Midterm exam Flashcards
The effect of anesthesia on respiratory function depends on? (3)
Depth of general anesthesia
Patient’s preoperative respiratory condition
Presence of special intra-operative and surgical conditions
What are the 6 effects of anesthesia on respiratory function?
- Altered breathing pattern
- Decreased respiratory drive
- Decreased FRC
- Decreased lung compliance and increased resistance
- Increased V/Q matching
- Depressed of abolished cough reflex, decrease mucocilary escalator
Describe the breathing pattern change w/ anesthesia (light, deepening, deep and very deep anesthesia).
Light = respiration may be irregular
Deepening = regular, more than normal VT, prolonged forceful expiration
Deep = rapid, shallow breathing (panting)
Very deep = jerky, gasping, irregular
Name 3 general characteristic of the altered breathing pattern w/ anesthesia.
Chest wall asynchrony
Elevation of Vd/Vt (total dead space)
Monotonous breathing = loss of sigh or yawn
What is the normal sighing/yawning rate in an hour for an awake and healthy human?
What is the purpose of that normal yawning/sighing?
10/hour
Allow to take deep breaths = stimulates surfactant production
What causes the chest wall asynchrony w/ anesthesia?
Loss of intercostal ms contribution to inspiration
What causes decreased respiratory drive w/ anesthesia? (2)
- Progressive decrease in VE as anesthesia deepens
2. Decrease central chemoreceptor sensitivity = decrease VE response to CO2 stimulation
What happens when we bring lung closer to RV? (3)
- Increased airway closure
- Increased airway resistance
- Atelectasis and shunting
What are the causes of decreased FRC w/ anesthesia? (5)
- Supine position during Sx = diaphragm displaced up into the chest wall by the abdo viscera
- Reduced rib cage ms tone = no expansion of rib cage
- Increased abdo ms tone = contributes to lengthening of diaphragm
- Additional loss of ms tone w/ ms paralysis
- Manipulation of the lung/diaphragm
Why decreased lung compliance is related to reduced lung volume w/ anesthesia?
If FRC decreases, airways become more narrow which increased airway resistance
Why mucociliary action is reduced w/ anesthesia?
Anesthesia, intubation, pain meds, suppl. O2 all have a drying effect on the cilia which decrease its ability to beat
Why V/Q mismatching is increased w/ anesthesia? (3)
- Change in shape and motion of the chest wall = decreased thoracic excursion/maintained abdominal motion
- Inhaled anesthetics –> inhibition of hypoxic pulmonary vascoconstriction
- Non dependent regions (upper lung) better ventilated w/ mechanical ventilator
What are 8 the patient-related risk factors to have post-op complications?
- Pre-existing pulmonary impairment of neuromuscular illness (ASA > or = class 2)
- Increasing age: > 60 y.o
- Inactivity
- Active smoking (w/i last 8 weeks)
- Presence of skeletal deformities
- Malnutrition-serum albumin level < 30 g/L
- Noncompliant patient
- Obesity
T or F
There’s an increased rate of post-op pulmonary complication in COPD.
T
Pt in ASA class 2 are more at risk of post-op pulmonary complications, what are risky spirometry values? VC FEV1 DLCO VO2
VC < 50% predicted
FEV1 < 2L or 50% FVC
DLCO < 50% predicted
VO2 < 15mL/kg/min during exs
Why older pts are more at risk of post-op pulmonary complication? (2)
- Coexistent medical problems
2. Alterations in pulmonary function w/ age = increased closing capacity
Why is active smoking a patient-related risk for post-op pulmonary complications? (2)
- Reduces ciliary action
2. Irritation of airways w/ increased mucous production
What are the 2 surgery-related risk factors for post-op pulmonary complications?
- Type of Sx
2. Prolonged operative procedures
Classify the most risky cardioresp Sx to the least risky.
AAA > Thoracic > upper abdo > lower abdo > non abdo/non-thoracic
Diaphragm dysfunction is possible to occur during abdo/thoracic Sx:
- What is the consequence of this?
- What causes this?
- Is it reversible?
- Decrease FRC and ventilation in dependent (lower) lung zones
- Splanchnic/abdo receptor stimulation during Sx = inhibition of central drive/decrease phrenic motor input OR phrenic nerve irritation during Sx
- Yes, goes back to normal 1 week post-op
With duration of anesthesia, when does the risk for post-op complication becomes important?
Duration of anesthesia > 3 hrs
T or F
Higher risk of post-op complication w/ epidural/spinal anesthesia and video-assisted horoscopic surgery than general anesthesia.
F
Lower risk
Who am I?
Submammary incision extending from near midline to the 4th or 5th intercostal space at the misaxillary line.
Anterolateral thoracotomy
What are the ms cut in anterolateral thoracotomy? (3)
- Pectoralis major
- Serratus anterior
- Internal and external intercostals