MITOCHONDRIAL

Question 1

LEBER HEREDITARY OPTIC NEUROPATHY (LHON)

Answer 1

Vision clouding and blurring&raquo_space; severe loss of visual acuity and color vision&raquo_space; permanent and profound central vision loss (detailed vision); Bilateral; Cell death in the optic nerve; Genetics: Mitochondrial inheritance: Only passed on from mother, MT-ND1, MT-ND4, MT-ND4L, MT-ND6; Significant number of people never show signs or symptoms of LHON