Misc Flashcards
What cell type is associated with clear cell adenocarcinoma?
Hobnail (large cells with clear cytoplasm)
What are the types of germ cell tumors?
Tertoma, dysgerminoma, endodermal sinus tumor, choriocarinoma
What are the sex cord stromal tumors?
Fibroma, granulosa-theca cell tumor, sertoli-leydig cell
What cells are associated with endodermal sinus (yolk sac) tumor?
Schiller-Duval bodies
What cells are associated with granulosa cell tumors?
Call-Exner bodies. Coffee bean nuclei.
What % of complete moles go on to become GTN?
~20%
What % of partial moles go on to become GTN?
~5%
What cells are found on histology with dysgerminomas?
Fried egg cells
What tumor marker is associated with dysgerminomas?
LDH
What histology finding is associated with yolk sac tumors?
Schiller-Duval Bodies. (resemble a glomerulus)
What’s the tumor marker in choriocarcinoma?
hcg
Bleomycin toxicity?
Pulmonary fibrosis
Cyclophosphamide toxicity?
Hemorrhagic cystitis. Give means to treat toxicity
Cisplatin toxicity?
Ototoxicity
Nephrotoxicity (give fluids and amifostine to treat)
Doxorubicin toxicity?
Cardiotoxicity (give dexrazoxane to limit toxicity)