Misc genetic abnormalities

Question 1

What type of genetic condition is cystic fibrosis?

Answer 1

An autosomal recessive condition

Question 2

If two unaffected parents’ first child has cystic fibrosis what is the likelihood their second child will have cystic fibrosis?

Answer 2

25%

Question 3

Dysfunction in what membrane component is responsible for the symptoms of cystic fibrosis?

Answer 3

The CF transmembrane conductance regulator chloride channel

Question 4

What are the four main organisms that colonise CF patients?

Answer 4

Staphylococcus aureus, Pseudomonas aeruginosa, Burkholderia cepacia and Aspergillus