Midterm 2 Flashcards
what provides energy for exercise?
triglycerides and glycogen
What is cardiovascular disease?
disease of the heart and blood vessels
CVD includes:
heart disease, high blood pressure, heart attacks, and strokes
what percentage of deaths are caused by CVD in Canada
30%
how much does CVD cost the Canadian economy a year
over 20.9 billion
what is Atherosclerosis ?
An inflammatory response to injury within the artery walls
what causes inflammation due to action of the immune system. (Atherosclerosis)
Lipid and Fibrous material deposits within the arterial wall.
What effects does Atherosclerosis cause
Reduces elasticity of blood vessels and eventually blocks blood flow
Blockage of blood flow to heart leads to a:
heart attack
blockage of blood flow to brains leads to:
stroke
5 step process of atherosclerosis
- fatty streak formation
- plaque accumulation
- fibrous cap formation
- fibrous cap rupture
- heart attack
Risk factors for CVD
- age
- gender
- bodyweight
- blood pressure
- high fat diet
saturated fat
fatty acid with maximum amount of hydrogens
monounsaturated fat
fatty acid missing 2 hydrogens, has a double bond
polyunsaturated fat
has 2 or more double bonds, lacks 4 or more hydrogens
Saturated and trans fats___ risk of heart disease
increase
Omega 3 and omega 6 polyunsaturated fats ___ risk of heart disease
decrease
how do omegas, and saturated fats have different effects?
affect type and amount of lipoproteins, triglycerides, and cholesterol differently
what occurs when chylomicrons are turned into HDL’s. Density, size, TG (triglycerides), Cholesterol
Density: increase
Size: decrease
TG: decrease
Cholesterol: increase
Chylomicrons
largest and most dense
transport lipids from the small intestine to the rest of the body.
VLDL (very low density lipoproteins)
lipoprotein made by the liver cells to transport lipids to various tissues in the body
LDL (low-density lipoprotein)
derived from VLDL’s as vldl triglycerides are removed and broken down: composed mainly of cholesterol
HDL (high density lipoproteins)
transports cholesterol back to the liver from the cells: composed mainly of protein
difference between HDL and LDL
LDL cholesterol is the cholesterol that is linked to heart disease whereas HDL represents cholesterol that is returning to the body. High HDL is a good thing whereas high LDL is not.
What increases LDL’s
saturated fats and trans fats
what increases VLDL’s
added sugars
What lowers HDL levels
trans fats
where do we get cholesterol from?
animal foods (meat, milk, eggs)
what makes cholesterol
our liver
dietary cholesterol, is usually not associated with…
blood levels of cholesterol
Omega 6 fats decrease
LDL’s
What do Omega 3 polyunsaturated fats do (regulate)
affect cell function
eating Omega 3’s helps:
- infant brains develop
2. prevent cognitive decline with age
Omega 3’s help decrease risk of CVD by: (3 things)
- improve blood lipid levels
- decreases blood clotting
- resolves inflammation
omega 3’s are found most commonly in:
sardines, salmon, trout, herring, and mackerel
what are the 2 kinds of long chain omega 3’s, and how long are they/how many d bonds.
- EicosapentaenoicAcid (EPA) (20:5)
2. Docosahexaenoic Acid (DHA) (22:6)
how many servings of fish should we have per week?
at least 2
what other foods can contain Omega 3’s
- eggs fortified with DHA
- micro encapsulated fish oil in milk and yogurt
- what does ALA stand for?
- what is it?
- where can it be obtained?
- Alpha-linoleic acid
- is an essential omega 3
- flax, canola, soy, walnut oil
can our bodies convert ALA into DHA and EPA?
yes, but conversion isn’t very efficient
what happens if too many omega 3’s are consumed?
can lead to dysfunction of the immune system and weight gain.
what do low fat products usually use instead?
carbohydrates
difference and similarity between fat substitutes and fat.
similar structure, but isn’t absorbed by the body.
what does Olestra do and symptoms do it cause?
may cause GI discomfort, bloating, and diarrhea.
- reduces absorption of fat soluble vitamins
- not approved in Canada
How to choose fat wisely, list 3 things to avoid.
limit cholesterol, trans fats, and saturated fats
(lower fat cuts, chicken with no skin, vegetarian one time a week, low fat dairy
how to choose fats wisely: list 2 things to increase
mono and polyunsaturated fats
more plant oils for salad dressings and baking
how to get more omega 3’s in your diet
(use more flax seed, eat more fish, more leafy greens)
how to watch your total fats?
- bake, broil, roast, instead of fry
- limit amount of butter
what part of the plant is coffee made from?
the seed
whats in coffee?
caffeine, phenolic substances, oxidizers
what contains the most caffeine, and what contains the least
drip brewed has most caffeine, and chocolate has the least.
some physical effects of caffeine?
irritability, restlessness, insomnia, and heart palpitations
caffeine withdrawal symptoms
headache, fatigue, drowsiness, irritability, depression. may increase with repeated use.
coffee facts: where is it absorbed and how long does it take?
absorbed in the small intestine in about 44m
how can caffeine cross the blood brain barrier?
it is sufficiently lipophilic
how long does it take caffeine to leave your body and what removes it?
excreted by the kidneys in 8-10 hours after consumption
caffeine increases bp for…
non regular users
doesn’t necessarily increase bp for…
regular users
Kahweol and cafestol increase…
LDL levels in the blood
kahweol and cafestol hare removed by
coffee filters
caffeine intake recommendations for pregnant women and other adults?
w: 300mg
O: 400mg
what percentage of ingested antioxidants come from coffee?
66%
what do antioxidants do?
they reverse oxidation and repair cell damage
what is oxidation?
when electrons are taken off of atoms, can damage cells, and their DNA
- creates free radicals
what kind of coffee has highest amounts of antioxidants?
medium roasted coffee
confounding variables: coffee drinkers are more likely to..
smoke and drink alcohol
moderate intake of coffee, due to___, helps decrease..
- antioxidants
2. t2 diabetes, some cancers, liver disease, parkinson’s
some concerns of impact by caffeine are:
sleep, mental health, pregnant women, bone health
Black tea: leaves are picked, ___, and dried
oxidized
what is in tea? 3 things
caffeine, antioxidants, tannins
what is Catechin? (tea)
- a polyphenol
- protects against oxidative stress
- highest content in white and green teas
what is L-theanine?
a non-protein amino acid derivative
what are tannins: can bind___ in the digestive tract to inhibit absorption
non-heme iron
too much tea can cause:
deficiency anemia
Health effects of tea regarding blood pressure
decrease blood pressure by protecting blood vessels
Health effects of green tea
may help with weight maintenance
health effects of tea regarding bones and teeth
may prevent age related bone decay and dental (caries) cavities
why are health effects of tea inconsistent?
levels of antioxidants and confounding variables affecting it
Amino acids are composed of:
a hydrogen atom, acid group, and unique side chain
how many amino acids are there?
20
what are essential amino acids and how many are there
9, our body cant make them and have to be obtained through diet
what are non essential amino acids and how many are there?
11, our bodies can make them through transamination
Essential amino acids: HILLMPTTV
Histidine Isoleucine Lysine Methionine Phenylalanine threonine Tryptophan Valine
rhyme to remember essential AA’s: HILLMPTTV
Hi I Like Leaves Meat Protein that tastes vgood
what is a peptide bond?
forms between the acid group of one AA and the nitrogen group of another.
peptide=
amino acids attached using a peptide bond
2 amino acids =
dipeptide
a few amnio acids (4-20)=
oligopeptide
a lot of amnio acids =
polypeptides
proteins are made from___
1 or more polypeptide strands