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BIOL 370 > Midterm content > Flashcards

Midterm content Flashcards

1
Q

microfilaments

A

polymers of actin

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2
Q

microtubules

A

polymers of tubulin

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3
Q

Kinesin moves:

A

outwards (+)

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4
Q

Dynein moves”

A

inwards (-)

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5
Q

Duty cycle non muscle myosin

A

0.5

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6
Q

duty cycle muscle myosin

A

0.05

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7
Q

Types of striated muscle

A

skeletal and cardia

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8
Q

thick filaments

A

myosin hexamers

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9
Q

thin filaments

A

alpha actin

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10
Q

Troponin

A

responds to Ca, moves tropomyosin out of the way

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11
Q

Tropomyosin

A

Covers actin binding sites

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12
Q

Z disk

A

protein plates where actin is attached

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13
Q

A band

A

thick filament length

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14
Q

I band

A

part of the thin filament that does not overlap

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15
Q

H zone

A

the thick filament section that does not overlap with the thin filament

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16
Q

Titin

A

springy anchors the thick filament to z disk

17
Q

Nebulin

A

twists around thin filament for structure

18
Q

Tropomodulin

A

Caps the - end of the thin filament

19
Q

CapZ

A

anchors + end of thin filament to the z disk

20
Q

Muscle myosin moves towards the:

A

+ end

21
Q

“twitch” vertebrate muscles are innervated by:

A

1 motor neuron

22
Q

What ensures depolarization in skeletal muscles

A

T-tubules - increase SA and allows for deep depolarization OR multiple innervations like tonic muscles

23
Q

DHPR opens:

A

Extracellular Ca

24
Q

RyR

A

physically linked to DHPR, RYR allows Ca to exit the SR

25
Q

Ca ATPase

A

Ca out of cell

26
Q

NaCaX

A

out of the cell

27
Q

SERCA pumps

A

Ca back into SR

28
Q

Troponin TnC

A

Binds to Ca

29
Q

Toponin TnI

A

Inhibitory: binds to actin

30
Q

Troponin TnT

A

binds to tropomyosin

31
Q

Why does summation happen

A

Increased calcium contraction when another stimuli is present

32
Q

When force was so high velocity is

A

zero

33
Q

Myogenic

A

contract in response to input from other muscle cells

34
Q

Cardiomyoctyes use what type of calcium releasee

A

Calcium induced, why? because RyR is not physically linked to DHPR

35
Q

Why is there sustained membrane potential in Cardiomyocytes

A

DHPR says open longer

36
Q

Myogenic uses

A

Gap junctions Neuro

37
Q

Neurogenic

A

stimulated by nerves

38
Q

parvalbumin

A

cytosolic calcium buffer that reduces calcium concentration in the cell

BIOL 370 (2 decks)

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