Misc Flashcards

1
Q

Name causes of eosinophilic lung disease

A

Nitrofurantoin, imipramine, sulphasalazine

Aspergillosis

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2
Q

Causes of ILD (broad categories)

A
Idiopathic pulmonary fibrosis
Rheumatological disease
Eosinophilic lung disease
Vasculitis
Inhaled agents (EAA, asbestosis, silicosis, beryliosis)
Drugs
Radiation
Sarcoidosis 
TB
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3
Q

What are the drug causes of ILD?

A
Amiodarone
Nitrofurantoin
Busulphan
Bleomycin
Gold
Methotrexate
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4
Q

Causes of apical lung fibrosis

A
Berylliosis
Radiation
EAA 
ABPA
Sarcoidosis
TB
Silicosis

Coal workers pneumoconiosis
Langerhans cell histiocytosis
Ankylosing spondylitis
Psoriasis

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5
Q

Causes of basal lung fibrosis

A
IPF
Rheumatological diseases (except AS and psoriasis)
Connective tissues diseases
Drugs
Asbestosis
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6
Q

Possible drug treatments of idiopathic pulmonary fibrosis?

A

Nintedanib

Pirfenidone

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7
Q

Most common pathogens in IECOPD?

A

Streptococcus pneumoniae
Haemophilus influenzae
Moraxella catarrhalis

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8
Q

What do you send pleural fluid for?

A

Protein and LDH - Lights criteria
pH and glucose - low in malignancy, empyema, TB, RA, SLE
Amylase - for pancreatitis, malignancy and oesophageal rupture
Cholesterol - for chylothorax
Cytology
MC&S
Ziehl Neelson stain and mycobacterium culture
RF and ANA if AI disorder suspected

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9
Q

Causes of bronchiectasis

A

Respiratory childhood infections (pertussis, measles, TB)
Bronchial obstruction (ca, chronic aspiration, FB, LN)
Fibrosis
Muco-ciliary clearance defects (CF, Kartageners)
Immunodeficiency
ABPA
Autoimmune disease
Idiopathic

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10
Q

What are the extrapulmonary manifestations of mycoplasma pneumonia?

A
Neuro - aseptic meningitis, encephalitis, transverse myelitis, GBS, neuropathy
Cardiac - myocarditis, pericarditis
Rheum - arthralgia, myalgia, myositis
Haem - thrombocytopenia, cold AIHA, DIC
GI - D, V, hepatitis, pancreatitis
Derm - EN, EM, SJS
Endo - SIADH
Renal - GN, interstitial nephritis
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11
Q

How do you classify aortic stenosis?

A

By AV area (severe <1cm)

By pressure gradient (severe >50mmHg)

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12
Q

What is Heyde’s syndrome?

A

Increased risk of GI bleeding from angiodysplasia in presence of AS
Due to activation of vWF as it passes through tight valve under sheer stress -then is rendered inactive hence bleeding in gut

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