midterm Flashcards

1
Q

what is research

A

process of investigation

involves examination of subject from diff points of view

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2
Q

reaserch is a goal directed process that is (), (). and ()

A

organized, objective reliable (reproducible)

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3
Q

research IS NOT

A

proving the efficacy of effectiveness of a treatmetn

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4
Q

besides being scientific and medical research, research can also be () () ()

A

questionnaires, surveys, studies that study (how people interact, habits)

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5
Q

why research 3

A

starting point for all medical progress
helped us understand avoiding risky behavirous to prevent disease

undersatn early diagnosis and appropriate treatment can prevent

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6
Q

reaserch literacy is the ability to waht

A

find, understand, critically evaluate research evidence for application in professional practice

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7
Q

reaserch capacity is the ability to

A

conduct research

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8
Q

method mean

A

systematic procedure for carrying out an acitivity

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9
Q

2 importance of research methods

A

to select therapeutic procedure for ur patient

to systematically compare effectivemess of new procedures

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10
Q

() () () are fundamental to any profession

A

experimental design, research methods, statistical analysis

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11
Q

ebm eveidence based medicine is the integration of 3 things

A

individual clinical expertise
best available external clinical evidence
patients values and expectations

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12
Q

from bottom up name the diff studies based on least reliable to most

A
least: background info/expert opionin
UNFILTERED INFO: case-series
case-controlled studies
cohort studies
RCT
FILITERD INFO: critically approved individual articles (article synopses)
critically appraised topics (evidence syntheses)
systematic reviews BEST
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13
Q

definition of ebm

A

the conscientious/careful explicit and judicious use of current best evidence in making decisions about the care of individual patients

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14
Q

5 steps to provide e-b care

A

1.ask an answerable question
2. searching for best evidence
3. critically aprasing the evidence
4 integrate the evidtence with our expertise and patients biology and values
5 evaluate our performance

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15
Q

the 5 A’s for ebm

A

asking, acquiring, appraising, alpplying assesing

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16
Q

problems with ebm

A

lack of skills (literature searches, critical analysis)
time consuming
evidence may be lacking
rct results may not be generalizable
potential of abuse by health care purchasers

17
Q

the first step in developing a research strategy is to

A

study previously published research literature

18
Q

issues with complimentary research

A
interrater/inter examiner reliability
funding
blinding is an issue
philosophical aspects (chi or subluxation)
limited number of researchers available
19
Q

what are included in clinical research process for a lets say drug to get from animals to humans

A
pre-clinical testing
investigational new drug application (IND)
phase 1, 2, 3
licensing
approval
post marketing studies
20
Q

what is phase 1 for

A

assess safety

21
Q

phase 2

A

test for effecetiveness

22
Q

phase 3

A

large scale testing

23
Q

what is used in pre clinical testing

24
Q

what part of clinical research process does chiro and accu not use

25
how many people are in each phaes
phase 1: 100 or less 2: 100-1000 people 3: over 1000 people
26
what order does chiro and accu research do
they do it backwards where we do post marketing studies first and then check effectiveness cause its been around a long time
27
chiro and accu research also tries to find the
mechanism of action
28
licensing part is for
approval to use (part of steps of research process)
29
approvale for
available for prescription
30
post-marketing studies for
special studies and long-term effectiveness/use
31
what are steps in actually researching
1. identify the research problem 2. create a research aims or hypothesis 3. review literature 4. select a design strategies 5. write research proposal 6. discuss issues about funding 7. obtain IRB approval 8. collect and collate data 9. analyze the datat and interpret finding or draw conclusions 10. write a report and share the findings INFORMATION DISSEMINATION 11. use the knowledge if applicable.knowledge translations
32
what 2 parts of the 11 part research do chiros and accus use
information dissemination nd use the knowladge (11 and 10)
33
what is the biggest thing about hypothesis
it has to be testable
34
what are 3 key things about literature review being thorough
1. determine level of theory and knowledge development through critical analysis 2. determine relevance of current knowledge 3. provide rationale for selecting the topic
35
when select/planning design strategy it needs to have a detailed outline on ()
how an investigation will take place. plan on collecting and utilizeing data
36
when looking at a design strategy checklist 3 thigns to condsider
confounders minimize bias enhancing the generalizability of results
37
when select/planning design strategy it needs to have a detailed outline on ()
how an investigation will take place. plan on collecting and utilizeing data
38
when looking at a design strategy checklist 3 thigns to condsider
confounders minimize bias enhancing the generalizability of results