Mitosis & DNA replication Flashcards
Steps of DNA replication
Step 1 - The DNA of the double helix unzips meaning each base splits from its complementary pair. This occurs due to an enzyme It leaves all of the bases exposed.
Step 2 – A specialised enzyme begins to attach free bases with the exposed bases on each strand of the DNA helix. They follow the complementary base pairing rules.
Step 3 – The result is now two double helix strands which are completely identical to each other.
At the end of DNA replication, each strand of the replicated chromosome is called a “Chromatid”. They are joined in the centre by a structure called a “Centromere”. Now that the DNA in the cell has replicated, the cell is now ready to divide into two new cells. This cell division process called “Mitosis”.
Base pairing rules
A = T
G = C
Apple in Tree
Car in the Garage
Interphase
Chromosomes are copied and they appear as thread like coils
Prophase
Mitosis beings, centrioles appear and begin to move to opposite ends of the cell, and spindle fibres form between the poles. Chromosomes appear, thicken and shorten.
Metaphase
Chromosomes line up at the spindle fibres at the equator of the cell, and the centromere of the chromosomes attach to the spindle fibres.
Anaphase
The chromatids separate at the centromere, and are again known as chromosomes. The chromosomes are pulled apart and move to opposite ends of the spindle.
Telophase
Two new daughter cells are formed and cell division ends. 2