Misc Resp Meds

Question 1

Bronchodilators: Albuterol (Salbutamol)

Answer 1

a selective beta-adrenergic agonist; relaxes smooth muscle; bronchodilitation, drives K+ intracellularly

Question 2

Racemic Epinepherine

Answer 2

Stimulates both alpha- and beta-adrenergic receptors; acts on vascular smooth muscle to produce vasoconstriction, which decreaes blood flow at the capillary level-shrinking upper respiratory mucosa and reducing edema; useful in patients with postextubation stridor

Question 3

IPB-Ipatropium Bromide (atrovent)

Answer 3

may be used in combination with albuterol in the management of CLD; rationale for use in NN with CLD is due to the presence of functional muscarinic receptors in premature infants; bronchiodilitation in infants with BPD, ; decreases respiratory resistence; combination of IBP and albuterol achieved the greatest decrease in resp system resistence with increases in compliance in ventilated patients with BPD

Question 4

Inhaled Steroids

Answer 4

use in not evidence based

Question 5

iNO

Answer 5

Direct pulmonary vasodilator, Potent, selective, sustained pulmonary vasodilitation decreasing pulmnary vascular resistance and improving oxygenation; usual starting dose is 20 ppm