Midterm Medications Flashcards

1
Q

Indications of Sertraline (Zoloft)

A
MDD 
OCD
Panic disorder 
PTSD
PMDD 
social anxiety disorder
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2
Q

Action of SSRI

A

inhibit uptake of serotonin in the CNS

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3
Q

SSRIs

A

sertaline (zoloft)

fluoxetine (prozac)

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4
Q

common side effects

A
Headache
Nausea
Insomnia/anxiety
Weight gain/loss
Sexual dysfunction
Serotonin syndrome: serious, life threatening
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5
Q

contraindications of SSRIs

A

hypersensitivity
concomitant use of SSRIs with or within 14 days of MAO inhibitors
concomitant use of SSRIs with pimozide

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6
Q

serotonin syndrome

A

Most often a drug drug interaction
Symptoms: diarrhea, restlessness, agitation, hyperreflexia, autonomic instability, myoclonus, seizures, delirium, coma, status epilepticus, cardiovascular collapse
Treatment: Removal of agent, medications to block serotonin receptors
Supportive nursing care

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7
Q

indications of Fluoxetine (Prozac)

A
depression 
depressive episodes associated with bipolar 1 disorder and treatment resistant depression 
OCD 
bulimia nervousa
panic disorder 
PMDD
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8
Q

antipsychotics

A
haloperidol 
clozapine 
risperidone 
quetiapine
olanzapine 
aripiprazole
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9
Q

haloperidol

A

haldol

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10
Q

clozapine

A

clozaril

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11
Q

risperidone

A

risperdal

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12
Q

quetiapine

A

seroquel

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13
Q

olanzapine

A

zyprexa

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14
Q

aripiprazole

A

abilify

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15
Q

haloperidol indications

A

psychotic disorders
tourettes disorder
pediatric behavior problems and hyperactivity

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16
Q

action of haldol

A

blocks postsynaptic dopamine receptors in the hypothalamus, limbic system, and reticular formation

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17
Q

contraindications of haldol

A

hypersentivity

co-administration with other drugs that effect the QT wave

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18
Q

side effects of FGA

A
EPS:  Extra Pyramidal Side Effects
Cogwheeling
Dystonia
Akathesia
Tardive dyskinesia (TD)
Parkinsonianism

Neuroleptic Malignant Syndrome (NMS): potentially life threatening

Orthostatic hypotension

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19
Q

FGA

A

Haldol (Haloperidol)

20
Q

Clozapine (clozaril) indications

A

treatment resistant schizo

recurrent suicidal behavior

21
Q

side effects of clozapine

A

low EPS
risk for agranulocytosis and myocarditis
assess for infection
monitor WBC closely-> weekly 1st 6 months and monthly thereafter for maintenance
slow titration up to 300 mg/QD

22
Q

side effects of SGA

A
weight gain
dyslipidemia
T2DM
Accelerated CVD
Metabolic syndrome
23
Q

metabolic syndrome with SGA

A
WHEN PT HAS 3+ of the following: 
abdominal obesity
hight triglyceride
HTN
low HDL
elevated blood glucose level
24
Q

clozapine contraindications

A
hypersensitivity
myeloproliferative disorders
hx of clozapine induced agranulocytosis 
using other drugs that potentially depress bone marrow function
suppressed CNS
25
Q

indications of quetiapine (seroquel)

A

schizophrenia
acute manic episodes
MDD
OCD

26
Q

quetiapine (seroquel) mechanism of action

A

through combo of dopamine and serotonin receptor antagonism

27
Q

Risperidone (Risperdal) indications

A

bipolar mania
schizophrenia
irritability associated with autistic disorder

28
Q

quetiapine (seroquel) contraindications

A

hypersensitivity
drugs that prolong QT wave
hx of arrhythmias including bradycardia

29
Q

Risperidone (Risperdal) contraindications

A

comatose or severely depressed
hypersensitivity
bradycardia, recent MI, uncompensated HF
hx of prolonged QT or arrhythmias

30
Q

Olanzapine (Zyprexa) indications

A

schizophrenia
bipolar disorder
acute agitation associated with schizo and mania

31
Q

Aripiprazole (Abilify) indications

A

bipolar mania
schizophrenia
irritably associated with autistic disorder
MDD adjunctive tx

32
Q

Aripiprazole (Abilify) contraindications

A

hypersensitivity

lactation

33
Q

FGA antipsychotics

A

haloperidol

34
Q

SGA antipsychotics

A
Clozapine (Clozaril)
Risperidone (Risperdal)
Quetiapine (Seroquel)in
Olanzapine (Zyprexa)
Aripiprazole (Abilify)
35
Q

Benztropine (cogentin) indications

A

parkinsonism

drug induced EPS

36
Q

Amantadine (symmetrel) indications

A

parkinsonism

drug induced EPS

37
Q

Amantadine (symmetrel)

A

increases dopamine at the receptor

38
Q

Benztropine (cogentin)

A

blocks acetylcholine receptors to diminish excess cholinergic effects

39
Q

Stimulants

A

Methylphenidate (Ritalin, Concerta)
Dextroamphetamine/amphetamine (Adderall)
Lisdexamfetamine (Vyvanse)

40
Q

Amphetamine/ dextroamphetamine (adderall) indications

A

ADHD

Narcolepsy

41
Q

Amphetamine/ dextroamphetamine (adderall)
lisdexamfetamine (vyvanse)

contraindications

A

Advanced arteriosclerosis
Symptomatic CVD
Moderate to severe htn
Hyperthyroidism

42
Q

Amphetamine/ dextroamphetamine (adderall)
lisdexamfetamine (vyvanse)

side effects

A
Overstimulation
Restlessness
Dizziness
Insomnia 
Headache
Palpations 
Tachycardia 
Elevated BP 
Tolerance
43
Q

Amphetamine/ dextroamphetamine (adderall) and lisdexamfetamine (vyvanse)

mechanism of action

A

CNS stimulation through release of norepinephrine

44
Q

Methylphenidate (Ritalin) indications

A

ADHD

Narcolepsy

45
Q

Methylphenidate (Ritalin) contraindications

A

Hypersensitivity
Pregnancy/ lactation
Clients with anxiety, tension, or agitation
Hyperthyroidism
Glaucoma
Motor tics, Tourette’s syndrome, or family he

46
Q

Side effects of Methylphenidate (Ritalin)

A
Headache 
Nausea
Rhinitis 
Fever
Anorexia
Insomnia 
Tachycardia, palpations, HTN 
GI pain
47
Q

lisdexamfetamine (vyvanse) indications

A

ADHD