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Oral Pathology > Midterm > Flashcards

Midterm Flashcards

1
Q

Well-circumscribed, corticated, notched RL lesion below mandibular canal at mandibular angle

A

Stafne defect

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2
Q

Doughy, pitting 2cm swelling on anterior midline FOM

Young M = F

Slow growing, elevates tongue

A

Dermoid cyst

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3
Q

Etiology of squamous papilloma

A

Papovavirus

HPV 6, 11

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4
Q

Etiology of verruca vulgaris

A

Papovavirus

HPV 2, 4, 6, 40

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5
Q

Etiology of condyloma acuminatum

A

HPV 16, 18

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6
Q

Etiology of molluscum contagiosum

A

MCV Poxvirus

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7
Q

Anatomic sites of preference BCC/SS/Melanoma

A

BCC/SCC: Sun exposed or traumatized skin.

SCC: Lip/pinna
BCC: Never oral
Melanoma: BANS, females (lower limbs, calf), males (trunk, H&N, intrascapular)

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8
Q

Head and neck prognostic factors

A 
3% of cancers
Decreasing incidence
50% survival/5 years
SCC 90%, M > F
T = local tumor growth
N = LN
M = metastasis
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9
Q

Head and neck staging

A

Stage 1: T1NOMO 85% <2cm
Stage 2: T2NOMO 66% 2-4cm
Stage 3: T1-T3, N1MO 41%, >4cm
Stage 4: T4,N2-3,M1 9%, bone and MF spaces invaded

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10
Q

Oral hairy leukoplakia etiology

A

EBV related lesion in patients w/ HIV/AIDS, candidiasis

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11
Q

White lesion on lateral border of tongue, doesn’t rub off, thickened

“Balloon cells”, parakeratin hyperplastic epithelium. Nuclear beading

A

Oral hairy leukoplakia

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12
Q

Most common malignant neoplasm

A

Sinonasal SCC

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13
Q 
Vascular and fibrous neoplasm
Adolescent males due to hormonal influence
Epitaxis, nasal airway obstruction
Locally aggressive destruction
TX: Resection, embolization
A

Juvenile nasopharyngeal angiofibroma

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14
Q

Primitive neuroectodermal tumor
Small round blue cell tumor
Rapidly growing, ulcerated tumor
Radiographically destructive, poorly defined, “onion skin” periosteal reaction

A

Ewings sarcoma

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15
Q

Well circumscribed, unilocular, bowing of inferior cortex
Benign mesenchymal neoplasm
Adult female
Mandible PM/M

A

Ossifying fibroma

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16
Q

Asymptomatic pseudocyst w/ salivary parenchyma

A

Stafne defect

17
Q

Most common form of orofacial clefting

Sex difference?

A

Cleft lip nad palate 45%

M>F

18
Q

Most common form of syndromic clefting

A

van der Woude syndrome

19
Q

Diffuse, milky gray, folded edematous mucosa on BM in black adults/smokers

Stretching removes appearance, doesn’t rub off

A

Leukoedema

20
Q

Cleft lip pathogenesis

Seen where?

A

Failure of fusion of median nasal process + medial brachial arch of maxillary process

Maxillary laterals and canines

21
Q

Embryologic fissural cyst

NLD remnant

A

Nasolabial cyst

22
Q

NLC characteristics

A

Extraosseous
Unilateral 90% soft tissue cyst in upper lip
Can cause nasal obstruction/pain

23
Q

Cystic teratoma of entrapped embryonic germinal epithelium

HX: Keratin/hair/glands/skin

A

Dermoid cyst

24
Q

Reactive epithelial hyperplasia to epithelial damage in mucosa/gingiva/skin/genitals

A

Verruciform xanthoma

25
Q

Verruciform xanthoma etiology

A

HPV?
No association to metabolic disorders
Assoc. w/ LP/lupus/PV/SCC/GVHD/CHILD

26
Q

Warning signs for melanoma

A 
New pigmented lesion
Enlargement of mole
Color change mole
Itching mole
Bleeding, painful mole
27
Q

Prognostic signs for melanoma

A 
Thickness
Ulceration
Location - extremities better prognosis than H&amp;N
Clark level (depth) from 1-5
Treatment time 100% cure rate early
28
Q

ABCDs of lesions

A 
Asymmetry
Border irregularity
Color variation
Diameter >6mm
Expansion/enlargement
29
Q

H&N cancer pattern of metastasis

A

Invasive: Non-healing ulcer, indurated, fixated, submucosal neck mass
Distant: Lung>liver>skin>bone>brain
10-40% field cancerization

30
Q

Syphilis stages

A

1- Chancre: rubber button w/ ulcerated borders at anus
2-Condyloma lata: Maculopapular wart like cutaneous rash in palm or soles
3-Latent, gumma: Interstitial luetic glossitis tongue is premalignant

31
Q

Common in uncontrolled insulin-dependent diabetics and those who are ketoacidotic
Nasal obstruction/bloody nasal discharge/facial pain
Intraoral swelling of maxillary alveolar process

A

Mucormycosis

32
Q

Well circumscribed, unilocular, bowing of inferior cortex

Mandible PM/M

A

Ossifying fibroma

33
Q

Familial adenomatous polyposis syndrome - APC gene

Intestinal polyps
Osteomas
Epidermal cysts
Thyroid cancer or carcinoma
Supernumerary teeth
A

Gardner syndrome

34
Q

1 inherited bone disease due to type 1 collagen mutation

Osteopenia, bone fractures, blue sclera, opalescent teeth, joint hypermobility, hypoacusis, wormian bones

A

Osteogenesis imperfecta

35
Q

Greatest malignant potential, most common SN papilloma

A

Inverted papilloma

36
Q

Inverted papilloma characteristics

A

Lateral nasal wall/paranasal sinuses

<7% HPV 6/11/16

37
Q

Painless oral vesicles that rupture

A

Herpes zoster

38
Q

Herpes zoster info

A

HHV-3 is primary infection (varicella)

Latent in DRG. Secondary prodrome in skin/eyes with intense pain

Oral Pathology (1 decks)

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