midterm Flashcards
oxygen transport to tissues depends on
- cardiac output
- arterial oxygen concentration of hemoglobin
- metabolic requirements
room air has how much oxygen
21%
what is the goal of oxygen therapy
provide adequate transport of oxygen in the blood while decreasing the work of breathing and reducing stress on the myocardium
what is hypoxemia
decrease in arterial oxygen tension in the blood
manifestations of hypoxemia
- change in mental status
- dyspnea
- increased blood pressure
- change in heart rate
- dysrhythmia
- diaphoresis
- cool extremities
- central cyanosis (late sign)
what does hypoxemia lead to
hypoxia
what is hypoxia
a decrease in oxygen supply to the tissues
rapidly developing hypoxia may resemble what
alcohol intoxication
hypoxemic hypoxia
decreased oxygen levels in the blood resulting in decreased oxygen perfusion to the tissues
causes of hypoxemic hypoxia
- hypoventilation
- high altitude
- pulmonary embolism
- shunts (alveoli collapsed)
treatment for hypoxemic hypoxia
- increase alveolar ventilation
- oxygen
types of hypoxia
- hypoxemic
- circulatory
- anemic
- histotoxic
circulatory hypoxia
inadequate capillary circulation causes reduced tissue pressure (arterial oxygen remains normal)
causes of circulatory hypoxia
- decreased cardiac output
- local vascular obstruction
- low flow (shock, cardiac arrest)
treatment for circulatory hypoxia
identify and treat the cause
anemic hypoxia
decreased effective hemoglobin concentration causes decrease in oxygen carrying capacity of blood
(rarely accompanied by hypoxemia)
what causes a similar effect as anemic hypoxia
carbon monoxide poisoning
histotoxic hypoxia
a toxic substance that interferes with the ability of tissues to use available oxygen
ex. cyanide
oxygen toxicity
when too high an oxygen concentration (>50%) is administered for extended periods (>48 hours)
what causes oxygen toxicity
overproduction of oxygen free radicals
what can help defend against free radicals
vitamin E, C and beta-carotene
S&S of oxygen toxicity
- substernal discomfort
- dyspnea
- restlessness
- fatigue, malaise
flow rate of nasal cannula
1-6 L/min
>4 requires humidification