Midterm Medications Flashcards
Indications of Sertraline (Zoloft)
MDD OCD Panic disorder PTSD PMDD social anxiety disorder
Action of SSRI
inhibit uptake of serotonin in the CNS
SSRIs
sertaline (zoloft)
fluoxetine (prozac)
common side effects
Headache Nausea Insomnia/anxiety Weight gain/loss Sexual dysfunction Serotonin syndrome: serious, life threatening
contraindications of SSRIs
hypersensitivity
concomitant use of SSRIs with or within 14 days of MAO inhibitors
concomitant use of SSRIs with pimozide
serotonin syndrome
Most often a drug drug interaction
Symptoms: diarrhea, restlessness, agitation, hyperreflexia, autonomic instability, myoclonus, seizures, delirium, coma, status epilepticus, cardiovascular collapse
Treatment: Removal of agent, medications to block serotonin receptors
Supportive nursing care
indications of Fluoxetine (Prozac)
depression depressive episodes associated with bipolar 1 disorder and treatment resistant depression OCD bulimia nervousa panic disorder PMDD
antipsychotics
haloperidol clozapine risperidone quetiapine olanzapine aripiprazole
haloperidol
haldol
clozapine
clozaril
risperidone
risperdal
quetiapine
seroquel
olanzapine
zyprexa
aripiprazole
abilify
haloperidol indications
psychotic disorders
tourettes disorder
pediatric behavior problems and hyperactivity
action of haldol
blocks postsynaptic dopamine receptors in the hypothalamus, limbic system, and reticular formation
contraindications of haldol
hypersentivity
co-administration with other drugs that effect the QT wave
side effects of FGA
EPS: Extra Pyramidal Side Effects Cogwheeling Dystonia Akathesia Tardive dyskinesia (TD) Parkinsonianism
Neuroleptic Malignant Syndrome (NMS): potentially life threatening
Orthostatic hypotension
FGA
Haldol (Haloperidol)
Clozapine (clozaril) indications
treatment resistant schizo
recurrent suicidal behavior
side effects of clozapine
low EPS
risk for agranulocytosis and myocarditis
assess for infection
monitor WBC closely-> weekly 1st 6 months and monthly thereafter for maintenance
slow titration up to 300 mg/QD
side effects of SGA
weight gain dyslipidemia T2DM Accelerated CVD Metabolic syndrome
metabolic syndrome with SGA
WHEN PT HAS 3+ of the following: abdominal obesity hight triglyceride HTN low HDL elevated blood glucose level
clozapine contraindications
hypersensitivity myeloproliferative disorders hx of clozapine induced agranulocytosis using other drugs that potentially depress bone marrow function suppressed CNS
indications of quetiapine (seroquel)
schizophrenia
acute manic episodes
MDD
OCD
quetiapine (seroquel) mechanism of action
through combo of dopamine and serotonin receptor antagonism
Risperidone (Risperdal) indications
bipolar mania
schizophrenia
irritability associated with autistic disorder
quetiapine (seroquel) contraindications
hypersensitivity
drugs that prolong QT wave
hx of arrhythmias including bradycardia
Risperidone (Risperdal) contraindications
comatose or severely depressed
hypersensitivity
bradycardia, recent MI, uncompensated HF
hx of prolonged QT or arrhythmias
Olanzapine (Zyprexa) indications
schizophrenia
bipolar disorder
acute agitation associated with schizo and mania
Aripiprazole (Abilify) indications
bipolar mania
schizophrenia
irritably associated with autistic disorder
MDD adjunctive tx
Aripiprazole (Abilify) contraindications
hypersensitivity
lactation
FGA antipsychotics
haloperidol
SGA antipsychotics
Clozapine (Clozaril) Risperidone (Risperdal) Quetiapine (Seroquel)in Olanzapine (Zyprexa) Aripiprazole (Abilify)
Benztropine (cogentin) indications
parkinsonism
drug induced EPS
Amantadine (symmetrel) indications
parkinsonism
drug induced EPS
Amantadine (symmetrel)
increases dopamine at the receptor
Benztropine (cogentin)
blocks acetylcholine receptors to diminish excess cholinergic effects
Stimulants
Methylphenidate (Ritalin, Concerta)
Dextroamphetamine/amphetamine (Adderall)
Lisdexamfetamine (Vyvanse)
Amphetamine/ dextroamphetamine (adderall) indications
ADHD
Narcolepsy
Amphetamine/ dextroamphetamine (adderall)
lisdexamfetamine (vyvanse)
contraindications
Advanced arteriosclerosis
Symptomatic CVD
Moderate to severe htn
Hyperthyroidism
Amphetamine/ dextroamphetamine (adderall)
lisdexamfetamine (vyvanse)
side effects
Overstimulation Restlessness Dizziness Insomnia Headache Palpations Tachycardia Elevated BP Tolerance
Amphetamine/ dextroamphetamine (adderall) and lisdexamfetamine (vyvanse)
mechanism of action
CNS stimulation through release of norepinephrine
Methylphenidate (Ritalin) indications
ADHD
Narcolepsy
Methylphenidate (Ritalin) contraindications
Hypersensitivity
Pregnancy/ lactation
Clients with anxiety, tension, or agitation
Hyperthyroidism
Glaucoma
Motor tics, Tourette’s syndrome, or family he
Side effects of Methylphenidate (Ritalin)
Headache Nausea Rhinitis Fever Anorexia Insomnia Tachycardia, palpations, HTN GI pain
lisdexamfetamine (vyvanse) indications
ADHD
