Midterm Slide Review

Question 1

What is a high alert drug?

Answer 1

A drug that bears a heightened risk of causing significant patient harm when used in error

Question 2

Examples of high alert drugs

Answer 2

Warfarin, Insulin, Prednisone, Finasteride

Question 3

What is a hazardous drug?

Answer 3

Drugs considered hazardous have one or more of these characteristics: Carcinogenicity, Teratogenicity (birth defects), Genotoxicity (damages DNA), Reproductive toxicity (affects fertility), organ toxicity at low doses, and similar structure to known hazardous drugs

Question 4

What is NIOSH?

Answer 4

National Institute for Occupational Safety and Health

Question 5

3 types of hazardous drugs according to NIOSH

Answer 5

1. Antineoplastic drugs (Eg. chemotherapy), 2. Non-antineoplastic drugs (meeting hazardous drug criteria), 3. Drugs that pose reproductive risks

Question 6

Example of hazardous drugs (not specific but categories)

Answer 6

Chemotherapy agents, antivirals, hormones, some bioengineered drugs, immunosuppresants

Question 7

Specific examples of hazardous drugs

Answer 7

Methotrexate (cytotoxic and teratogenic), Azathioprine (immunosuppressive, cytotoxic), Finasteride (pregnant women should NOT handle), Tacrolimus (immunosuppressant- avoid inhalation or direct skin contact)