Midterm Flashcards
- Leukoplakia
- An intraoral white plaque that does not rub off and can not be identified as any well known entity.
- If it can be rubbed off, it is not Leukoplakia
- If it is easily recognizable as a well known entity, it is not Leukoplakia.
What are the five white lesions that CAN be scraped off?
- Materia Alba
- White coated tongue
- Burn (thermal, chemical, cotton roll, etc.)
- Pseudomembranous candidiasis
- Toothpaste or mouthwash overdose
Does white coated tongue cause pain, and how do you treat it?
- Asymptomatic
* Treatment is tongue scraping or brushing
How do you treat leukoplakia?
When in doubt, cut it out.
What could leukoplakia look like on the histology slide?
- Hyperkeratosis
- Dysplasia
- Carcinoma-in-situ
- Invasive squamous cell carcinoma
Where are the three most common locations of leukoplakia?
- Floor of mouth
- Tongue
- Lip
What is the best guide to potential progression of oral lesions?
Degree of dysplasia
What is the percentage transformation rate of severe dysplasia?
16%
• Mean transformation time 4.3 years
• Histologic grade significantly affected rate
• Excision significantly decreased rate
- Tori
- Torus Palatinus: 20-35%, 2F:1M, C=B
* Torus Mandibularis: 7-10%, M>F, C=B, 90% bilateral
- Inflammation or Irritation
Traumatic Ulcer
Pericoronitis
Periodontal Abscess (Parulis)
A.N.U.G.
- Fibroma
- MOST COMMON BENIGN NEOPLASM OF THE ORAL CAVITY
- Buccal mucosa > labial mucosa > tongue > gingiva
- Surgical excision
- Fordyce Granules
- Ectopic sebaceous glands
- 80% of the population
- yellowish white papules
- buccal mucosa > lips
- no treatment
- Hemangioma
- Benign proliferation of blood vessels
- 10 - 12% of children
- Clinically blanches under pressure
- Inflammatory Ulcer (Recurrent Aphthous Ulcer)
- Affects 20-25% of the population
- Non-keratinized, non-bound down mucosa
- 1-2 lesions, .5-1 cm in diameter
How do you treat hemangiomas?
• Treatment – surgery, laser, embolization, Clinical Observation, Removal, Sclerotherapy
How do you treat recurrent aphthous ulcerations?
• Treatment – Topicial Steroids
What is the etiology of recurrent aphthous ulcers?
• ETIOLOGY: “Different things in different people”. Autoimmune THEORY, Hypersensitivity THEORY, Stress THEORY, etc THEORY.
What are the prescriptions for recurrent aphthous ulcers?
• PRESCRIPTIONS: Aphthasol, Betamethasone, Temovate, Decadron, Lidex, Kenalog, Medrol, Etc.
- Papilloma
• Benign proliferaJon of squamous epithelium (HPV ?)
• Tongue > Soft palate
• Solitary pedunculated
wart-like
How do you treat papillomas?
• Treatment - Surgical excision
What are the variations of papillomas?
- Verruca Vulgaris (wart),
- Condyloma Acuminatum (Venereal wart),
- Focal Epithelial Hyperplasia (Heck’s Disease),
- Sinonasal Papillomas
- Epulis Fissuratum
Focal inflammatory hyperplasia at the flange of an ill-fitting denture. Single or multiple folds of tissue in the vestibule.
How do you treat epulis fissuratum?
Surgical excision, reline or remaking the denture
- Varicosities
Pretty normal
- Fissured Tongue
- Numerous grooves or fissures on the dorsal tongue, 2-6 mm deep.
- Cause ??? Heredity?
- 2 - 5% of the population, increasing with age
- Mild burning or soreness sometimes
- Treatment - Brush the tongue
- Geographic Tongue
- “Erythema Areata Migrans”, “Benign Migratory Glossitis”
- 1 - 3% of the population, 2F>1M
- Dorsal tongue, rarely ventral
- Asymptomatic with rare cases of sensitivity to hot or spicy foods
- No treatment
- Papillary Hyperplasia
- Denture papillomatosis
- 20% of the patients who wear their dentures 24 hours a day
- Hard palate, pebbly surface
- Asymptomatic
How do you treat papillary hyperplasia?
• Treatment - surgical excision (scapel, electro-, cryo-, laser-surgery) then reline or remake of the denture
- Herpes Viral Infection
Recurrent Herpes Simplex
• Almost ALWAYS on keratinized, bound mucosa (palate, attached gingiva)
• Symptoms are less intense
• Lesions begin as 1-3 mm vesicles
– Rapidly collapse to form a cluster of erythematous macules that coalesce and slightly enlarged
– Damaged epithelium is lost – Central, yellowish area of ulceration – Heals in 7-10d
- Acute herpetic gingivostomatitis: Initial exposure between 6 months - 5 years of age
- Recurrent herpetic infections: herpes labialis, intraoral recurrent lesions, herpetic whitlow, herpetic keratoconjunctivitis
What are the antiviral medications for herpes?
- Acyclovir 5% ointment (Zovirax), 15 gm tube, apply 5 times a day with fingercot at first symptom
- Acyclovir 200mg. capsules, dispense 50, 1 cap 5 x daily
- Famciclovir (Famvir) 125 mg tablets, bid for 5 days.
- Penciclovir 1% (Denavir) Cream, 2 gm tube, apply q2h.
- Prodromal stages is best time to start treatment (Use VIROXYN)
- Prophylaxis: Lysine 500 mg tab. QD
- Mucocele
- Rupture & spillage of saliva into the soft tissues
- Young adults, trauma related
- Lower lip - most common location
- Treatment - Surgical excision along with the feeder gland
- Scar Tissue
- Post trauma locations
- Post surgical locations
- Treatment - none
- Angular Cheilitis
• Causes: Reduced vertical dimension, salivary pooling, candidiasis
How do you treat angular cheilitis?
• Treatment: antifungals, increase the vertical dimension
- Lingual Tonsil
- Lymphoid hyperplasia on the posterior lateral borders of the tongue, bilateral
- Discrete 1 cm masses which enlarge and turn red with infection
- Treatment: none
- Hematoma
- Accumulation of blood within the tissues secondary to trauma
- Treatment: none
- Tobacco Pouch Keratosis
• Soft, fissured gray-white lesion of the mucosa located in the area of chronic snuff placement
• Histologic appearance varies based upon duration
• Treatment: Cessation of “dipping”
If use continues, results may progress from Dysplasia to Verrucous Carcinoma (cauliflower)
- Chronic Cheek Biting
- Morsicatio buccarum, labiorum, linguarum
- 2F:1M
- Irregular ragged white mucosa
- Treatment: none or bite guard
- Lichen Planus
Oral lichen planus must be differentiated from lichenoid drug reactions, and there are dozens of drugs that can cause it.
• Chronic mucocutaneous disease
• Middle aged, 3F:2M
• Skin lesions: purple, pruritic, polygonal papules
• Oral lesions: Reticular (Striae of Wickham), Erosive
What are the two forms of lichen planus?
Reticular and Erosive
How do you treat lichen planus?
• Treatment: Steroids
• Aphthasol 5%, 5 gm tube, apply to ulcer
• Betamethasone (Celestone) Syrup, dispense 8
oz., 1 tsp qid, gargle & expectorate.
• Temovate .05% ointment, 15 tube
• Decadron Elixir 0.5mg/5ml, Rinse & expectorate.
• Lidex 0.05% ointment or gel
• Medrol Dose pack
- Buccal Exostoses
- Bony protuberances on the buccal of the mandible and/or maxilla
- Treatment: Removal only with chronic repeated trauma or preprosthetic surgery
- Amalgam Tattoo
- Implantation of dental amalgam into oral soft or hard tissue
- Black, blue or grey in soft tissue tattoos
- May be radiopaque
- Treatment: none, however biopsy may be necessary to rule out melanoma
- Oral Melanotic Macule
• Focal Melanosis (“oral freckle”) • Solitary well-demarcated tan to dark brown macule, 1-7 mm • 2F:1M • Lower lip > buccal mucosa > gingiva • Treatment: none, however biopsy may be indicated to rule out melanoma
- Median Rhomboid Glossitis
- Central papillary atrophy of the tongue
* Asymptomatic erythematous zone in the midline posterior dorsal tongue
How do you treat median rhomboid glossitis?
• Treatment: antifungals and brushing of the tongue
- Black Hairy Tongue
Condition is usually asymptomatic, but occasional patients complain of:
Gagging sensation, Bad taste, Halitosis, Esthetics
- Smooth Red Tongue
- Causes: Pernicious anemia, Medications, Avitaminosis
- Symptoms: burning and pain
- Treatment: find the underlying cause and stop it
- Epidermoid Cyst
- Skin cysts associated with inflammation of a hair follicle • Oral cysts occur in the midline of the floor of the mouth • Slow growing, painless, rubbery mass
- Treatment: Surgical removal
- Lipoma
- Benign tumor of fat
- Skin lesions: trunk and proximal portions of the extremities
- Oral lesions: buccal mucosa > tongue > floor of the mouth > lips
- Yellowish soft nodular mass
- Treatment: Surgical excision
What are the characteristics of white lesions?
Thickened epithelial covering - Hyperkeratosis, acanthosis, dysplasia, carcinoma Decreased vascularity - Anemia Increased collagen - Submucous fibrosis
When we are describing lesions, what five characteristics should we describe?
- Size
- Morphology
- Location
- Texture
- Color
- A fibroma is a 2 mm sessile nodule on buccal mucosa, smooth surfaced, and pink in color