Minor illnesses Flashcards

1
Q

Sinusitis cause

A

Often post-URTI - Oedema + reduced cilia action - secondary bacterial infection. Polyps + septal deviation more risk as less drainage & higher risk in smokers as irritated mucosa + less ciliary function

H influenzae + S pneumoniae most common

Can also be S aureus, Pseudomonas, Moraxella, Fungal

Or, direct spread (dental infection, swimming), abnormal anatomy, ITU comps, systemic disease e.g. Kartagener’s

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2
Q

Sinusitis presentation

A

pain (maxillary-cheek/teeth, ethmoid-between eyes esp when bending, frontal headache), purulent rhinorrhoea, nasty taste from postnasal drip, tenderness, fever, anosmia, cacosmia (pt notices bad smell without a source), nasal congestion. Swelling uncommon-exclude cancer or dental

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3
Q

complications of sinusitis

A

pyoceles, orbital cellulitis/abscess (periorbital oedema, displaced globe, diplopia, ophthalmoplegia, reduced VA), osteomyelitis (Staph), subperiosteal abscess, meningitis/encephalitis, cerebral abscess, cavernous sinus thrombosis

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4
Q

Acute management of sinusitis

A

1 week to 1 month of Sx. Majority due to a virus and takes on average 2.5w to resolve (even if bacterial)
Adv para/ibu for sx, if systemically unwell give 5d of co-amoxiclav, if lasting >10d + severe sx then give phenoxymethylpenicillin.

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5
Q

Chronic sinusitis management

A

lasting >3 months, often S aureus/anaerobes. Adv it is a natural course, treat any allergic rhinitis/asthma/dental issues, simple analgesia, occasional intranasal decongestion for max of 1w, warm face packs, consider up to 3m of intranasal corticosteroids

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6
Q

What is not recommended for sinusitis?

A

antihistamines (unless already have allergic rhinitis, cos they thicken the mucus so makes it worse), steam inhalation (burns risk), oral steroids, mucolytics

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7
Q

Differentials for sore throat

A
  • Pharyngitis
  • Tonsillitis: often viral/even if bacterial with S pyogenes most common it usually resolves just a couple of days longer. Fever-PAIN score, if 4/5 give Abx, if 2/3 consider delayed prescription. Phenoxymethylpenicillin/macrolide if allergy. Nb there are also loads of rare causes of tonsillitis which you may suspect in immunocompromised pt
  • EBV - causes tonsillitis, adenopathy. Abstain from contact sports for 8w
  • Hand foot + mouth - a/w vesicles. Coxsackievirus
  • Measles
  • Scarlet fever - toxin produced by certain Strep in tonsillitis causes scarlatina rash + strawberry tongue
  • otitis media-referred pain
  • peri-tonsillar abscess
  • acute epiglottis (HiB, v ill, don’t examine throat until hospital as can cause full obstruction)
  • acute laryngitis: more in adults, complication of viral URTI esp para-influenza. Inflammatory oedema - hoarse voice, barking cough, stridor. may give steroids
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8
Q

Chest infection

A
  • Acute bronchitis - transient inflammation of trachea + bronchi a/w mucus + oedema. Usually viral. Self-limiting but cough often lasts 3w. M-analgesia, fluids, stop smoking, hot water/honey + lemon may soothe throat, OTC stuff not recommended, consider Abx only if systemically unwell/high risk of complications, would use amoxicillin or doxycycline if allergic
  • CAP: acute infection of parenchyma most commonly S pneumoniae, outbreaks of H influenza + Mycoplasma. Use CRB-65 to see if need hospital& general condition. CRB0/1 may treat at home but if sats<94% deffo send in. If >60+smoker do CXR to r/o cancer. Give amoxicillin +/- clarithro (or doxy if pen allergy)
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9
Q

Causes of UTI

A

GI organisms from retrograde spread/blood/direct (catheter/surgery). Organisms include E coli, S saprophyticus, Proteus mirabilis, Klebsiella pneumoniae

In children can also be caused by others e.g. Enterococcus

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10
Q

RF for recurrent UTI

A
  • Adult: sexual intercourse, recurrent UTIs, urinary incontinence, atrophic vaginitis, catheterisation, older men, BPH/urinary tract stones/urethral stricture, DM, immunosuppression
  • Child: <1y, female (except in first 3m), previous UTI, voiding dysfunction (structural, neurogenic bladder, withholding, chronic constipation), vesicoureteral reflux (25% of children <6y with first UTI have this), immunosuppression, no hx breastfeeding, sexual activity
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11
Q

Complications of UTI

A
  • Ascending from LUTI to UUTI – pyelonephritis, abscess, impaired renal function, renal failure, urosepsis
  • Urinary stones – Proteus infection
  • In pregnancy (UTI + asymptomatic bacteruria) – preterm delivery, low birthweight
  • Men – prostatitis
  • Children – renal parenchymal damage (after upper), hypertension
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12
Q

Differentials for people presenting with ?UTI (F, M, children)

A
  • Female: atrophic vaginitis/lichen sclerosis/lichen planus/interstitial cystitis, derm (psoriasis, dermatitis etc), spondyloarthropathies, gynae/uro cancers, STIs, trauma, ADR of drugs like cyclophosphamide/opioids/nifedipine
  • Male: acute prostatitis (fever, low back/suprapubic/perineal pain, tender on DRE), bladder/renal cancer, epididymitis (scrotal pain, oedematous), STIs, urethritis, BPH
  • Children: interstitial cystitis, Kawasaki disease, meningitis, renal stones, sepsis, threadworms (perianal itching), urethritis, voiding dysfunction, vulvovaginitis
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13
Q

Female UTI management

A

o Self-care – paracetamol, encourage fluids, cranberry doesn’t work. Safety net – return if worsen or doesn’t improve in 48h
o Abx if severe enough/risk of comps – usually nitrofurantoin MR or TMP for 3d (if TMP low risk of resistance), if not working there are other options. Could also delay for 48h. Avoid nitro if GFR<45 (it won’t work)
o If have haematuria re-test urine after the Abx
o Pregnancy UTI or asymptomatic bacteruria – nitrofurantoin (avoid at term-neonatal haemolysis), or if not amoxicillin/cefalexin. For 7d. If GBS identified needs to inform antenatal services.
o Breastfeeding – TMP/cefalexin. Avoid nitro in BF as small amounts but enough to cause haemolysis in G6PD-def infants

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14
Q

Male UTI management

A
  • Male: TMP or nitrofurantoin for 7d. Avoid nitro if GFR<45 (it won’t work)
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15
Q

Child UTI management

A
  • Children: if <3m need IV. If >3m and pyelo may need IV or give cefalexin (until culture). If lower UTI and >3m give trimethoprim or nitrofurantoin (for 3 days)
    o Arrange US KUB if atypical, recurrent or <6m old
    o Adv: bring back if not responding in 24-48h, complete course, paracetamol, fluids, encourage voiding
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16
Q

Red flags in a pt with dyspepsia

A

unintentional WL, chronic GI bleeding, progressive dysphagia, persistent vomiting, iron-def anaemia, epigastric mass; if >55 with unexplained persistent new-dyspepsia need 2ww as well

Lower threshold for referral if FH of upper GI cancer, Barrett’s oesophagus, pernicious anaemia, known dysplasia

17
Q

What are the causes of dyspepsia?

A
  • Functional (75%)
  • PUD
  • Oesophagitis
  • GORD
  • Gastritis - H pylori, viral, autoimmune, Crohn’s
  • Medications
  • Achalasia - rare, a/w CP, aperistalsis, impaired LOS relaxation
  • Oesophageal spasm - dysmotility, a/w retrosternal CP + dysphagia
  • Biliary pain
  • Cancer - oesophageal SCC, gastric adenocarcinoma
18
Q

Drug causes of dyspepsia

A

NSAIDs (reduce mucosal PGs), digoxin, Abx, steroids, iron, CCBs, nitrates, bisphosphonates

19
Q

Peptic ulcer disease

A

o Duodenal more common, gastric ulcers also. NSAIDs + H pylori main causes
o Recurrent burning epigastric pain, variable relationship with food, DU often causes nocturnal pain/pain when hungry. Antacids can help. May have N+V. GUs may cause anorexia
o M: eradicate H pylori (omeprazole + 2 Abx) or just PPI, stop NSAIDs
o Comps: haemorrhage, perforation esp DU, gastric outlet obstruction

20
Q

GORD

A

reflux of gastric acid, pepsin, bile + duodenal contents back into oesophagus, overcome LOS. Can also get regurgitation of food
o RF: pregnancy, obesity, fat/chocolate/coffee/alcohol/large meals, smoking, antimuscarinics/CCBs/nitrates, hiatus hernia
o Comps: Barrett’s oesophagus (squamous to columnar metaplasia), peptic stricture
o M: antacids, PPI, H2RA (not ranitidine now has been recall)

21
Q

Malignant causes of dyspepsia

A
  • Oesophageal SCC in upper 2/3 or adenocarcinoma in lower 1/3, progressive dysphagia, food impaction, WL, lymphadenopathy. RF for SCC are smoking, alcohol, Plummer-Vinson syndrome, achalasia, breast cancer radiotherapy/RF for AC are longstanding reflux/Barrett’s, age
  • Gastric adenocarcinoma – link to H pylori, smoking, diet, pernicious anaemia
22
Q

Management of dyspepsia

A
  • Lifestyle: WL, avoid trigger foods (commonly coffee, choc, tomatoes, fatty, spicy), eat smaller meals, eat dinner 3-4h before bed, stop smoking, reduce alcohol to recommended limits, encourage relaxation
  • Short term antacid and/or alginate but not long term (OTC)
  • Consider reducing/stopping drugs worsening sx like alpha blockers, anticholinergics, aspirin, NSAIDs, BZD, beta blockers, bisphosphonates, CCBs, steroids, nitrates, TCAs
  • Prescribe 1 month PPI initially, test for H pylori if status not known [urea breath test or stool antigen test, must not have taken PPI in past 2w]. H pylori eradication - a PPI plus amoxicillin + clarithromycin/metronidazole, for 7d
23
Q

Assessment of a pt p/w headache

A
  • History questions: SQUITARS, ass sx (nausea, photo/phonophobia, motion sensitivity, autonomic sx like ptosis/tearing), analgesic use, FH, red flag sx
  • Examination: fundoscopy (papilloedema), in older palpate temporal arteries, BP. Usually normal in primary disorders
  • Ix if suspect secondary cause/red flags
24
Q

What are the criteria for diagnosing migraine?

A
  • Headache lasting 4h to 3d if untreated
  • At least 2 out of unilateral/throbbing/mod-severe/motion sensitivity
  • At least 1 of: N/V, photo/phonophobia, normal examination, no other cause

Other sx: : usually stops normal ADLs, sleep usually helps, feel tired after, may have scalp tenderness, prefer dark quiet environments

Triggers: sleep changes, stress/letdown after stress, hormones (PMS, OCP, menopause), eating (skipping, alcohol; individual foods rarely a trigger), sensory stimuli

25
Q

Migraine with aura

A

focal neurological sx immediately preceding headache in some/all attacks lasting <1h usually. Visual is commonest (positive symptoms like zigzag lines, patches of visual loss, scotomas, hemianopia), positive sensory sx like tingling/dysphasia, can be similar to TIA. Vertigo may last for hours. Hemiplegic migraine rare type causing hemiparesis

26
Q

Management of migraine

A
  • headache diary
  • acute: simple analgesia +/- anti-emetics, triptans if not working (oral, or IN/SC if vomiting, CI in IHD/HTN/PMH stroke)
  • prophylaxis if having >1-2 per month. First line amitriptyline, may also try beta blockers like slow release propranolol, or anticonvulsants e.g. topiramate
  • don’t over-use analgesia
27
Q

Migraine in pregnancy?

A

new-onset migraine is rare, and pre-existing migraine usually improves with preg so always always always check BP + urine for PET. If it is migraine avoid drugs only paracetamol, ibuprofen okay early on but in T3 risk of premature closure of the PDA

28
Q

Tension type headache

A

mild-mod, b/l, tight band sensation, non-pulsating pressure behind eyes. No N+V/autonomic but may get photophobia, may have pericranial tenderness. Can last 30m-7d! Often a/w depression

simple analgesia (avoid overuse), physical like massage/ice packs, if opioids are needed is probs not TTH, identify sleep disorders/chronic pain. If frequent may consider migraine suppression e.g. low dose amitriptyline

29
Q

What are the trigeminal autonomic cephalgias?

A

u/l trigeminal distribution pain (usually ophthalmic) and ipsilateral autonomic features

30
Q

Cluster headache

A

mostly affects men aged 20-40y.

Recurrent bouts excruciating u/l pain behind eyes + PNS activation (red eye, tearing, nasal congestion, transient Horner syndrome), pt rock about, lasts 30-90m may occur several times per day esp at night, clusters most nights for 1-2m then stop for about a year.

M: no analgesics/anti migraine drugs help, SC/IN sumatriptan + high flow O2 can help. Avoid triggers like alcohol/smoking

31
Q

Chronic daily headache

A

headache 15+ days per month for at least 3m, majority due to migraine, medication overuse is a big cause, explain about this + transient rebound sx as withdraw meds

32
Q

What are the causes of a secondary headache (i.e. underlying pathology is causing the headache)?

A
  • RICP
  • Infections
  • Temporal arteritis
  • Intracerebral haemorrhage
  • Low pressure headache
  • Post-traumatic
  • Referred from neck
  • Acute glaucoma
  • Malignant HTN
  • IIH
  • Local pathology e.g. dental, sinusitis
33
Q

RICP

A

Headache on waking, worse cough/strain, vomiting, visual obscurations, papilloedema. E.g. SOL, venous sinus thrombosis, hydrocephalus

34
Q

Idiopathic intracranial hypertension

A

typical in younger overweight women.

Transient visual obscurations, CN VI palsy, papilloedema. Normal imaging but exclude other causes.

Usually self-limiting but chronic papilloedema damages optic nerve so monitor, may do repeated LP/acetazolamide + thiazides, adv weight loss, sometimes need VP shunt/optic nerve sheath fenestration to help vision

35
Q

Low pressure headache

A

CSF leak. E.g. post-LP

postural (worse on sitting/standing, relief when flat)

M – autologous blood injections into epidural space to seal leak, sometimes surgery, sometimes IV caffeine infusion + bed rest

36
Q

Post-traumatic headache?

A

usually improves after a few weeks

obv if acute ensure not EDH/SDH

consider SDH + low-pressure headache

37
Q

Red flag symptoms for headache

A

thunderclap, fever, meningism, non-blanching rash, RICP (morning headache, worse coughing, papilloedema), new neuro sx/cognitive dysfunction, personality change, reduced GCS, recent head injury, new onset in elderly, significant change in pattern of a daily headache (SOL), h/o malignancy/immunosuppression, pregnancy (PET)