CDK-M

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12
Q

Mediante que inducen los cambios las CDK

A

fosforilaciones

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13
Q

que es un CKI

A

un complejo inhibidor

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14
Q

Tipos de CKI

A

CIP (inhiben a todas los CDK)
-p21
-p27
INK
-p16(solo inhibe a CDK4 y 6)
p53: para daño de ADN
Rb: inhibe a EF2

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15
Q

trabajo de la cdk-G1

A

activar la sintesis de ADN

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16
Q

que ciclina compone a CDK

A

Ciclina D
+
CDK4,6

17
Q

quien es el responsable de activar a la ciclina A y E

A
18
Q

3 puntos de control

A

en
G1: verificación no daños en ADN
G2: verificación de buena replicación
M: que todos esten unidos al uso mitotico