Midterm Exam Flashcards
Why is it recommended to access PubMed through the UMKC libraries webpage?
You get free access to the studies
Why do we suggest using “advanced” search box?
Searches can be saved
What is the difference between “AND” “OR” and “NOT”?
AND= articles with both terms listed (fewer articles)
OR= you get articles with either of the terms (more articles)
NOT= will eliminate the term
What is PMC?
PubMed Central: Articles funded by the National Institutes of Health Funds and are available to the public for free. This is reliability free.
What is MeSH?
Medical Subject Headings- used to focus search
In PubMed, where can you find MeSH terms?
Mesh database
A subset of systematic reviews; a method for systematically combining pertinent qualitative and quantitative study data from several selected studies to develop a single conclusion that has greater statistical power.
Meta-Analysis
In this type of study, the conclusion is statistically stronger than the analysis of any single study
Meta-Analysis
In a meta-analysis, why is the conclusion so strong?
The conclusion is statistically stronger than any single study, due to increased numbers of subjects, greater diversity among subjects, or accumulated effects and results
This type of study is used to establish statistical significance with studies that have conflicting results
Meta-Analysis
This type of study is used to develop a more correct estimate of effect magnitude
Meta-Analysis
This type of study is used to provide a more complex analysis of harms, safety data, and benefits
Meta-Analysis
This type of study is used to examine subgroups with individual numbers that are not statistically significant
Meta-Analysis
If a meta-analysis used studies in the form of ____ this would result in the highest level of evidence on the evidence hierarchy
Randomized control trials (RCT)
Greater statistical power, confirmatory data analysis, greater ability to extrapolate to general population effected (generalizable), considered and evidence-based resource
Advantages of Meta-Analysis
Difficult and time consuming to identify appropriate studies, Not all studies provide adequate data for inclusion and analysis, requires advanced statistical techniques, Heterogeneity of study populations
Disadvantages of meta-analysis
The studies pooled for reviewers should be similar in type (example- all randomized controlled trials)
This is a pitfall of:
Meta-analysis
We should ask ourself: Are the studies being reviewed all the same type of study or are they a mixture of different types?
In what type of study:
Meta-analysis
In a meta-analysis, the analysis should include:
Published and unpublished results to avoid publication bias
Does the meta-analysis include any appropriate relevant studies that may have had negative outcomes?
Yes
A document often written by a panel that provides a comprehensive review of all relevant studies on a particular clinical or health-related topic/question.
Systematic review
A document created after reviewing and combining all the information from both published and unpublished studies (focusing on clinical trials of similar treatments) and then summarizing the findings
Systematic review
Exhaustive review of the current literature and other sources (unpublished studies, ongoing research), Less costly to review prior studies than to create a new study, Less time required than conducting a new study, results can generalized and extrapolated into the general population more broadly than individual studies, more reliable and accurate than individual studies, considered an evidence-based resource
Advantages of systematic review
What are the disadvantages of a systematic review?
Very time consuming, and may not be easy to combine studies
