Midterm Chap 1-3, 7 & 8 Flashcards
Study of body function
Physiology
Study of body structure
Anatomy
Study of body surface by visualization and palpation (without “cutting”)
Surface anatomy
Study of anatomical structures visible to unaided eye, through “cutting”
Gross anatomy
Name the levels of organization, smallest to largest
Chemical - atomic, molecular Organelle Cellular Tissue Organ System Organelle
Basic structural and functional units of an organism
Cells
Group of cells that work together to perform a similar function
Tissues
Composed of two or more types of tissue
Organs
Related organs with common function
Organ system
Sum of all catabolic and anabolic chemical processes in the body
Metabolism
Equilibrium in the body
Homeostasis
What challenges homeostasis?
Physical insults (ie heat) Changes in internal environment Physiological stress (ie school or work)
Reverses a change in a controlled condition
Negative feedback (ie blood pressure)
Strengthens or reinforces change in controlled condition
Positive feedback (ie childbirth)
3 parts of feedback system are…
Receptor
Control center
Effector
System consists of skin and related structures (hair, nails, and glands)… Protects body, regulates temperature, and eliminates waste
Integumentary system
System made up of bones and joints, protects and supports the body, and houses cells that will become RBC and WBC
Skeletal system
System consists of skeletal muscles, smooth muscles, and cardiac muscles… Facilitates movement, maintains posture, and generates heat to maintain body temperature
Muscular system
System consists of brain, spinal cord, nerves and sensory organs… Senses and responds to body conditions through nerve impulses
Nervous system
System consists of hormone producing cells and glands scattered throughout the body… Regulates body through releasing hormones into the blood
Endocrine system
System consists of the heart, blood, and blood vessels… Carries blood and nutrients and regulates body temperature
Cardiovascular system
System consists of lymphatic fluid, lymph nodes, and lymphocytes (spleen, tonsils, and thymus gland also included)… Transports fats and proteins to cardiovascular system and protects against disease
Lymphatic system and immunity
System includes upper airways, trachea, bronchi and lungs
Respiratory system
System consists of esophagus, stomach, and intestines… Physical and chemical breakdown of food and eliminates waste
Digestive system
System includes kidneys, ureters, bladder and urethra
Urinary system
System includes ovaries, uterus, and vagina in females and the testes and penis in males
Reproduction system
Substance that cannot be broken down into simpler form
Chemical element
Units of matter
Atoms
What are found in the nucleus of an atom?
Protons and neutrons
What determines the atomic number?
Number of protons
What determines atomic weight?
Sum of protons and neutrons
Ions (ionic bonds) are formed when…
An atom gives up or gains an electron
Atoms that share electrons form…
Molecules
Free radicals are…
Electrically charged atom with unpaired electron in its outer shell
Unstable and highly reactive
Become stable by gaining or giving up electron
Atoms of molecules are held together by…
Chemical bonds
Cations are…
Positively charged ions that have given up (lost) an electron
Electron donors
Anions are…
Negatively charged ions that have gained an electron
Electron acceptors
What is the strongest chemical bond?
Covalent bonds
Covalent bonds are formed when…
Atoms of molecules share electrons
This type of bond is a weak interaction between hydrogen and adjacent electronegative atoms… They result from attraction of oppositely charged parts
Hydrogen bonds
Catalysts are…
Chemical compounds that speed up a reaction and are neither consumed or produced in the reaction
Name theses reactions:
- A + B -> AB
- AB -> A + B
- AB + CD -> AD + CD
- Synthesis, anabolism
- Decomposition, catabolism
- Exchange
Inorganic vs Organic molecules
Inorganic - simple molecules, usually lack carbon (ie water)
Organic - complex molecules, always contains carbon
What is pH?
Concentration of H+ in moles/l on scales of 0-14
pH < 7 acidic
pH > 7 base
Sugars, starches, glycogen, and cellulose containing carbon, hydrogen and oxygen that provide most of energy needed for life are…
Carbohydrates
_______ contain carbon, hydrogen and oxygen
Lipids
These lipids have 4 rings of carbon and include sex hormones, bile salts, some vitamins and cholesterol…
Steroids
This organic compound has a polar head and two non polar tails which makes it soluble in both water and fat…
Phospholipid
Proteins contain…
Carbon, hydrogen, oxygen and nitrogen
Most “human” organic compound
Made up of amino acids
______are proteins that speed up chemical reactions
Enzymes
DNA and RNA are…
Nucleic acids that make up our genetic code
Simple cells with no nucleus…
Prokaryotic cells
Complex cells that contain nucleus, plasma membrane and cytoplasm…
Eukaryotic cells
The “wall” of a cell, it is semipermeable and separates the cell’s internal environment from the external environment…
Plasma membrane
Gelatin-like substance that contains all of the cell’s components
Cytoplasm
The “brain” of the cell, contains DNA…
Nucleus
This transport process does not need energy, moves down/with concentration gradient…
Passive process
This transport process uses energy, goes against the concentration gradient…
Active process
Diffusion of water…
Osmosis
Facilitated diffusion is…
A passive process that requires a specific channel or carrier molecule
Spread of particles from areas of high concentration to areas of low concentration…
Diffusion
What affects diffusion?
Amount of substance Concentration gradient Temperature Surface area Distance
Net movement of water…
Osmosis
Concentration of salt solutions in the blood or elsewhere…
Tonicity
Isotonic, hypotonic, and hypertonic solutions…
Isotonic - normal shape
Hypertonic - greater concentration outside than inside cell
(shrinks)
Hypotonic - lesser concentration outside than inside cell (expands)
Endocytosis vs Exocytosis
Endocytosis - into the cell
Exocytosis - out of the cell
This component of the cell functions as a(n):
Intracellular fluid
Surrounding for organelles
Site of chemical reactions
Cytosol
Thinnest element of cytoskeleton, composed of proteins actin and myosin, and provide motion to the cell
Microfilaments
_______ help stabilize the position of organelles during mechanical stress and are the middle element of the cytoskeleton
Intermediate filaments
Largest element of the cytoskeleton, composed of the protein Tubulin, and helps determine the shape of the cell
Microtubules
Cilia vs Flagella
Cilia - short, hairlike projections that help move the cell
Flagella - longer than cilia, move the entire cell (sperm cell’s tail)
Site of protein synthesis…
Ribosomes
Synthesizes fatty acids and steroids, detoxifies certain drugs…
Smooth ER
Connects to nuclear envelope, series of flattened sacs, studded with ribosomes, produces various proteins…
Rough ER
“Packing” center, contains flattened membranous sacs called cisternae, modifies and packaging proteins for transport…
Golgi apparatus
Vesicles that contain powerful digestive enzymes…
Lysosomes
Small, detoxify toxic substances such as alcohol, found in liver…
Peroxisomes
Destroy unneeded proteins, found in cytosol and nucleus…
Proteasomes
“Powerhouse” of the cell, generates ATP, contains own DNA…
Mitochondria
Double membrane that separates the nucleus and cytoplasm…
Nuclear envelope
Opening in nuclear envelope, control movement of substance in and out of nucleus…
Nuclear pores
Spherical body that produces ribosomes…
Nucleolus
Hereditary units, control activities and cell structure…
Genes
Long molecules of DNA combined with protein molecules…
Chromosomes
Mitosis vs Meosis
Mitosis - cell replication
Meiosis - gamete replication
Phases of cell reproduction…
Interphase - cell is not dividing, cell replicates DNA
Prophase - chromatids pair up
Metaphase - chromatids align at metaphase plate
Anaphase - chromatid pairs split
Telophase - chromatids separate in two identical cells
The two major components the body can be divided into…
Axial and appendicular
Position used in discussions of the body, how it moves, its posture, etc…
Anatomical position
Ipsilateral means…
Same side
Two organization levels furnish basic building blocks required for the next higher level of the body structure which is cellular level
Chemical and organelle level
Lengthwise plane that splits body into left and right sides…
Sagittal plane
System responsible for maintaining homeostasis by opposing change
Negative feedback control system
Chemical compound that provides energy for use by the body…
ATP
Four major groups of organic substances in the human body…
Carbohydrates, lipids, proteins, and nucleic acids
This determines both the structure and function of cells…
DNA
Considered the engines of the cells…
Microtubules
This happens when membrane channels of adjacent plasma membranes adhere to each other…
Gap junctions
Internal supporting framework of the cell…
Cytoskeleton
Term meaning water loving…
Hydrophilic
This is located in the phospholipids and keeps the cell membrane from breaking too easily…
Cholesterol
Type of endocytosis meaning condition of cell eating…
Phagocytosis
Site of glycolysis…
Cytosol
This is when water and permeable solutes travel through a membrane by hydrostatic pressure….
Filtration
Type of solution where two fluids have same potential osmotic pressure…
Isotonic
This bone’s function is a vital process carried on by red bone marrow and involves blood cells…
Hematopoiesis
Bone type described cube or box shaped structures about as board as they are long…
Short bone
Only sesamoid bone in human skeleton…
Patella
This stores 98% of body’s calcium supply…
Skeletal system
Suture runs ear to ear…
Coronal suture
Bony landmark is a depression and often receives an articulating bone
Fossa
Bump on the back of your head…
External occipital protuberance
Anvil bone of the ear….
Incus
Breakfast 7, lunch 12, and dinner 5…
Vertebrae
Bony process meaning crow’s beak…
Coracoid process
Ribs _______ are true, _______ are false, and _______ are floating…
True 1-7
False 8-10
Floating 11-12
Coxal bone is made up of these three bones….
Ilium, ischium, and pubis
This is the Turk’s saddle…
Sella turcica
Narrow slit between adjacent parts of bones…
Fissure, ie supraorbital fissure
Foramen
Opening such as the jugular or optic…
Shallow depression…
Fossa, ie mandibular fossa
Furrow along bone surface…
Sulcus, ie intertubercular sulcus
Tubelike opening…
Meatus, ie external acoustic meatus
What are the 4 major elements of the body?
Carbon, hydrogen, oxygen and nitrogen
What is a controlled condition?
Variable such as blood pressure or body temp that is monitored by the feedback system
A receptor is an ________ pathway
Afferent; information flows towards the control center
Efferent pathways carry information _______
Away from the control center
Disruption in a controlled condition is called a…
Stimulus
- Intracellular fluid
- Extracellular fluid
- Interstitial fluid
- Within the cells
- Outside the cells
- Between the cells
Give example of positive and negative feedback systems…
Positive - childbirth
Negative - blood pressure
Prone vs supine…
Prone - face down
Supine - face up
Principal regions of the body include…
Head - skull and face
Neck - connects head and trunk
Trunk - chest, abdomen, pelvis
Upper limbs - shoulder, armpit, arm, forearm, wrist, hand
Lower limbs - buttock, thigh, leg, ankle, foot
Contralateral means…
Opposite side
Superficial vs deep….
Superficial - external, toward the surface
Deep - internal, away from the surface
Plane divides body into anterior and posterior portions….
Frontal or coronal plane
Plane divides body into superior and inferior portions…
Transverse or horizontal plane
This element is part of water and many inorganic molecules; used to generate ATP; can temporarily store chemical energy…
Oxygen
This element forms backbone chains of all organic molecules: carbohydrates, lipids, proteins, and nucleic acids…
Carbon
This element is a component of all proteins and nucleic acids…
Nitrogen
Constituent of water and most organic molecules; ionized form makes body fluids more acidic…
Hydrogen
Two atoms that share electrons equally form a….
Nonpolar covalent bond
Forms when sharing of electrons is unequal…
Polar covalent bond
What three types of lipids make up the plasma membrane?
Phospholipids - hydrophilic head; faces cytosol inside, ECF outside
Cholesterol
Glycolipids - appeal only in membrane facing ECF
What molecules are permeable across the membrane?
Permeable to nonpolar uncharged molecules, such as O2, CO2, and steroids
Impermeable to ions and large, uncharged polar molecules
Functions of proteins in the plasma membrane…
Ion channels, carriers, receptors, enzymes, linkers, and cell identity markers
Bone has greater length than width, contains a shaft and variable number of extremities…
Long bone; femur, phalanges, humerus
Bone has complex shape and cannot be grouped in other categories…
Irregular bone; vertebrae, hip bone and calcaneus
Bone is thin and composed of two parallel plates of compact tissue enclosing a layer of spongy bone tissue…
Flat bone; cranial bones, sternum, scapulae
Small bones located in joints between cranial bones…
Sutural bones
Narrow slit between adjacent parts of bone…
Fissure, superior orbital fissure
Tubelike opening…
Meatus, external acoustic meatus
Sharp, splendor projection…
Spinous process
Large projection…
Trochanter
Variably sized rounded projection…
Tubercle
Prominent ridge or elongated projection…
Crest