midterm Flashcards
Eugen Bleuler
said autism is a form of schizophrenia (“escape from reality”)
Leo Kanner
coined infantile autism
Hans Asperger
coined autistic personality disorder/autistic psychopathy (“little professors”)
Bruno Bettelheim
refrigerator mother theory
Bernard Rimland
suspected a biological/genetic explantion
Micheal Rutter
twin and family studies reveal genetic explanation
Lorna Wing
advocated for it to be considered a spectrum disorder
Ivar Lovaas
applied behaviorism to ASD
DSM-5 diagnostic criteria
1) persistent deficits in social communication and social interaction across contexts
2) restricted, repetitive patterns of behavior, interests, or activities
severity levels in the dsm
level 3 (very substantial support needed) level 2 (substantial support) level 1 (support)
central coherence theory
difficulty seeing the “big picture”
sally-anne task
where would she look for the marble etc
theory of mind
“mindblindness”, unable to understand/imagine others’ perspectives
rates of asd
1 in 59 kids (2018)
classifications on IEPs (6)
autism (AU) speech-language impaired (SI) learning disabled (LD) emotionally disturbed (ED) other health impaired (OHI) multiple disabilities (MD)
temporal lobe functions
language
amygdala functions
social orientation, response to reinforcing stimuli
frontal lobe functions
emotion expression, planning, organization, self-monitoring, inhibition of impulsivity, flexibility, working memory, executive functioning, information processing
CNVs
copy number variants - submicroscopic insertions and deletions in genome
concordance rate in monozygotic twins
60-90%
concordance rate in dizygotic twins
0-24%
concordance rate in siblings
risk of ASD diagnosis 15-20% higher than general population
brain volume differences
precocious growth in early postnatal life (18 months - 4 years) and then deceleration of growth in childhood and adolescence
white matter vs gray matter
white matter = nerve fibers + myelin
gray matter = nerve cells
environmental toxins which may increase risk (4)
exposure to pesticides
toxic metal exposure
certain pharmaceuticals
air pollutants
medications for asd
only medications used to treat symptoms (mood, anxiety, behavior, etc)
components of a diagnostic assessment
parent interview
observations in structured and unstructured play
gold standard asd assessment tools
assessment of adaptive functioning