Mitosis & Meiosis (Chapter 3) Flashcards
Chromosome Theory of Inheritance
-Describes how the transmission of chromosomes account for mendelian patterns of inheritance.
-Established how chromosomes carry and transmit genetic determinants of traits
The three lines of scientific inquiry unfolded through the chromosome theory of inheritance:
- Analysis of the transmission of traits from parents to offspring
- Inquiry into the basis of heredity
- Microscopic examination of the processes of mitosis, meiosis and fertilization.
The chromosome theory of inheritance is based on the following fundamental principles:
- Chromosomes contain genetic material
- Chromosomes are replicated and passed from parent to offspring
- The nuclei of most eukaryotic cells contain chromosomes that are found in homologous pairs, called diploids
- During the formation of gametes, different types of chromosomes segregate independently.
- Each parent contributes one set of chromosomes to its offspring, each set being a full complement of genes.
Chromsomes are:
Structures within living cells that contain the genetic material, containing genes
Chromosomes are composed of:
-DNA, the genetic material
-Proteins, providing the organized structure of the chromosome
(DNA-protein complex is called chromatin)
Chromosomes in Bacterial Cell:
-Contain a single circular chromosome, found in the nucleoid with the cytoplasm/no nucleus
- Cytoplasm enclosed by a plasma membrane, regulating nutrient uptake and waster excretion
-The rigid cell wall outside the membrane protect the cell from breakage.
Chromsomes in Eukaryotic Cells:
-Nucleus contains the genetic material, having multiple chromosomes and 2 membranes
- Mitochondrion is where Respiration/ATP Synthesis occur, containing genetic material/DNA
-Centriole responsible for organization of spindle fibers
-Protein Synthesis occur in the RER(Rough endoplasmic reticulum)
Ploidy:
Refers to the number of copies each chromosome has in a cell:
-Haploid(n)-one copy
-Diploid(2n)-two copies
-Triploid(3n)- three copies
Humans have a total of 46 chromosomes(23 chromosomes per set)
Biparental inheritance
For each chromosome pair, one chromosome comes from each parent.
These chromosomes are homologues/homologous chromosomes
Cytogenetics:
-Microscopic examination of chromosome, allowing detection of abnormal chromosome structure or number, distinguishes between two-closely related species.
Animal Cells are of two types:
-Somatic cells(Diploid)
Body cells, not including gametes
-Germ cells(Haploid)
Gametes-sperm and egg cells.
Karyotype
-An organized representation of chromosomes within a cell
Homologous Chromosomes
Two chromosomes in a homologous pair(homologs)
-Evolutionarily related
-Nearly identical in size
-Same banding pattern and centromere location
-Have the same genes, but it is not guaranteed they have the same alleles.
Sex chromosomes (X and Y) are homologous meaning:
-Sex chromosomes behave as homologs in meiosis
-Related but there are drastic changes that have accumulated over time,
-Differ in size and genetic composition
-Short regions of homology
-Inherited as a pair
Importance of Cell Division:
–Purpose of cell devision is asexual reproduction, the same process some unicellular organisms go through to produce new individuals.
–Cell Division allows for multicellularity, we are all derived from a single cell that has undergone repeated cell division.