Midterm II -- Ch. 12 - The Cell Cycle Flashcards

1
Q

cell division

A

reproduction of cells

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2
Q

cell cycle

A

the life of a cell from the time it is first formed from a dividing parent cell until its own division into two daughter cells.

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3
Q

genome

A

cell’s genetic information.

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4
Q

chromosomes

A

packages carrying genetic material (DNA molecules);

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5
Q

chromatin

A

complex DNA and proteins that makes up eukaryotic chromosomes.

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6
Q

sister chromatids

A

2 joined copies of a duplicated chromosome.

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7
Q

centromere

A

the region on each sister chromatid where they are most closely attached to each other by proteins that bind to specific DNA sequences.

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8
Q

somatic cells

A

all body cells except the reproductive cells.

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9
Q

gametes

A

sperm and eggs in reproductive cells.

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10
Q

mitosis

A

division of genetic material in the nucleus.

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11
Q

cytokinesis

A

division of the cytoplasm.

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12
Q

mitotic (M) phase

A

phase of cell cycle that include mitosis and cytokinesis.

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13
Q

interphase

A

dividing cell grows and copies its chromosomes in preparation for cell division.

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14
Q

prophase

A

1st stage of mitosis; chromatin condenses into discrete chromosome, mitotic spindle begins to form, nucleolus disappears.

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15
Q

prometaphase

A

2nd stage of mitosis: nuclear envelope fragments and spindle microtubules attach to the kinetochores of the chromosome.

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16
Q

metaphase

A

3rd stage of mitosis: spindle is complete and chromosomes are attached at the metaphase plate.

17
Q

anaphase

A

4th stage in mitosis:chromatids of each chromosome have separated and the daughter chromosomes are moving to the poles of the cell.

18
Q

telophase

A

5th (and final) stage of mitosis: daughter nuclei are forming and cytokinesis has begun.

19
Q

mitotic spindle

A

assemblage of microtubules and associated proteins that is involved in the movement of chromosomes during mitosis.

20
Q

centrosome

A

functions throughout the cell cycle to organize the cell’s microtubules.

21
Q

aster

A

radial array of short microtubules that extends from sac centrosome toward the plasma membrane.

22
Q

kinetochore

A

structure of proteins attached to the centromere that links each sister chromatid to the mitotic spindle.

23
Q

metaphase plate

A

(imaginary) structure located at a plane midway between the two poles of a cell in metaphase on which the centromeres of all the duplicated chromosomes are located

24
Q

cleavage

A

process of cytokinesis, characterized by pinching of the plasma membrane.

25
cleavage furrow
first sign of cleavage; a small groove around the cell in the surface near the old metaphase plate.
26
cell plate
membrane-bounded, flattened sac located at the midline of a dividing plant cell; new cell wall forms during cytokinesis.
27
binary fission
asexual production by "division in half;"
28
origin of replication
site where the replication of a DNA molecule begins, consisting of a specific sequence of nucleotides.
29
cell cycle control system
a cyclically operating set of molecules in the eukaryotic cell that triggers and coordinated key events in the cell cycle.
30
G0 phase
a non-dividing state occupied by cells that have left the cell cycle.
31
cyclin
cellular protein that occurs in cyclically fluctuating concentration and that plays an important role in regulating the cell cycle.
32
density-dependent inhibition
phenomenon in normal animals cells that causes them to stop dividing when they come into contact with one another.
33
anchorage dependence
the requirement that a cell must be attached to a substratum in order to initiate cell division.
34
transformation
process that converts a normal cell into a cancer cell.
35
benign tumor
a mass of abnormal cells that have too few genetic and cellular changes to survive at another site; stay at original site.
36
malignant tumor
cells whose genetic and cellular changes enable them to spread to new tissues and impair the functions of one or more organs; cancer.
37
metastasis
spread of cancer cells to locations distant from their original site; dangerous.