Midterm Drugz Flashcards
Diazepam (Valium) MOA
Binds to benzodiazepine receptor which enhances the effects of GABA
Diazepam Indications and Contraindications
Indications: seizures, alcohol withdrawal, anxiety
Contraindications: sensitivity, CNS and respiratory depression,shock, coma, head injury
Diazepam Side Effects and Pregnancy Class
Side Effects: CNS and respiratory depression, ALOC, N/V, hypotension, drowsiness, headache
Class: D
Diazepam Dose and Route
SIVP, IO, IM
Adult: 5-10 mg
Peds: 0.3-0.5 mg/kg
Lorazepam (Ativan) MOA
Binds to benzodiazepine receptor which enhances the effects of GABA
Lorazepam Indications and Contraindications
Indications: seizures, agitation, anxiety, alcohol withdrawal
Contraindications: sensitivity, CNS and respiratory depression, hypotension
Lorazepam Side Effects and Pregnancy Class
Side effects: CNS and respiratory depression, ALOC, N/V, hypotension, drowsiness, headache, blurred vision
Class: D
Lorazepam Dose and Route
SIVP, IO, IM
Adult: 2-4 mg (max 4 mg)
Peds: 0.1 mg/kg (max 2 mg)
Midazolam (Versed) MOA
Binds to benzodiazepine receptor which enhances the effects of GABA
Midazolam Indications and Contraindications
Indications: seizures, sedation, psychosis
Contra: sensitivity, shock, coma, glaucoma
Midazolam Side Effects and Pregnancy Class
Side Effects: CNS and respiratory depression, ALOC, N/V, hypotension, drowsiness, headache
Class: D
Ketamine (ketalar) MOA
Alters perception of pain by blocking afferent impulses to the CNS
-anesthetic and analgesic
Ketamine Indications and Contraindications
Indications: pain, sedation, excited delirium
Contra: sensitivity, stroke, HTN, cardiac instability
Ketamine Side Effects and Pregnancy Class
Side Effects: HTN, increased HR, hallucinations, delusions
Class: not assigned
Fentanyl (Sublimaze) MOA
Opiate receptor agonist
-produces analgesia and euphoria
Fentanyl Indications and Contraindications
Indications: pain management, anesthesia adjunct
Contra: sensitivity
Caution with TBI
Fentanyl Side Effects and Pregnancy Class
Side Effects: CNS and respiratory depression, ALOC, N/V, Dysrhythmias, hypotension, delirium
Class: C
Fentanyl Dose and Route
Rapid IN, SIVP, IO, IM
1 mcg/kg (max 150 mcg)
Morphine (Raxonal) MOA
Opiate receptor agonist
- peripheral vasodilation effects
- decreases preload and afterload
Morphine Indications and Contraindications
Indications: moderate to severe pain, pulmonary edema, acute coronary syndrome
Contra: sensitivity, hypovolemia, hypotension, head injury, MAOI taken within 14 days
Morphine Side Effects and Pregnancy Class
Side Effects: CNS and respiratory depression, ALOC, N/V, Dysrhythmias, hypotension
Class: C