Midterm Flashcards
Well-circumscribed, corticated, notched RL lesion below mandibular canal at mandibular angle
Stafne defect
Doughy, pitting 2cm swelling on anterior midline FOM
Young M = F
Slow growing, elevates tongue
Dermoid cyst
Etiology of squamous papilloma
Papovavirus
HPV 6, 11
Etiology of verruca vulgaris
Papovavirus
HPV 2, 4, 6, 40
Etiology of condyloma acuminatum
HPV 16, 18
Etiology of molluscum contagiosum
MCV Poxvirus
Anatomic sites of preference BCC/SS/Melanoma
BCC/SCC: Sun exposed or traumatized skin.
SCC: Lip/pinna
BCC: Never oral
Melanoma: BANS, females (lower limbs, calf), males (trunk, H&N, intrascapular)
Head and neck prognostic factors
3% of cancers Decreasing incidence 50% survival/5 years SCC 90%, M > F T = local tumor growth N = LN M = metastasis
Head and neck staging
Stage 1: T1NOMO 85% <2cm
Stage 2: T2NOMO 66% 2-4cm
Stage 3: T1-T3, N1MO 41%, >4cm
Stage 4: T4,N2-3,M1 9%, bone and MF spaces invaded
Oral hairy leukoplakia etiology
EBV related lesion in patients w/ HIV/AIDS, candidiasis
White lesion on lateral border of tongue, doesn’t rub off, thickened
“Balloon cells”, parakeratin hyperplastic epithelium. Nuclear beading
Oral hairy leukoplakia
Most common malignant neoplasm
Sinonasal SCC
Vascular and fibrous neoplasm Adolescent males due to hormonal influence Epitaxis, nasal airway obstruction Locally aggressive destruction TX: Resection, embolization
Juvenile nasopharyngeal angiofibroma
Primitive neuroectodermal tumor
Small round blue cell tumor
Rapidly growing, ulcerated tumor
Radiographically destructive, poorly defined, “onion skin” periosteal reaction
Ewings sarcoma
Well circumscribed, unilocular, bowing of inferior cortex
Benign mesenchymal neoplasm
Adult female
Mandible PM/M
Ossifying fibroma
Asymptomatic pseudocyst w/ salivary parenchyma
Stafne defect
Most common form of orofacial clefting
Sex difference?
Cleft lip nad palate 45%
M>F
Most common form of syndromic clefting
van der Woude syndrome
Diffuse, milky gray, folded edematous mucosa on BM in black adults/smokers
Stretching removes appearance, doesn’t rub off
Leukoedema
Cleft lip pathogenesis
Seen where?
Failure of fusion of median nasal process + medial brachial arch of maxillary process
Maxillary laterals and canines
Embryologic fissural cyst
NLD remnant
Nasolabial cyst
NLC characteristics
Extraosseous
Unilateral 90% soft tissue cyst in upper lip
Can cause nasal obstruction/pain
Cystic teratoma of entrapped embryonic germinal epithelium
HX: Keratin/hair/glands/skin
Dermoid cyst
Reactive epithelial hyperplasia to epithelial damage in mucosa/gingiva/skin/genitals
Verruciform xanthoma
Verruciform xanthoma etiology
HPV?
No association to metabolic disorders
Assoc. w/ LP/lupus/PV/SCC/GVHD/CHILD
Warning signs for melanoma
New pigmented lesion Enlargement of mole Color change mole Itching mole Bleeding, painful mole
Prognostic signs for melanoma
Thickness Ulceration Location - extremities better prognosis than H&N Clark level (depth) from 1-5 Treatment time 100% cure rate early
ABCDs of lesions
Asymmetry Border irregularity Color variation Diameter >6mm Expansion/enlargement
H&N cancer pattern of metastasis
Invasive: Non-healing ulcer, indurated, fixated, submucosal neck mass
Distant: Lung>liver>skin>bone>brain
10-40% field cancerization
Syphilis stages
1- Chancre: rubber button w/ ulcerated borders at anus
2-Condyloma lata: Maculopapular wart like cutaneous rash in palm or soles
3-Latent, gumma: Interstitial luetic glossitis tongue is premalignant
Common in uncontrolled insulin-dependent diabetics and those who are ketoacidotic
Nasal obstruction/bloody nasal discharge/facial pain
Intraoral swelling of maxillary alveolar process
Mucormycosis
Well circumscribed, unilocular, bowing of inferior cortex
Mandible PM/M
Ossifying fibroma
Familial adenomatous polyposis syndrome - APC gene
Intestinal polyps Osteomas Epidermal cysts Thyroid cancer or carcinoma Supernumerary teeth
Gardner syndrome
1 inherited bone disease due to type 1 collagen mutation
Osteopenia, bone fractures, blue sclera, opalescent teeth, joint hypermobility, hypoacusis, wormian bones
Osteogenesis imperfecta
Greatest malignant potential, most common SN papilloma
Inverted papilloma
Inverted papilloma characteristics
Lateral nasal wall/paranasal sinuses
<7% HPV 6/11/16
Painless oral vesicles that rupture
Herpes zoster
Herpes zoster info
HHV-3 is primary infection (varicella)
Latent in DRG. Secondary prodrome in skin/eyes with intense pain
