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IB 117 Ethnobotany > Midterm > Flashcards

Midterm Flashcards

1
Q

Endogenous acetylcholine effects which site(s)?

A

muscarinic, ganglionic, somatic motor

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2
Q

Muscarine effects which sites?

A

muscarinic

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3
Q

Pilocarpine effects which sites?

A

muscarinic (main), ganglionic (mild)

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4
Q

Arecoline effects which sites?

A

muscarinic, ganglionic

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5
Q

Physostigmine effects which sites?

A

muscarinic, ganglionic, somatic motor

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6
Q

Nicotine effects which sites?

A

ganglionic, somatic motor

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7
Q

Lobeline effects which sites?

A

ganglionic somatic motor

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8
Q

Endogenous norepineohrine effects which sites?

A

adrenergic

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9
Q

Ephedrine effects which sites?

A

adrenergic

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10
Q

Cocaine effects which sites?

A

adrenergic

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11
Q

Endogenous ach mechanism of action?

A

direct agonist

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12
Q

muscarine mechanism of action?

A

direct agonist

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13
Q

arecoline mechanism of action?

A

direct agonist

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14
Q

physostigmine mechanism of action?

A

inhibits the enzyme that breaks down ach

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15
Q

nicotine mechanism of action

A

direct agonist

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16
Q

lobeline mechanism of action

A

direct agonist

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17
Q

endogenous norepinephrine mechanism of action

A

direct agonist

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18
Q

ephedrine mechanism of action

A

direct agonist & also increases the release of norepinephrine from nerve terminus

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19
Q

cocaine mechanism of action

A

norepinephrine re-uptake inhibitor

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20
Q

pilocarpine mechanism of action

A

direct agonist

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21
Q

Scopolamine, atropine, ipatropium effects which sites?

A

Muscarinic

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22
Q

d-tubocurarine effects which sites?

A

ganglionic, somatic motor

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23
Q

botulinum toxin effects which sites?

A

muscarinic, ganglionic somatic

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24
Q

reserpine effects which sites?

A

adrenergic

25
Q

nicotine (high doses) effects which sites?

A

ganglionic

26
Q

nicotine (high doses) mechanism of action

A

Direct antagonist causing persistent depolarization that causes receptor to shut down

27
Q

reserpine mechanism of action

A

damages vesicles that contain catecholamines and tryptamines in nerve terminus

28
Q

botulinum toxin mechanism of action

A

decreases relealse of ach from nerve terminus

29
Q

d-tubocurarine mechanism of action

A

direct antagonist at nicotonic receptors

30
Q

scopolamine, atropine, ipatropium mechanism of action

A

direct antagonist

31
Q

increased heart rate, dialted pupils, decreased GI motility, increased sweating

A

endogenous sympathetic response

32
Q

increased heart rate, dilated pupils, decreased GI motility

A

Ephedrine, cocaine

33
Q

increased heart rate, dilated pupils, increased mouth secretions, decreased GI motility, decreased sweating

A

Atropine, scopolamine

34
Q

normal, heart rate, pupils, moth secretion and GI motility

A

Endogenous parasympathetic response

35
Q

decreased heart rate, constricted pupils. increased mouth secretions, increased GI motility, increased sweating

A

muscarine, pilocarpinem arecoline, physostigmine

36
Q

endogneous seratonin mechanism of action

A

direct agonist

37
Q

endogenous DMT mechanism of action

A

direct agonist

38
Q

DMT-Psychotria viridis mechanism of action

A

direct tryptamine agonist

39
Q

LSD mechanism of action

A

direct agonist, re-uptake inhibitor, indolemine

40
Q

Lysergol from Calviceps purpurea mechanism of action

A

direct tryptamine agonist, indolemine

41
Q

Psilocybin & psilocin

A

direct tryptamine agonist, indolemine

42
Q

Mescaline from Lophophora & Echinopsis

A

Direct tryptamine agonist, phenethylamine

43
Q

MDMA (ectasy)

A

Direct agonist, phenethylamine

44
Q

MDA

A

Direct agonist, phenethylamine

45
Q

Ibogaine from Tabernanthe iboga

A

Direct tryaptamine agonist & kappa opioid receptor agonist

46
Q

Hyperforin from Hypericum perforatum

A

re-uptake inhibitor

47
Q

harmine, harmalie from Banisteriopsos caapi

A

Re-uptake inhibitor (MAO)

48
Q

Gabtril

A

GABA re-uptake inhibitor

49
Q

Valerian

A

GABA direct agonist

50
Q

Kava

A

GABA agonist

51
Q

Thujone

A

GABA antagoist

52
Q

Picrotoxin

A

GABA antagonist

53
Q

Illex paraguariensis

A

Contains chllorogenic acids

54
Q

Forskalin

A

increases adenylate cyclase enzyme

55
Q

caffeine

A

blocks adenosine receptor

56
Q

cathinone

A

increase # of NT from nerve terminus

57
Q

Methamphetamine and other derivatives

A

Increase release of NT from nerve terminus

58
Q

bromocriptine & pergolide

A

direct agonist

59
Q

salvinorin A

A

kappa opioid receptor agonist

IB 117 Ethnobotany (2 decks)

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