Mitosis Flashcards

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1
Q

Importance of mitosis

A
  • Mitosis ensures that both daughter cells produced when a parent cell divides are genetically identical.
  • Needed for growth of multicellular organisms and for repairing damaged tissues.
  • Some animals, plants and fungi also use it to reproduce asexually.
  • PMAT+C (Prophase, Metaphase, Anaphase, Telophase + Cytokinesis)
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2
Q

Chromosomes

A
  • Before replication, 1 chromosome has 1 chromatid (strand).
  • After replication, chromosome has 2 chromatids.
  • Centromere is the middle region where 2 chromatids are joined together.
  • 2 strands on the same chromosome are called sister chromatids.
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3
Q

Prophase

A
  1. Chromosomes condense, getting shorter and fatter.
  2. Centrioles start moving to opposite ends of the cell, forming a network of protein fibres across it called the spindle.
  3. Nuclear envelope breaks down and chromosomes lie free in cytoplasm.
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4
Q

Metaphase

A
  1. Chromosomes line up on the spindle equator and become attached to spindle by their centromere.
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5
Q

Anaphase

A
  1. Centromeres divide, separating each pair of sister chromatids.
  2. Spindles contract, pulling chromatids to opposite ends of the cell, centromere first.
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6
Q

Telophase

A
  1. Chromatids reach opposite poles on spindle.
  2. They uncoil and become long and thin again.
  3. They’re now called chromosomes again.
  4. A nuclear envelope reforms around the 2 groups of chromosomes.
  5. So there are 2 nuclei.
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7
Q

Cytokinesis

A
  1. The cytoplasm divides.
  2. In animal cells a cleavage furrow forms around the middle of the cell.
  3. There are now 2 daughter cells that are genetically identical to the original cell and to each other.
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8
Q

Investigating mitosis

A
  1. Stain the chromosomes so you can see them under a microscope. This allows you to see what happens during mitosis.
  2. Make a squash microscope slide. Squashes can be made by treating the root tips with hydrochloric acid.
  3. Add stain and then physically squish cells beneath cover slip.
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