Misc BOC Questions

Question 1

Uric acid is the final breakdown of what two purines?

Answer 1

Adenine and gaunine

Question 2

A hapten can BEST be described as:

Answer 2

A nonimmunogenic material capable of stimulating an immune response only when bound to a carrier protein

Question 3

Which casts might be found in the urine of a healthy individual after strenuous exercise?

Answer 3

Hyaline and granular casts

Question 4

At a minimum, the following class of biological safety cabinet (BSC) must be used when manipulating potential bioterrorism agents and if aerosols are likely:

Answer 4

Class 2 BSC

Question 5

What ribosomal subunit is is used to ID fungus?

Answer 5

28S

Question 6

What ribosomal subunit is used to ID bacteria?

Answer 6

16S

Question 7

ACTH controls which step of steroid hormone production?

Answer 7

First step (cholesterol esters to cholesterol)

Question 8

While lead distributes to all tissues, the central nervous system, kidney, and bone marrow are particularly susceptible to lead toxicity, T or F?

Answer 8

True

Question 9

Whole blood lead measurement is the best test for detecting lead toxicity, T or F?

Answer 9

True

Question 10

Serum lead level is a good inexpensive screening test for lead toxicity, T or F?

Answer 10

False

Question 11

Lead levels below 5 ug/dL in children do not prompt ongoing monitoring, T or F?

Answer 11

True

the upper limit for monitoring is 5 ug/dL; goal is to keep below 10 ug/dL

Question 12

A Bombay individual’s blood specimen can be differentiated from a blood specimen of a group O person by which of the following?

Answer 12

Testing with anti-H lectin (Ulex europaeus)

Question 13

What is the pathogenic anaerobic bacteria is MOST frequently isolated in clinical laboratories?

Answer 13

B. fragilis

Question 14

A filarial nematode = These worms average 250 µm in length and commonly migrate through sub-cutaneous tissue, particularly in the thin skin below the conjunctival lining of the eye, resulting in a condition known as “Calabar swelling”. What is the identification of this species that presents with nuclei seen in the tail section?

Answer 14

Loa Loa

Question 15

A filarial nematode that is distinctive for the extension of two nuclei into the tail section of the adult worm, separated from one another by an open space. The adult worms more inhabit the lymphatics of the inguinal region resulting in swelling below the knee, a condition known as elephantiasis.

Answer 15

Brugia malayi

Question 16

A filarial nematode that is identified by the absence of nuclei extending into the tip of the tail. The lymphatics of the inguinal region are more commonly involved, and the worm is sheathed.

Answer 16

Wuchereria bancrofti

Question 17

After frozen RBC’s have been thawed and washed, they must be used within how many hours?

Answer 17

24

Question 18

Vitamin D is controlled by which hormone in a negative feedback loop?

Answer 18

PTH

Question 19

Which hormone produced by the thyroid gland acts to decrease calcium levels?

Answer 19

Calcitonin (keeps it in the bones)

Question 20

Which enzyme is responsible for the rate-limiting step of hormone synthesis?

Answer 20

CYP450

Question 21

For which determination is the brilliant cresyl blue stain used MOST often?

Answer 21

Retics

Question 22

A transfusion-related death must be reported to the FDA within 24 hours of the patient’s death. T or F?

Answer 22

False

Question 23

The initial notification to the FDA of a transfusion-related death must be made by fax, telephone, express mail, or electronically as soon as possible after the death is confirmed to be associated with the transfusion. T or F?

Answer 23

True

Question 24

What are possible causes of failed internal control when running qPCR?

Answer 24

• Sample have high viral loads
• Forgetting to add the internal control into the Master Mix
• Amplification did not occur

Question 25

What is the lower reference range for sperm concentration?

Answer 25

15x10^6 spermatozoa / mL

Question 26

Normal CSF glucose?

Answer 26

45-100 mg/dL

Question 27

Normal CSF protein?

Answer 27

15-50 mg/dL

Question 28

Diagnosis sensitivity is increased by assaying both amylase and lipase. T or F?

Answer 28

True

Question 29

Amylase and lipase are as predictive in chronic as in acute pancreatitis. T or F?

Answer 29

False

Question 29

Amylase and lipase are as predictive in chronic as in acute pancreatitis. T or F?

Answer 29

False

Question 30

Urinary amylase: creatinine ratio is the most sensitive test for acute pancreatitis. T or F?

Answer 30

True

Question 31

Serum lipase peaks at 24 hours after an episode of acute pancreatitis and remains high for 7-8 days. T or F?

Answer 31

True

Question 32

What initiates the classic complement pathway?

Answer 32

Binding of complement protein (C1) complex to Abs bound to an antigen-antibody complex

Question 33

What initiates the alternative complement pathway?

Answer 33

Viruses, bacteria, fungi, tumor cells, and other foreign substances

Question 34

Blood donor criteria for diastolic BP?

Answer 34

Less than 100 mm Hg

Question 35

Blood donor criteria for hemoglobin?

Answer 35

Greater than or equal to 12.5 g/dL

Question 36

Blood donor criteria for pulse?

Answer 36

50-100 bpm

Question 37

Blood donor criteria for temp?

Answer 37

At or below 37.5C (99.5)

Question 38

What serum analyte can be used to diagnose prostate cancer?

Answer 38

Acid phosphatase

Question 39

What antimicrobial is Leuconostoc intrinsically resistant to?

Answer 39

Vancomycin

Question 40

The most significant class of microbial targets for Natural Killer (NK) cells is:

Answer 40

Viruses