Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

FFM-I Mini 2 > Mini 2 > Flashcards

Mini 2 Flashcards

1
Q

Toxin: Benzodiazapines
Antidote:

A

Flumazenil

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Selective antagonist of 𝛼2

A

Yohimbine (NOT USED!!!)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

All blood vessels
Receptor type:
Receptor response when active:

A

Receptor type: β2

Receptor response when active: Vasodilation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Toxin: Aspirin/ salicylate toxicity
Toxic Metabolite:
Antidote:

A

Toxic Metabolite: Uncoupling of OxPhos in mitochondria

Antidote: Gut Decontamination, gastric lavage; activated charcoal; IV fluids; IV BiCarb

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Nicotinic receptors

A

Nn
Nm

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Selective antagonist of β1

A

Atenolol
Metroprol

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Toxin: CO
Antidote:

A

100% O2

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Path from Tyrosine to NE

A

Tyrosine - DOPA via Tyrosine Hydroxylase (RATE LIMITING STEP!)
DOPA to Dopamine
Dopamine to NE
NE to Epi

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Heart - SA Node
Receptor type:
Receptor response when active:

A

Receptor type: β1

Receptor response when active: Increased HR

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Toxin: Irritant gases (Chlorine, ammonia, sulfur, NO)
Antidote:

A

Humidified O2
Bronchodilators

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Toxin: Lead
Chealator:

A

Edetate Calcium Disodium Ethylenediamintetraacetic acid (EDTA)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Affects on Adrenergic Receptors:
Inhibits Uptake 1 at nerve terminal

A

Cocaine
Imiparamine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Selective agonist of 𝛼2

A

Clonidine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Site: Arterioles
Predominant Tone:

A

Sympathetic - cholinergic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Coronary Vasculature
Receptor type:
Receptor response when active:

A

Receptor type: D1

Receptor response when active: Vasodilation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Skeletal Muscles
Receptor type:
Receptor response when active:

A

Receptor type: β2

Receptor response when active: Increase glycogenolysis (contractility)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Kidney
Receptor type:
Receptor response when active:

A

Receptor type: β1

Receptor response when active: Increased Renin release

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

Male Sex Organs
Receptor type:
Receptor response when active:

A

Receptor type: 𝛼1

Receptor response when active: Ejaculation of vas deferens

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Radial muscle of eye
Receptor type:
Receptor response when active:

A

Receptor type: 𝛼1

Receptor response when active: Contraction

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

Toxin: Copper
Chealator:

A

Penicillamine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

Heart AV Node
Receptor type:
Receptor response when active:

A

Receptor type: β1

Receptor response when active: Increased conduction

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

Toxin: CO
Antidote:

A

Oxygen

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

Toxin: Mushroom poisoning (muscarinic excessive symptoms)
Antidote:

A

Atrophine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

Affects on Presynaptic Parasympathetic Cholinergic Transmission:
Inhibit release of ACh

A

Botulinum Toxin (anticholinergic)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
Q

Antagonists of Nm receptors

A

Hexamethonium
Mecamylamine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
26
Q

Toxin: Delirium due to anticholinergic agents
Antidote:

A

Physostigmine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
27
Q

Selective agonist of β2

A

Albuterol
Terbutaline

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
28
Q

Toxin: Oxidizing Agents
Antidote:

A

Methylene Blue

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
29
Q

Affects on Presynaptic Parasympathetic Cholinergic Transmission:
Inhibit Vesicular Storage of ACh

A

Vesamicol (anticholinergic)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
30
Q

Toxin: Cyanide
Antidote:

A

Hydroxycobalamin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
31
Q

Uterus
Receptor type:
Receptor response when active:

A

Receptor type: β2

Receptor response when active: Relaxation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
32
Q

Bronchioles
Receptor type:
Receptor response when active:

A

Receptor type: β2

Receptor response when active: Dilation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
33
Q

Affects on Adrenergic Receptors:
Inhibits NE placement within vesicles

A

Amphetamines
Tyramine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
34
Q

Enzymes involved in termination of ACh

A

Acetylcholinesterase
Butyrylcholinesterase

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
35
Q

Toxin: B-blockers
Antidote:

A

Glucagon

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
36
Q

Site: Sweat Glands
Predominant Tone:

A

Sympathetic - cholinergic

37
Q

Toxin: Theophylline, caffeine, metaproterenol
Antidote:

A

Esmolol

38
Q

Prejunctional nerve terminal
Receptor type:
Receptor response when active:

A

Receptor type: 𝛼2

Receptor response when active: Decreased NR release and NE synthesis

39
Q

Selective agonist of β1

A

Dobutamine

40
Q

Site: Veins
Predominant Tone:

A

Sympathetic - cholinergic

41
Q

Selective agonist of 𝛼1

A

Phenylephrine

42
Q

Toxin: Cyanide
Antidote:

A

Nitrites - induce methemoglobinemia
Thiosulfate - converts cyanide to Thiocyanate

43
Q

Toxin: Digoxin; cardiac glycosides
Antidote:

A

Digoxin Abs

44
Q

Toxin: Iron
Chealator:

A

Deferoxamine
Deferasirox

45
Q

Toxin: Iron salts
Antidote:

A

Deferoxamine

46
Q

Heart - AV muscles
Receptor type:
Receptor response when active:

A

Receptor type: β1

Receptor response when active: Increased contraction

47
Q

Affects on Presynaptic Parasympathetic Cholinergic Transmission:
Promote release of ACh

A

Latrotoxin (spider venom) (cholinergic)

48
Q

Rate Limiting Enzyme of ACh synthesis

A

Choline Acetyltransferase

49
Q

Heteroreceptors

A

Resides on nerve cell
Sensitive to NT’s/Hormones released by other cells

50
Q

Antagonist of Nn receptors

A

Tubocurarine
Atracurium

51
Q

Affects on Presynaptic Parasympathetic Cholinergic Transmission:
Anticholinesterases

A

Neostigmine (favors cholingeric receptors)

52
Q

Toxin: Anticholinesterase Intoxication
Antidote:

A

Atrophine

53
Q

Trigone/Sphincter of Urethra
Receptor type:
Receptor response when active:

A

Receptor type: 𝛼1

Receptor response when active: Contraction (urinary retention)

54
Q

Selective antagonist of β2

A

Butoxamine (NOT USED!!!)

55
Q

Affects on Presynaptic Parasympathetic Cholinergic Transmission:
Inhibit Choline Carrier

A

Hemicholinium (anticholinergic)

56
Q

Enzymes used to metabolize NE

A

Monoamine oxidase
Catechol-O-methyl transferase

57
Q

Liver
Receptor type:
Receptor response when active:

A

Receptor type: 𝛼1

Receptor response when active: Increased glycogenolysis

58
Q

NE synthesized from

A

Tyrosine

59
Q

Toxin: Fluoride/Ca2+ channel blockers
Antidote:

A

Calcium

60
Q

Kidney
Receptor type:
Receptor response when active:

A

Receptor type: 𝛼1

Receptor response when active: Decreased Renin secretion

61
Q

Toxin: Mercury
Chealator:

A

Succimer (dimercaptosuccinic acid)

62
Q

Toxin: Organophosphates; Cholinesterase inhibitors
Antidote:

A

Pralidoxime (2-PAM)

63
Q

Site: Iris
Predominant Tone:

A

Parasympathetic - cholingergic

64
Q

Arterioles of skin/viscera
Receptor type:
Receptor response when active:

A

Receptor type: 𝛼1

Receptor response when active: Contraction = increase BP

65
Q

Veins
Receptor type:
Receptor response when active:

A

Receptor type: 𝛼1

Receptor response when active: Contraction = increase preload

66
Q

Selective antagonist of 𝛼1

A

Prazosin

67
Q

Platelets
Receptor type:
Receptor response when active:

A

Receptor type: 𝛼2

Receptor response when active: Platelet aggregation

68
Q

Site: Salivary Glands
Predominant Tone:

A

Parasympathetic - cholingergic

69
Q

Affects on Adrenergic Receptors:
Inhibits release of NE from vesicle

A

Bretylium
Guanethidine

70
Q

Toxin: Narcotic drugs
Antidote:

A

Naloxone

71
Q

Toxin: Hydrogen sulfide
Antidote:

A

No specific treatment
Recommend Nitrites

72
Q

Renal vasculature
Receptor type:
Receptor response when active:

A

Receptor type: D1

Receptor response when active: Vasodilation

73
Q

Pancreas
Receptor type:
Receptor response when active:

A

Receptor type: 𝛼2

Receptor response when active: Decrease Insulin secretion

74
Q

Heart - His/Purkinje fibers
Receptor type:
Receptor response when active:

A

Receptor type: β1

Receptor response when active: Increased automaticity/Conduction

75
Q

Toxin: Acetaminophen
Toxic Metabolite:
Antidote:

A

Toxic Metabolite: N-acetyl-p-benzoquinone imine NAPQI

Antidote: n-acetylcysteine (NAC)

76
Q

Site: Ciliary Muscle of eye
Predominant Tone:

A

Parasympathetic - cholingergic

77
Q

Autoreceptors

A

Resides on nerve cell
Sensitive to NT/hormones released BY neuron where autoreceptor sits

78
Q

Toxin: Lead
Chealator:

A

Succimer (Dimercaptosuccinic acid)

79
Q

Site: GIT
Predominant Tone:

A

Parasympathetic - cholingergic

80
Q

Affects on Adrenergic Receptors:
Interfere with synthesis of NE

A

Metyrosine

81
Q

Site: Heart
Predominant Tone:

A

Parasympathetic - cholingergic

82
Q

Toxin: Mentanol/ethylene glycol
Antidote:

A

Ethanol
Fomepizole

83
Q

Affects on Adrenergic Receptors:
Inhibits Storage/Uptake of NE

A

Resperine

84
Q

Site: Genital Tract
Predominant Tone:

A

Sympathetic AND Parasympathetic

85
Q

Liver
Receptor type:
Receptor response when active:

A

Receptor type: β2

Receptor response when active: Increase glycogenolysis

86
Q

Toxin: Tricyclic antidepressants
Antidote:

A

Sodium Bicarbonate

87
Q

Site: Bladder
Predominant Tone:

A

Parasympathetic - cholingergic

88
Q

Mesenteric vasculature
Receptor type:
Receptor response when active:

A

Receptor type: D1

Receptor response when active: Vasodilation

89
Q

Pancreas
Receptor type:
Receptor response when active:

A

Receptor type: β2

Receptor response when active: Increase Insulin Secretion

FFM-I Mini 2 (7 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions