Mitosis Flashcards
What is Cell Division
The process by which a parent cell divides into 2 or more daughter cells.
What is a chromosome?
It is a single coiled DNA molecule containing many genes.
What are genes?
Genes are sections of DNA that encode genetic instructions.
How many chromosomes are there per cell?
A normal body cell will contain 46 (23 pairs) of chromosomes. This number is the diploid (2n) number of chromosomes. A gamete (sex cell) will contain only 23 chromosomes. This number is the haploid (n) number of chromosomes.
What happens during interphase?
- Cell grows, stores energy and duplicates organelles.
- The DNA replicates and the DNA content of the cell doubles. The chromosome number still remains 2n.
- The 2 identical chromatin threads are joined together at the centromere. They are called sister chromatids.
- The chromatin threads are in the dispersed state.
What happens during prophase?
- The chromatin condenses to form chromosomes, which are visible under the light microscope.
- The nuclear envelope and nucleolus disappears.
- Asters, which are structures made of microtubules, form around the centrioles.
- The 2 centrioles move apart to opposite sides of the cell.
- Spindle fibres extend from one pole of the cell to the other.
What happens during metaphase?
- The chromosomes line up along the metaphase plate, which is equidistant from the 2 poles.
- The centromere of each chromosome is attached on both sides to a spindle fibre.
What happens during anaphase?
- Each pair of sister chromatids split at the centromeres and are pulled to opposite ends of the cell as the spindle fibres shorten. Each chromatid is now called a daughter chromatid.
- The opposite ends of the cell move further apart.
- The 2 ends of the cell now have identical collections of chromosomes.
What happens during telophase?
- Spindle fibres break down.
- Daughter nuclei begin to form at both ends of the cell - nuclear envelope and nucleolus reform.
- Each daughter chromatid uncoils to form chromatin threads.
What happens during cytokinesis?
- The 2 daughter cells are pinched apart.
- Each daughter cell is a copy of the parent cell.