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Clinical Chemistry 1 > Midterms > Flashcards

Midterms Flashcards

1
Q

speed of analytical system

A

throughput

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2
Q

reagents and samples are combined to

A

yield a spec final conc

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3
Q

incubation is controlled by

A

analyzer

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4
Q

measurement in the cuvette where the rxn has taken place

A

situ monitoring

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5
Q

restricted to certain math fxns

A

digital computation

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6
Q

time analyzer is not in use

A

maintenance time

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7
Q

system

A

q assurance

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11
Q

converter changes the _______ into digital

A

voltage or current signal

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12
Q

electrical signal from SENSOR or PHOTOELECTRICAL CELL

A

analog

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13
Q

list of analytes or test for patient testing

A

test menu

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14
Q

tool

A

QC

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15
Q

analog computation compares it with reference signal as for the

A

blank soln

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16
Q

waiting period mixture allowed time to react

A

incubation

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17
Q

readout with

A 
tv monitor (cathode ray tube)
light emitting diodes
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20
Q

the ability of a method to determine the exact value of the substance of interest in the sample

A

accuracy

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21
Q

precision

A

standardization

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22
Q

number of test performed on instrument

A

test repertoire

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23
Q

minimum time to obtain result after initial sampling

A

dwell time

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24
Q

labor maintenance, capital, reagent, qc

A

cost

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25
Q

100% pure

A

standard sol

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26
Q

for precision

A

control sol

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27
Q

overall management plan to guarantee integrity of data

A

quality assurance

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28
Q

max tests in an hour

A

throughput

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30
Q

instrument performs other tasks while processing the test

A

walk away capability

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31
Q

range which results can be reported without manipulating the sample

A

linearity

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34
Q

used as basis of reference for the calc of the value of unknown

A

standard sol

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35
Q

highest and lowest calibration for an instrument

A

linear range

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37
Q

time analyzer is unavailable because of periodic maintenance or troubleshoot

A

downtime

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38
Q

reuse of cuvette

A

carry over

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39
Q

percentile exp of the mean

A

cv

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40
Q

monitoring via

A

optical
thermal
electrical

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41
Q

degree by which significant deviations can be detected

A

sensitivity

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42
Q

able to measure minute conc of the analyte

A

analytical sensitivity

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43
Q

the test must always give a (+) result in the presence of a disease

A

diagnostic sensitivity

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45
Q

the test must always give a negative result in the absence of disease

A

diagnostic specificity

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46
Q

the ability of a method to give repeated results on the same sample that agrees with one another

A

precision and reproducibility

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48
Q

composed of SEVERAL known constituents which can be run simultaneously with the test to check ACCURACY

A

control sol

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49
Q

serves as reference for unknown

A

standard sol

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50
Q

error due to instrument itself

A

instrumental

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51
Q

composed of one known constituent

A

standard sol

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52
Q

set the reading to zero

A

blank

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55
Q

the degree by which a method is easily repeated

A

practicality

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56
Q

control val on one side 6 days

A

shift

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57
Q

commercially prepared

values are know but NOT GIVEN

A

unassayed

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58
Q

cusum graph

A

cumulative sum

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59
Q

sol without the specimen but with reagent

A

blank

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60
Q

lowest value detected without giving a false positive result

A

sensitivity

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61
Q

known char
known value
known conc

A

standard sol

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62
Q

changes in the conc of standards

A

trend

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64
Q

source of non commercially prepared qc reagents

A

left over sera (pooled sera)

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67
Q

providing positive sample identification

A

bar code

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68
Q

ration of sd over mean

A

cv

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69
Q

leads to outliers

A

gross or blunders

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70
Q

fundamental basis of any statistical analysis

A

variation

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71
Q

proficiency testing

A

external quality control prog

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72
Q

deteriorating of standard

A

shift

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73
Q

pooled serum (1 yr)

A

control

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74
Q

only performs req. test

A

selective

76
Q

2 mean chart at right angles

A

youden plot

77
Q

correction of re

A

use of high grade equip

careful use of the equip

78
Q

derived from human blood

A

control

79
Q

2 or more outliers 20 days

A

out of control

80
Q

control chart

increase or decrease 6 days

A

trend

81
Q

types of determinate systematic

A

personal
methodic
instrumental

82
Q

manuf from diff companies

lyophilized or non lyophilized

A

commercially prepared

83
Q

practical conciderations jn qc prog

A 
specimen collection and handling
reagent and equipment
method and procedure
standard and control
qualified personnel
84
Q

reagent stability before use

A

shelf life

85
Q

commercially prepared

values are known and GIVEN

A

assayed

86
Q

correction of methodic err

A

proper method dev or procedural changes

88
Q

carried deoxygenated blood

A

vein

89
Q

measure of relative magnitude of variability

A

cv

90
Q

error affects precision of result

A

random

91
Q

loss of blood from a vessel

A

hematoma

92
Q

measures significant differences bet groups of data

A

variance

93
Q

error that affects the accuracy

A

systematic

94
Q

most commonly used chart

A

shewhart levey jennings

95
Q

due to carelessness, prejudice and color acuity probs

A

personal

96
Q

taking blood from an artery (radial)

A

arterial blood gas

97
Q

twin
two mean
two way average

A

youden plot

99
Q

establish reference values in the lab

A

internal qc prog

100
Q

measure the analyte requested only

A

specificity

101
Q

correction of instrumental err

A

calibration

proper instrument maintenance

102
Q

group measurements in the same sample in a cluster around the mean bell shaped

A

gaussian curve

103
Q

requires stat tech to be rejected

A

gross or blunders

104
Q

PROCEDURE needle in vein for venous blood

A

veni

105
Q

with albumin globulin and fibrinogen

A

plasma

106
Q

summation of data divided by total num

A

arithmetic val
mean
average

108
Q

series of analytical measurements to assess quality of analytical data

A

QC

109
Q

Collection of sample

A

bar coded labels

110
Q

aka dot chart

A

shewhart levey jennings

111
Q

liqud portion of clotted blood

A

serum

112
Q

2 signal’s log as the

A

final result for unknown sample

113
Q

improper calibration in instruments

A

shift

114
Q

values far from main set of val

A

outliers

115
Q

ACT of entering a vein to obtain venous blood

A

phlebotomy

116
Q

contain albumin and globulin only

A

serum

117
Q

main cause of outliers

A

random or systematic

118
Q

1 outlier 20 days

A

in control

120
Q

carry oxygenated blood

A

artery

121
Q

connects small arteries and veins

A

capillary

123
Q

lipemia disturbs

A 
amylase
bilirubin
bsb test
protein
sgot
sgpt
125
Q

cause of hemoconc

A

lack of fluid in blood

too tight or prolonged torniquet

126
Q

installs blood sample from 0.1-0.9

A

micromethod

127
Q

cavity or channel the tubular org

A

lumen

128
Q

blood clot in a vessel

A

thrombosis

129
Q

prefered specimen in cc

A

serum

130
Q

24 hr sample
random
timed

A

urine

131
Q

nothing per orem
nothing by mouth
8 to 14 hours

A

fasting

132
Q

collected anytime

A

random

133
Q

collected in 24 hours

A

24 hour

134
Q

collected after meal

A

post prandial

135
Q

installs blood sample from 0.01-0.09

A

ultramicromethod

136
Q

installs blood sample 1ml and above

A

macromethod

137
Q

installs blood sample from 0.001-0.009

A

nanoliter method

138
Q

mixture of blood coming from the arterioles, venules and capilaries

A

capillary puncture

139
Q

site for capillary puncture

A

palms
big toe
heel
earlobes

140
Q

lipemia composition changes

A 
bacterial changes
blood gas changes
extravascular interchange
change in lipid conc
change in phosphates
141
Q

samples 2 hours after eating fatty meal

A

lipemic

142
Q

statement of the extent of var in ANY series of measurement

A

sd

145
Q

plasma and formed elements

A

whole blood

146
Q

analog to digital converter to process signals

A

digital

147
Q

capillary puncture is for

A

pediatric infant
geriatrics
extreme obesity
burns

148
Q

4 charts

A

shewhart-levey jennings
gaussian curve
cumulative sum
youden plot

150
Q

closeness of test value to true value

A

accuracy

152
Q

no anticoagulant

A

serum

155
Q

a rejection or warning rule used to identify/indicate if the analytical process is out of control

A

westgard control rules

157
Q

with anticoagulant

A

plasma

158
Q

deteriorating reagent

A

trend

159
Q

due to unpredictable cause

origin not determined

A

random

160
Q

magnitude can be determined, tangiole

A

systematic

d or r

161
Q

errors in qc

A

variation

163
Q

due to the method which cannot be eliminated unless a change is made with it

A

methodic

165
Q

plotted w diff from mean of individual values w the middle value being ZERO

A

cusum

166
Q

limition of observation

A

limited re

167
Q

able to measure only one unknown substance

A

analytical specificity

170
Q

diameter of needle

larger no = smaller

A

gauge

171
Q

types of random error

A

inherent

limited

176
Q

correction of personal err

A

proper training and xp

178
Q

measure of the distribution range of values around the mean val or average

A

sd

182
Q

kinds of qc reagents

A

commercially prepared

noncommercially prepared

191
Q

types of error

A

random or indeterminate
determinate or residual or systematic
gross or blunders

194
Q

for accuracy

A

standard sol

blank

202
Q

number of test RESULT generated at a given time

A

workload

223
Q

mixing of reagents can be done by

A

stirring
agitation
other device

Clinical Chemistry 1 (1 decks)

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