Midterm study Flashcards

1
Q

A shipment of packed red blood cells and platelets arrived together in the same box stored at 1-6C. What should be done?

a. Place all units in 1-6C refrigerator.
b. Reject the entire shipment.
c. Accept the red cells, discard the platelets.
d. Accept the platelets, discard the red cells.

A

c. Accept the red cells, discard the platelets.

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2
Q

A unit of whole blood is collected at 10am and stored at 20-24C. What is the last hour cryoprecipitateconcentrates may be made from this unit?

a. 4pm
b. 6pm
c. 7pm
d. 8pm

A

b. 6pm

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3
Q

Which of the following is true regarding apheresis platelets?

A. Minimum platelet count in a unit must be 3.0 x 10^11 PH<6.0
B. Minimum platelet count in a unit must be 3.0 x 10^10 PH<6.2
C. Minimum platelet count in a unit must be 3.0 x 10^11 PH>6.2
D. Minimum platelet count in a unit must be 5.5 x 10^10 PH>6.0

A

C. Minimum platelet count in a unit must be 3.0 x 10^11 PH>6.2

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4
Q

All of the following statements are true except:

A. Centrifugation is an acceptable method for preparing LRBCs
B. Graft vs Host may be prevented by visual inspection of the unit
C. Circulatory overload may be caused by transfusing plasma improperly
D. Leukodepletion filters may prevent febrile transfusion reactions.

A

B. Graft vs Host may be prevented by visual inspection of the unit

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5
Q

All of the following statements are true about FFP except:

A. FFP must be prepared within 24 hours of collection
B. After thawing, FFP must be transfused or relabeled within 24 hours
C. Storage temp for FFP is <-18C
D. After thaw FFP must be stored at 1-6C until transfusion

A

A. FFP must be prepared within 24 hours of collection

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6
Q

What is the expiration date of a previously frozen deglycerolized RBC unit?

A. 1 year
B. 42 days
C. 21 days
D. 24 hours

A

D. 24 hours

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7
Q

What should be done if a noticeable clot is observed in a unit?

A. Issue the unit, the blood will be filtered
B. Issue the unit, note the clot on the issue form
C. Filter the unit in the blood bank before issue
D. Do not issue the unit

A

D. Do not issue the unit

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8
Q

Cyroprecipitate can be used to treat all of the following except:

A. Von willebrand’s disease
B. Hypofibrinogenemia
C. ITP
D. Factor XIII deficiency

A

C. ITP

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9
Q

What types of products should be given to a patient who has IgA antibodies?

A. Whole blood
B. PRBCs
C. Washed cells
D. Plasma

A

C. Washed cells

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10
Q

FP24 can be transfused without regard for which of the following?

A. ABO
B. Rh
C. Antibody in the product
D. All of the above

A

B. Rh

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11
Q

How should plateletpheresis be stored in the blood bank?

A. Room temperature, stacked upright
B. Refrigerator temperature, stacked upright
C. Refrigerator temperature, slightly agitated
D. Room temperature, slightly agitated

A

D. Room temperature, slightly agitated

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12
Q

Which component has the longest expiration date?

A. Platelets
B. Frozen cryoprecipitate
C. FP24
D. Frozen red cells

A

D. Frozen red cells

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13
Q

Which product has the shortest expiration date?

A. Thawed cryoprecipitate
B. Thawed FFP
C. Thawed FP24
D. Platelets

A

A. Thawed cryoprecipitate (4-6 hrs)

Thawed FFP=5 days
Thawed FP24=24 hrs
Platelets=5 days

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14
Q

Situation: A cancer patient recently developed a severe infection. The patient’s hemoglobin is 8g/dL owing to chemotherapy with a drug known to cause bone marrow suppression. Which blood products are indicated?

A. Liquid plasma & Cryoprecipitate
B. Crossmatched platelets & Washed RBCs
C. Factor IX & FFP
D. Irradiated RBCs and Granulocytes

A

D. Irradiated RBCs and Granulocytes

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15
Q

Which coagulation factors are diminished in products labeled “thawed plasma”?

A. XIII & VWF
B. V & VIII
C. Fibrinogen & VIII
D. VII & Fibrinogen

A

B. V & VIII

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16
Q

What cells are HLA antigens typically on?

A. Red cells
B. White cells
C. Platelets
D. 2 of these

A

D. 2 of these

HLA on all nucleated cells, granulocytes, lymphs and platelets

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17
Q

What clinical applications can HLA typing be used for?

A. Paternity testing
B. Breast Cancer risk
C. Bone marrow matching
D. All of these

A

D. All of these

18
Q

The HLA genes are on which chromosome?

A. 2
B. 4
C. 6
D. 8

A

C. 6

19
Q

What is the test of choice for HLA antigen testing?

A. Agglutination
B. Molecular
C. Cytotoxicity
D. ELISA

A

C. Cytotoxicity

20
Q

Of the following diseases, which has the strongest correlation with HLA type?

A. Ankylising spondylitis
B. Transfusion Reaction
C. Cancer
D. Sickle Cell Anemia

A

A. Ankylising spondylitis

21
Q

Which of the following is acceptable as a donor?

A. 29 yo who received flu vacc last month.
B. 21 yo who got nose pierced last week in Georgia.
C. 30 yo who used to live in Zambia and returned last year.
D. 54 yo tested pos for HepC last year but no active symptoms

A

A. 29 yo who received flu vacc last month.

22
Q

Which vaccine has the longest deferral period?

A. Hep B Ig
B. Rubella
C. Influenza
D. Yellow fever

A

A. Hep B Ig

23
Q

Which of the following donors are qualified to donate on September 10?

A. 40 yo who donated RBCs on July 23
B. 28 yo who donated platelets on Aug 24
C. 52 yo who made an autologous donation 2 days ago
D. 23 yo who donated blood for her aunt on Aug 14

A

B. 28 yo who donated platelets on Aug 24

24
Q

Which of the following will cause a potential platelet donor to be temporarily deferred?

A. Platelet count 75 x 10^9
B. Plasma loss of 400 mL from plasmapheresis 1 week ago
C. Plateletpheresis performed 4 days ago
D. Aspirin ingested 7 days ago

A

A. Platelet count 75 x 10^9

25
Q

Which donor would be acceptable for whole blood donation?

A. Former drug addict who has been clean for2 months
B. Triathlete with a pulse of 45 beats/min
C. A man who is currently in remission for multiple myeloma
D. A woman treated for syphilis 8 months ago

A

B. Triathlete with a pulse of 45 beats/min

26
Q

Which physical exam result is cause for rejecting a whole blood donor?

A. Weight 105 lbs
B. Pulse 75 beats/min
C. Temperature of 99.3F
D. Diastolic blood pressure of 110mmHg

A

A. Weight 105 lbs
and
D. Diastolic blood pressure of 110mmHg

27
Q

Which medication does not defer the potential platelet donor?

A. Plavix
B. Ortho tricyclen
C. Accutane
D. Aspirin

A

B. Ortho tricyclen
just turns plasma green

28
Q

Which of the following does NOT permanently disqualify the donor?

A. Treated for Chagas 3 years ago
B. Receipt of growth hormone 30 years ago
C. Accidental needle stick 1 year ago
D. Need Coumadin daily

A

C. Accidental needle stick 1 year ago

29
Q

Which patient is the best candidate for autologous donation?

A. 45 yo with elective surgery scheduled in 2 weeks; he has anti-Kpb
B. 23 yo leukemia patient with hgb 10g/dL
C. 12 yo hemophiliac boy
D. 53 yo woman who has severe skin infection

A

A. 45 yo with elective surgery scheduled in 2 weeks; he has anti-Kpb

Autologuous donations should be healthy donors w/ high incidence antibodies/rare blood

30
Q

Which of the following is an acceptable time for whole blood collection?

A. 30
B. 35
C. 22
D. 13

A

D. 13

31
Q

Which of the following donors would be accepted for whole blood donation?

A. 37 yo taking Tegison
B. 17 yo with Hgb 12
C. 24 yo who just received the Hep vaccine for employment in the hospital
D. 49 yo from Congo visiting the US for the first time

A

C. 24 yo who just received the Hep vaccine for employment in the hospital

32
Q

Which test is NOT required for allogenic donation testing?

A. Rh
B. STS
C. Anti-HTLV
D. Anti-CMV

A

D. Anti-CMV

33
Q

Which of the following lists the correct shelf life for the product?

A. Deglycerolized RBCs- 24 hours
B. CPD RBCs – 35 days
C. Platelet concentrate – 7 weeks
D. FFP – 5 years

A

A. Deglycerolized RBCs- 24 hours

34
Q

What is the difference between allogenic donor and autologous donor?

A. There is not a minimum age for autologous donors.
B. Hemoglobin value has a lower threshold for autologous than allogenic
C. The autologous donor unit will not be rejected for viral testing results.
D. All of the above

A

D. All of the above

35
Q

Which virus is tested for in blood donations seasonally?

A. Zika
B. West Nile
C. Chagas disease
D. Flu

A

B. West Nile

36
Q

Which of the following is acceptable as a whole blood donor today?

A. 16yo girl who weighs 95lbs
B. 22yo male who got his nose pierced 2 months ago in Oregon
C. 56yo woman released from prison 8 months ago
D. 32yo MLS who had a Hep B Ig vaccination 28 days ago
E. None of the above

A

E. None of the above

37
Q

Which of the following viruses is NOT detected through NAT?

A. HCV
B. HBV
C. HTLV
D. WNV

A

C. HTLV

38
Q

Which product CANNOT be made from a whole blood donation processed within 24 hours?

A. LRBC
B. Platelets
C. FP24
D. Cryoprecipitate

A

D. Cryoprecipitate
must be manufactured in 8 hours due to decreasing amounts of FV & FVIII

39
Q

Which type of red cell would be given to a patient with known allergic reactions to blood products?

A. DRBC
B. LRBC
C. IRBC
D. Whole blood

A

A. DRBC

40
Q

Which product is stored incorrectly?

A. Thawed FFP in 2-6C refrigerator
B. Platelets on ice
C. Cryoprecipitate at room temperature
D. FP24 in <-18C freezer

A

B. Platelets on ice