Midterm Drugs Flashcards

1
Q

Captopril

A

ACE inhibitor

“-pril”

Vasodilator

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2
Q

Enalapril

A

ACE inhibitor

“-pril”

Vasodilator

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3
Q

tPA (plasminogen actvtr)

A

activator of plasminogen

Thrombolytic

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4
Q

Clopidogrel

A

ADP receptor antagonist

Irreversible

“-gel” or “-grel”

Antiplatelet

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5
Q

Prasurgel

A

ADP receptor antagonist

Irreversible

“-gel” or “-grel”

Antiplatelet

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6
Q

Ticagrelor

A

ADP receptor antagonist

Reversible

“-gel” or “-grel”

Antiplatelet

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7
Q

Dobutamine

A

Adrenergic agonist

“A2,B1”

Adrenergic

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8
Q

Dopamine

A

Adrenergic agonist

D1

Adrenergic

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9
Q

Epinephrine

A

Adrenergic agonist

“A1,A2,B1,B2”

Adrenergic

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10
Q

Isoproterenol

A

Adrenergic agonist

“B1,B2”

Adrenergic

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11
Q

Norepinephrine

A

Adrenergic agonist

“A1,A2,B1”

Adrenergic

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12
Q

Eplerenone

A

Aldosterone receptor antagonist

“-one”

Vasodilator

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13
Q

Spironolactone

A

Aldosterone receptor antagonist

“-one”

Vasodilator

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14
Q

Brimonidine

A

Alpha agonist

“A1,A2”

“-ine”

Adrenergic

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15
Q

Clonidine

A

Alpha agonist

A2

“-ine”

Vasodilator

Adrenergic

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16
Q

Midodrine

A

Alpha agonist

non-selective

“-ine”

Adrenergic

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17
Q

Oxymetazoline

A

Alpha agonist

“A1,A2”

“-ine”

Adrenergic

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18
Q

Phenylephrine

A

Alpha agonist

non-selective

“-ine”

Adrenergic

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19
Q

Pazosin

A

Alpha blocker

A1

“-sin”

Vasodilator

Adrenergic

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20
Q

Phenoxybenzamine

A

Alpha blocker

non-selective

Adrenergic

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21
Q

Phentolamine

A

Alpha blocker

non-selective

Vasodilator

Adrenergic

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22
Q

Tamsulosin

A

Alpha blocker

A1

“-sin”

Adrenergic

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23
Q

Terazosin

A

Alpha blocker

A1

“-sin”

Adrenergic

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24
Q

Fondaparinux

A

Antithrombin catalyst

Inhibition of Factor Xa

Anticoagulant

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25
Q

Heparin (UFH)

A

Antithrombin catalyst

inhibition of thrombin

Anticoagulant

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26
Q

LMWH

A

Antithrombin catalyst

Inhibition of Factor Xa

Anticoagulant

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27
Q

Losarten

A

ARB

Vasodilator

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28
Q

Hydralazine

A

Arteriolar dilator

Vasodilator

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29
Q

Albuterol

A

Beta agonist

B2

“-lol”

Adrenergic

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30
Q

Atenolol

A

Beta blocker B1

“-lol”

Vasodilator

Antianginal

Adrenergic

Antiarrhythmic

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31
Q

Esmolol

A

Beta blocker

“-lol”

Vasodilator

Adrenergic

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32
Q

Metaprolol

A

Beta blocker

B1

“-lol”

Adrenergic

Antiarrhythmic

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33
Q

Pindolol

A

Beta blocker

“B1,B2”

“-lol”

Adrenergic

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34
Q

Propanolol

A

Beta blocker

non-selective

“-lol”

Vasodilator, Antianginal,

Adrenergic, Antiarrhythmic

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35
Q

Sotalol

A

Beta blocker

non-selective

“-lol”

Vasodilator, Antianginal,

Adrenergic, Antiarrhythmic

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36
Q

Cholestyramine

A

Bile Acid Binding Resin

Hypolipidemic

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37
Q

Colesevelam

A

Bile Acid Binding Resin

Hypolipidemic

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38
Q

Colestipol

A

Bile Acid Binding Resin

Hypolipidemic

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39
Q

Ranolazine

A

Block late sodium current

Antianginal

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40
Q

Diltiazem

A

Calcium blocker

benzothiazepine

Antianginal

Antiarrhythmic

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41
Q

Amlodipine

A

Calcium blocker (dihydropridine) “

“-pine”

Vasodilator

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42
Q

Clevidipine

A

Calcium blocker (dihydropridine) “

“-pine”

Vasodilator

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43
Q

Nicardipine

A

Calcium blocker (dihydropridine)

“-pine”

Vasodilator

44
Q

Nifedipine

A

Calcium blocker (dihydropridine)

“-pine”

Vasodilator

Antianginal

45
Q

Nimodipine

A

Calcium blocker (dihydropridine)

“-pine”

Antianginal

46
Q

Verapamil

A

Calcium blocker

(non-dihydropyridine)

Vasodilator

Antianginal

Antiarrhythmic

47
Q

Ezetimibe

A

Cholesterol absorption inhibitor

Hypolipidemic

48
Q

Aspirin

A

COX Inhibitor

Antiplatelet

49
Q

Fenoldopam

A

Dopamine agonist

D1

Vasodilator

Adrenergic

50
Q

Procainamide

A

Fast sodium blocker (Ia)

active state

Antiarrhythmic

51
Q

Fenofibrate

A

Fibrate

PPAR(alpha) agonist

Hypolipidemic

52
Q

Eptifibatide

A

GPIIa/IIIb inhibitor

derivative snake venom

Antiplatelet

53
Q

Tirofiban

A

GPIIa/IIIb inhibitor

“synthetic, non-peptide”

Antiplatelet

54
Q

Atorvastatin

A

HMG-CoA Reductase Inhibitor

“-statin”

Hypolipidemic

55
Q

Lovastatin

A

HMG-CoA Reductase Inhibitor

“-statin”

Hypolipidemic

56
Q

Pravastatin

A

HMG-CoA Reductase Inhibitor

“-statin”

Hypolipidemic

57
Q

Rosuvastatin

A

HMG-CoA Reductase Inhibitor

“-statin”

Hypolipidemic

58
Q

Simvastatin

A

HMG-CoA Reductase Inhibitor

“-statin”

Hypolipidemic

59
Q

Dipyridamole

A

Inhibits cGMP/cAMP PDE

Inc cGMP/cAMP

Antiplatelet

60
Q

Amiodarone

A

K+ blocker

Antiarrhythmic

61
Q

Bretylium

A

K+ blocker

Antiarrhythmic

62
Q

Ibutilide

A

K+ blocker

Antiarrhythmic

63
Q

Adenosine

A

K+ channel opener

Antiarrhythmic

64
Q

Minoxidil

A

K+ channel opener

Vasodilator

65
Q

Abciximab

A

MAB against platelet GPIIb/IIIa

Antiplatelet

66
Q

Carvedilol

A

Mixed blocker

“A1,B1,B2”

“ilol”” or ““alol”

Vasodilator

Adrenergic

Antiarrhythmic

67
Q

Labetalol

A

Mixed blocker

“A1,B1,B2”

“ilol”” or ““alol”

Vasodilator

Adrenergic

68
Q

Bethanechol

A

Muscarinic agonist

Cholinergic

69
Q

Muscarine

A

Muscarinic agonist

Cholinergic

70
Q

Pilocarpine

A

Muscarinic agonist

Cholinergic

Anticholinergic

71
Q

Atropine

A

Muscarinic antagonist

Anticholinergic

72
Q

Benztropine

A

Muscarinic antagonist

Anticholinergic

73
Q

Iptratropium

A

Muscarinic antagonist

Anticholinergic

74
Q

Oxybutynin

A

Muscarinic antagonist

Anticholinergic

75
Q

Propantheline

A

Muscarinic antagonist

Anticholinergic

76
Q

Scopolamine

A

Muscarinic antagonist

Anticholinergic

77
Q

Tiotropium

A

Muscarinic antagonist

Anticholinergic

78
Q

Tolterodine

A

Muscarinic antagonist

Anticholinergic

79
Q

Digoxin

A

Na-K ATPase blocker

Antiarrhythmic

Positive Inotropic

80
Q

Guanethidine

A

NE blocker/depletion

Adrenergic

81
Q

Amphetamine

A

NE displacement

Adrenergic

82
Q

Ephedrine

A

NE displacement

Adrenergic

83
Q

Nicotine

A

Nicotinic agonist

Cholinergic

84
Q

Varenicline

A

Nicotinic agonist

Partial (a4b2)

Cholinergic

85
Q

Hexamethonium (C6)

A

Nicotinic antagonist

Anticholinergic

86
Q

Trimethaphan

A

Nicotinic antagonist

Anticholinergic

87
Q

Isosorbide dinitrate

A

NO donor

“-nitrate” or “Nitro-“

Antianginal

88
Q

Isosorbide-5-mononitrate

A

NO donor

“-nitrate” or “Nitro-“

Antianginal

89
Q

Nitroglycerin

A

NO donor

“-nitrate” or “Nitro-“

Vasodilator

Antianginal

90
Q

Sodium Nitroprusside

A

NO donor

“-nitrate” or “Nitro-“

Vasodilator

91
Q

Apixiban

A

Oral direct Factor Xa inhibitor

Anticoagulant

92
Q

Rivaroxaban

A

Oral direct Factor Xa inhibitor

Anticoagulant

93
Q

Dabigatran

A

Oral direct thrombin inhibitor

Anticoagulant

94
Q

Inamrinone

A

PDE inhibitor

Vasodilator

Positive Inotropic

95
Q

Cilostazol

A

PDE-3 inhibitor

Inc cAMP

Antiplatelet

96
Q

Milrinone

A

PDE-3 inhibitor

Vasodilator

Positive Inotropic

97
Q

Laropiprant

A

PGD2 antagonist (used w/ niacin)

Hypolipidemic

98
Q

Streptokinase

A

Plasmin enhancers

Derived from Strep

Thrombolytic

99
Q

Urokinase

A

Plasmin enhancers

Derived from kidneys

Thrombolytic

100
Q

Aliskiren

A

Renin inhibitor

Vasodilator

101
Q

Bivalirudin

A

reversible, direct thrombin inhibitors

synth deriv of leeches

Anticoagulant

102
Q

Lepirudin

A

reversible, direct thrombin inhibitors

synth deriv of leeches

Anticoagulant

103
Q

Argatroban

A

small molec. Inhibitor thrombin

Anticoagulant

104
Q

Flecainide

A

Sodium blocker (Ic)

Antiarrhythmic

105
Q

Lidocaine

A

Very fast sodium blocker (Ib)

active/inactive state

Antiarrhythmic

106
Q

Warfarin

A

Vit K-epoxide reductase inhibitor

4-hydroxycoumarins

Anticoagulant

107
Q

Niacin

A

VLDL secretion inhibitor

Hypolipidemic