Midterm One Flashcards
What is the strict definition of infection in surgical sites/tissue in terms of the amount of bacteria?
(10 to the 5th bacterial organisms per gram of tissue)
What are the four NRC classifications for surgery?
(Clean, clean-contaminated, contaminated, and dirty)
A spay, gastrotomy, or enterotomy would all be defined as what NRC classification of surgery?
(Clean-contaminated)
Describe how a clean-contaminated surgery can transition to a contaminated surgery.
(Contents of the organ you enter in a clean-contaminated surgery spill into a space in the body i.e. intestinal contents during an enterotomy spill into the abdominal cavity)
Performing a surgery on a dog with pyoderma would be considered what NRC classification? (Not that you should do this)
(Dirty)
What two endocrinopathies are shown to increase risk factors for surgical site infections in dogs?
(Hyperadrenocorticism/cushings and hypothyroidism)
(T/F) An animal with diabetes mellitus has an increased risk for surgical site infections.
(F, no studies support this conclusion though diabetes mellitus predisposes to other types of infection)
What are the two most important things you as a practitioner can do to prevent surgical site infections?
(Practice aseptic technique and maintain healthy tissue)
What three areas, often caused by infection, can antibiotics not kill any bacteria in?
(Devitalized tissue, fluid pockets, and biofilms)
What are the six Halsted principles?
(Gentle tissue handling, meticulous control of hemorrhage, appose tissues accurately with minimal tension, preserve blood supply to tissues, eliminate dead space, and strict aseptic technique)
How can you determine the difference between a seroma and an abscess in the most simple way?
(Abscess would be hot and painful upon palpation, seroma would not be)
What is the difference between prophylactic and therapeutic uses of antibiotics in terms of surgical use?
(Prophylactic abx are given during surgery only (they prevent infection), therapeutic abx are given during to after surgery (they treat infection)
For which NRC classification of surgery would you use prophylactic antibiotics?
(All except clean)
For which NRC classification of surgery would you use therapeutic antibiotics?
(Dirty for sure, contaminated debated)
For time-dependent antibiotics and use in surgery, when should you redose?
(Every 2 half-lives for as long as your incision is open)
(T/F) Either diluted iodine or chlorhexidine can be used to surgical prepare for an eye surgery.
(F, only dilute iodine, chlorhexidine is toxic to the eyeball)
How would you go about differentiating between a true and spastic entropion?
(Apply a topical anesthetic to the eye to determine if the response it so pain of the eye, if it is spastic the eyelid should return to a normal position and it will not if it is a true entropion)
What three scenarios is temporary tacking to correct an entropion typically used for?
(Young animals, patients with high anesthetic risk, and spastic entropion)
What are the two closure layers for a lateral canthotomy?
(Tarsoconjunctival layer and the skin layer)
Why can strabismus result after a proptosis case?
(Extraocular muscle damage)
How long should tarsorrhaphy sutures be left in place in proptosis cases?
(4 weeks)
What are the four structures that need to be removed in an enucleation?
(Globe, third eyelid and associated gland, conjunctiva, and eyelid margin with meibomian glands)
Why should you avoid pulling on the globe when performing an enucleation, especially in cats?
(You can damage the optic chiasm and blind the other eye)
When should the third eyelid be removed in an enucleation, before or after the eye is removed?
(Doesn’t matter)
How much of the eyelid margin needs to be removed to ensure that you remove the Miebomian glands?
(5-8mm)
What are the three portions of closure in an enucleation?
(Orbital cone, subcutaneous tissue, and skin)
If an eyelid mass involves less than what fraction of the eyelid margin, you can pursue a wedge or house resection.
(Less than ⅓ of the eyelid margin, this involves the mass and the 1mm of eyelid needed on each side for the resection)
The length of the proliferative phase depends on what characteristic of a wound?
(The size)
The inflammatory/debridement phase of wound healing is typically a couple of days/3-6 days, what two issues can lengthen that time period?
(Infection or necrosis)
(T/F) Skin never regains 100% strength after a wound has healed.
(T)
Collagen decreases/increases (choose) in the inflammatory/debridement phase of wound healing.
(Decreases → break stuff down phase)
What is the predominant cell type in the early inflammation stage of wound healing?
(Neutrophils → kill bacteria, debride necrotic tissue)
What is the predominant cell type in the late inflammation stage of wound healing?
(Macrophages → phagocytosis)
What are the five classical signs of inflammation?
(Heat, redness, swelling, pain, loss of function)
Which phase of wound healing is associated with the most exudative discharge?
(Inflammatory phase)
What is the predominant cell type in the proliferative stage of wound healing?
(Fibroblasts)
What are the three components to granulation tissue on a microscopic level?
(Capillaries, collagen, and fibroblasts)
Does granulation tissue have low/high (choose) tissue oxygen tension?
(High)
Granulation tissue is highly resistant/pervious (choose) to infection.
(Resistant)
How do epithelial cells know when to stop migrating during epithelialization?
(Contact inhibition → when they touch each other, they stop migrating)
What cell type is responsible for contraction of a wound?
(Myofibroblasts → contain actin to help pull things together)
What are the two main reasons that high oxygen tension is important for wound healing?
(Neutrophils needs oxygen to kill bacteria and collagen production requires oxygen)
What are the basic solutions (so nothing added in) that can be chosen for lavaging a wound?
(Tap water, 0.9% saline, any IV fluid)
What are the two antimicrobial additives commonly used for lavaging wounds? Be specific.
(Chlorhexidine and povidone-iodine SOLUTION (not scrub, no bubbles they make fibroblasts angry!), these have not been shown to have a better rate of success in wound care clinically but you do you, can’t tell you how many times I’ve diluted iodine to ‘weak tea’)
What is the ideal pressure to lavage a wound with?
(8 psi → large syringe or fluid bag with pressure system with an 18g needle, holes poked in the top of a saline bottle, lots of options)
What are the two goals of your primary bandage layer during the inflammatory phase of a wound?
(Debridement and reduce bacterial contamination)
What are the two goals of your primary bandage layer during the proliferative phase of a wound?
(To not disrupt new fragile tissue and to hold cells/cytokines in → so you want a non-adherent (does not stick) and occlusive (holds moisture in) bandage)
Why is using a wet-to-dry bandage discouraged?
(Though it is great for debridement, it removes healthy tissue as well (non-selective) and is painful for the patient)
How often does a bandage need to be changed during the inflammatory phase of a wound?
(Once a day)