Mikey's Pharmacy Party Flashcards
Drug Idiosyncrasy
Unusual reactions that does not occur in majority of patients.
6 rights
- Patient
- Drug
- Route
- Dose
- Time
- Documentation
Receptor
Macromolecule that binds to the substance(drug)
5 bronchodilator classes
- Beta 2 agonist
- Muscarinic antagonist
- Leukotriene antagonist
- Mast cell stabilizer
- Corticosteroid
Inhaled corticosteroids treats…
Long term asthma
Contraindicated analgesics for sulfa allergies?
Celecoxib
CNS stimulant use
ADHD
Narcolepsy
Route for sensitivity testing?
ID
Parenteral routes?
IM
IV
SC
ID
Who can prescribe medication?
Accredited providers
Cumulative drug affect:
Drug has not fully metabolized before next dose.
Synergism:
Occurs when drugs produce an effect greater than the sum of separate actions
Pharmacodynamics:
Action
Effect
Naloxone antagonist to:
Morphine
Thyroid hormone action:
Increases metabolic rate of tissue
Progesterone:
Natural female hormone
Progestin
Synthetic female hormone
Proton pump instructions
30-60min before a meal
Bi-daily: breakfast and dinner
Agonist
Binds with receptors to produce therapeutic response
Oral anti-diabetic use:
DM type 2
Pharmaceutics phase:
Dissolution of a drug
Sedative and Hypnotic aka…
Barbiturates
Sedative and Hypertonic treat:
Seizures
Alcohol withdraw
Anti-convulsion
3 contraindications a for MAOI?
CHF
14 days of TCA
Setraline use with MAOI is fatal
How long do antidepressants take to work?
4-6 weeks
Dry cough is a side effect of?
ACE inhibitors
When do you use insulin?
DM type 1
Severe type 2
4 factors effecting insulin dosing?
- Pt eats too little
- Dose incorrectly measured
- Drastic increase in PT
- Infection
What reaction occurs when the combined effect of 2 drugs is equal?
Addictive reaction
What occurs when a drug produces an effect that is greater than the sum of their separate actions
Synergism
1+1=3
6 Factors influencing drug response
Age Weight Gender Disease Route IV( most rapid) Drug use/ pregnancy
What are 3 ORAL routes?
Nasogastric tube
Buccal
Sublingual
What are the 4 PARENTERAL drug administration?
SC ( between skin and muscle )
IM
IV
ID ( typically used for sensitivity test )
Drugs that can be applied to the skin or mucus membrane?
Topical
Transdermal ( SYSTEMIC EFFECT )
Inhalation ( LOCAL EFFECT )
What are the actions of barbiturates?
Anticonvulsant Depressed sensory cortex Decreased motor activity Drowsiness Sedation Hypnosis (NO ALCOHOL USE)
What are the 2 anti-anxiety drug classes?
Benzodiazepines ( short term use )
Non Benzodiazepines
What are some example’s of benzodiazepines?
Alprazolam
Diazepam
Lorazepam
Pam Pam Pam
What are the 5 classes of antidepressants?
(TCA)-Tricyclic antidepressants
(MAOI)-Monoamine Oxidase Inhibitors
(SSRI)-Selective Serotonin Reuptake Inhibitors
(SANRIs)-Serotonin-norepinephrine reuptake inhibitor
Dopamine/Norepinephrine-Reuptake Inhibitors
What is the action of antipsychotics?
Block dopamine receptors in the brain
What is the use of an antipsychotic?
Treat acute and chronic psychosis
What are the contraindications of antipsychotics?
Servers depression
Hypotension
What is the use of anticonvulsants?
Used to decrease the severity of seizures
What drug do you not give patients with epilepsy?
Welbutrol
Drug tolerance:
Decrease response to a drug, increase dose for therapeutic effect.
Pounds to KG?
Divide by 2.2
Contraindications for ketamine?
Cardiac issues
Ketamine has what kind of effect?
Catalyptic
Pharmacogenetic reactions
Inherited trait that causes abnormal metabolism.
What are the 5 anti-acid uses?
Heartburn GERD Sour stomach Indigestion Peptic ulcer
H2 antagonist action:
Reduce secretion of gastric acid
What are 2 examples of anti-anxiety meds?
Diazepam
Lorazepam
Short term due to dependence
What is the action of ant-emetics and anti-nausea meds?
Block 5-HT3 receptor sights
What is the pregnancy code for antiemetic and anti-nausea meds
X do not use
Best medication for antiemetic and anti-nausea
Odanestron
Formerly Phenogren
4 analgesic classes:
Salicylate
Non Salicylate
NSAID
Urinary
Antipyretic use:
Reduce body temp
Antianginal aka:
Nitrates
Contraindications for antianginal?
Hypotension
Avoid ace inhibitors in what population?
AA
Thyroid hormone examples:
Levothyroxine
Aka Synthroid
Beta blocker treat what chronic condition?
Angina
Beta blocker action:
Decreases heart rate
Reduces excitability
4 antihypertensive drug classes:
Ace/ Arb
Diuretics
Calcium channel blockers
Beta blockers
Stage 1 HTN:
Systolic=130-139
Diastolic=80-89
Stage 2 hypertension:
140/90
Where is the cough center?
Medulla
What is the most common expectorant?
Guaifenesin
Drug physiology:
Pancreas
Circulates through blood
Metabolized in the liver
Filtered through kidneys
What drugs are contraindicated in patients with G6PD?
Aspirin
Chloroquine
Sulfamides
6 factors of bioavailability
Route Liver metabolism GI mucosa Good/drugs Solubility Drug form
SIGNA definition
Patient instructions. No numbers and no abbreviations
Pharmacodynamics
Drug action and effects
Hemorrhoid agents aka
Topical corticosteroid
Hemorrhoid agent adverse effect
Tissue atrophy
Liver disease effect on dose
Lower dose; med not well metabolized by liver
MANMED Pharmacy chapter
21
DOD prescription form
DD1289
Fat soluble vs water soluble
Fat soluble is faster and lasts longer
Bioavailability
% of drug administered in that reaches circulation
Bioavailability
% of drug administered that reaches circulation
Pinotcytosis
cell drink
active absorption
requires energy/ ATP
passive absorption
diffuses high to low
Beta 2 Agonist contraindications
Cardiac Arrhythmia
Beta 2 Agonist action
Blocks Beta Blocker