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Rheumatology (Long) > Miscellaneous > Flashcards

Miscellaneous Flashcards

1
Q

MCTD - overlapping features of which conditions?

A

SLE, polymyositis and systemic sclerosis.

Anti-U1 RNP +ve (100%)

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2
Q

Major cause of mortality in MCTD?

A

PAH

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3
Q

MCTD: pharmacological tx? (4)

A

Steroids

NSAIDs

Hydroxychloroquine

Immunosuppression (Cyclophosphamide for PAH)

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4
Q

Abs to test in Systemic sclerosis? (6)

A

ANA (90%)

Anti-centromere (limited)

Anti-Scl70 (diffuse)

Anti-RNP (dcSSc, PAH, myositis)

Anti-PM-Scl (myositis)

Anti-Th/To (lsSSc, PAH)

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5
Q

Abs associated with polymyositis and dermatomyositis? (3)

A

Anti-Jo-1

Anti-Mi2

Anti-SRP (aggressive disease)

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6
Q

Ab associated with ITP?

A

Anti-Gp IIb/IIIa (sensitivity 80%, specificity 90%)

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Rheumatology (Long) (11 decks)

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