Mistakes Flashcards
What is power (stats)?
The probability of detecting a statistically significant difference
When is a Student’s paired t-test used?
When comparing related or matched samples, or repeated measurements on a single sample i.e. patients cholesterol before and after receiving a lipid lowering therapy. the measurements are taken from the same individuals§
What respiratory physiological change may be expected from multiple PEs
Reduced TLCO - recurrent PE can cause areas of lung to be poorly perfused and ventilated
What is a Holmes-Adie Pupil?
A benign condition seen in women. It is a common differential for a dilated pupil
What is associated with Holmes-Adie puils?
Dilated pupil, females, absent leg reflexes
Unilateral in 80%
What is conduction aphasia?
where speech is fluent but repetition is poor. Comphrehension is relatively intact
What type of infarct is conduction aphasia associated with?
Arcuate fasciculus in dominant hemisphere - between wernickes and brocas area
Equation for Absolute Risk Reduction
Absolute risk reduction = control event rate - experimental event rate
What do prominent v waves on JVP represent?
tricuspid regurgitation
Which HLA is Sjogren’s syndrom associated with?
HLA-DR3
What bacteria are most common cause of neutropaenic sepsis?
staph epi and gram positive, coagulase negative bacteria
Which diabetic medication can cause a B12 deficiency?
Metformin - alters small bowel motility
What part of the cell cycle, G1, M, G2, S, does Vincristine act on?
M - inhibits tubulin polymerisation and spindle formation
What additional treatment should be given to those with meningeal tuberculosis
Prednisolone
What is vitamin C also known as?
Ascorbic acid
What monitoring is required for starting hydroxychloroquine?
Visual acuity and fundoscopy - may result in severe and permanent retinopathy
What antibiotic is given for tetanus?
Metronidazole
What does the presence of DIC without any underlying cause in a young patient suggest?
Acute promyelocytic Leukaemia
What chromosome translocation is associated with acute promyelocytic leukaemia?
T15:17
What condition is associated with bilateral vestibular schwannomas?
NFM type 2
Where is glucose reabsorbed in the kidney?
Proximal convuluted tubule
Weakness of the deltoid and biceps muscle suggests injury to which brachial plexus nerve?
C5
Which blood pressure medication can interfere with testing for primary hypoaldosteronism (Conn’s syndrome)?
Ramipril/ ACEi’s - interferes with the RAAS system
What can high urea levels indicate?
An Upper GI bleed
