minerals Flashcards
most abundant mineral in the body? in the form of?
calcium, in the form of hydroxyapetite in bones
what transports copper in blood?
ceruloplasmin
what are metallochaperones?
bind Cu within the target cell and usher is to the appropriate compartment. CCS for SOD, Cox17 for cytochrome c oxidase
menkes disease and wilsons disease are both due to defects in-
ATP7B
what is the main excretion form of zinc?
by the pancreas in the form of pancreatic enzymes
acrodermitis enteropathica
AR disorder affecting Zn absorption
selenium is necessary for the synthesis of what class of enzyme?
glutathione peroxidases
what is unique about glutathione peroxidase IV?
acts directly on per oxidized portions of phospholipids
what part of thyroid hormone synthesis depends on Se?
deiodinases
what is the main role of chromium?
enhances the effectiveness of insulin
how does Zn deficiency impair folate?
decreased Zn = impaired conjugate = decreased folate absorption
how does Cu deficiency cause anemia?
Cu deficiency impairs iron absorption, leading to microcytic anemia