Midterm I Flashcards
Endocrine signaling
Long distances through the bloodstream
eg adrenaline, estrogen
Paracrine signaling
short distances through diffusion
eg growth factors
Autocrine signaling
signaling and responding within the same cell
eg developmental decisions, cell division
Endoderm
(as part of the Blastocyst –> Gastrula)
cells lining inside of digestive tract and lungs
liver and pancreas cells
Ectoderm
(as part of the Blastocyst –> Gastrula)
cells in outer layer of skin
pigment cells
nerve cells in the brain
Mesoderm
(as part of the Blastocyst –> Gastrula)
cells in inner layer of skin
muscle, bone and red blood cells
Totipotent
can give rise to a complete organism
eg the fertilised egg
Pluripotent
can give rise to any of the 3 germ layers and therefore any cell of the body –> can’t on their own give rise to an entire organism
eg inner cell mass
Multipotent
can form a limited number of types of specialised cells
eg cells of germ layers
Epidermis
outer layer of skin, serves as water-resistant protective barrier
Dermis
supports the epidermis, also has cushioning effect
Epithelial cells
cells arranged in one or more layers
Basal Lamina
a specialised form of extracellular matrix found beneath all epithelial tissues
eg connects dermis to epidermis
Microtubule
helps maintain cell shape and internal structure
radiates out from centrosome
functions as tracks –> kinesin transports cargo toward + end ; dynein transports load to - end
Microfilaments
reinforces plasma membrane
associate with myosin to transport cargo
eg vesicles
Intermediate filaments
attached to cell junctions at cytoplasmic side –> anchoring results in structural continuity
Cadherins
calcium-dependent adherance proteins
only bind to others of the same type
Integrins
cell adhesion molecules that enable cells to adhere to extracellular matrix
also acts as receptors
Tight Junction
prevents the movement of substances through the space between cells
made up of: tight junction proteins
Adherens Junctions
cell - cell adhesion/anchoring
made up of: microfilaments, cadherin proteins
Desmosome
cell - cell adhesion/anchoring
made up of: intermediate filaments, cadherin proteins
Hemidesmosome
cell - extracellular matrix adhesion/anchoring
made up of: intermediate filaments, integrin
connects to basal lamina
Gap Junction
allows materials to pass directly from one cytoplasm to the next
made up of: channels (connexins)
Sensory Neurons
receiv and transmit info about the environment/internal physiological state