Midterm 2 Flashcards
what is the bone support function ?
it supports tissues and provided attachment points for tendons of skeletal muscles
what is the bone protection function?
it protects internal organs
how does bone maintain mineral homeostasis?
it stores and maintains homeostatic control of the blood concentration of calcium phosphate in bone mineral
what bone marrow produces blood cells ?
red bone marrow
how does bone store triglyceride?
bone stores energy in the form of triglycerides in yellow bone marrow/adipose cells
what are 6 functions of bone?
- support
- protection
- assistance in movement
- mineral homeostasis
- blood cell production
- triglyceride storage
what is compact bone?
organized into Haversian systems/osteon on the “perimeter/lining” of bone
what is spongy bone ?
thin columns of bone called trabeculae on the “inside” of bone
osteogenic cells origin ?
mesenchymal stem cells (MSCs)
osteogenic cells location ?
periosteum
osteogenic cells function ?
to become more differentiated to form osteoblasts
osteoblasts origin?
osteogenic cells that have differentiated
osteoblasts location?
bone surface/lining and bone itself
osteoblasts function?
forms new bones + adds growth to existing bone tissue
osteocytes origin?
osteoblasts that were encased in mineralized matrix
osteocytes location?
reside in lacunae in close proximity to blood vessels
osteocytes function?
maintaining strength and health of the bone matrix
osteoclasts origin?
derived from the fusing of many monocytes (blood cells)
osteoclasts location?
bone surface/lining and bone itself
osteoclasts function?
break down/reabsorb bone
what is an osteoid?
unmineralized bone matrix
what are the two types of bone formation?
- intramembranous ossification
- endochondral ossification
flat bones of skull + mandible develop via what bone formation type?
intramembranous ossification
endochondral ossification
is a type of skeletal development in which hyaline cartilage is replaced by bone
long bones are developed via what bone formation type?
endochondral ossification
growth plate function?
allows for growth length-wise until puberty
what happens to the epiphyseal plate/growth plate at puberty?
the cartilage gets replaced by bone
bone remodeling
is when bone is removed and new bone is laid down in the same location
bone modeling
is when bone is removed in one place and laid down in another
what is a sesamoid bone?
a bone that is embedded within a muscle or tendon near joint surfaces
what is an example of a sesamoid bone?
patella
fracture healing steps…
- initial site of fracture = forms fracture hematoma
- Fibrocartilaginous callus forms
- bony callus forms
- bone remodeling
what is osteoporosis ?
when the balance between new bone formation and bone breakdown is disrupted —> bone lose occurring
how does the body maintain a normal body temp?
through thermogenesis (as a muscle contracts it generates heat)
what are the 4 properties of muscle tissue?
- excitability
- contractility
- extensibility
- elasticity
what are fascia in CT?
a band of CT that surrounds muscle or other organs
what is the epimysium in CT?
CT that encircle the entire muscle
what is the perimysium in CT?
CT that surrounds groups of 10-100 muscle fibers
what is the endomysium in CT?
surrounds and separates individual muscle fibers within fascicles
what are fascicles in CT?
bundles of muscle fibers
what is a tendon?
a band of CT that attaches a muscle to bone
what is the aponeurosis?
tendons that extend in a broad flat layer = how occipitofrontalis muscles attach to the skull
what is a muscle fiber?
a muscle cell
what is a myoblast?
embryonic cells that fuse to form muscle fibers
what are satellite cells ?
myoblast-derived cells that can result in some muscle regeneration
what is the sarcolemma?
plasma membrane of muscle fibers
function T tubules?
allow for conduction of the nerve impulse received at the NMJ all the way through the fiber
what is the sarcoplasm?
cytoplasm of muscle
what is a myofibril ?
small special contractile structures that run through the sarcoplasm of muscle fibers
what is the SR?
the endoplasmic reticulum of muscle fibers
what are the 4 properties of muscle tissue?
1.excitability
2. contractibility
3. extensibility
4. elasticity
what are fascia ?
a band of CT that surrounds muscle or other organs
what is the epimysium ?
CT that encircle the entire muscle
what is the perimysium ?
CT that surrounds groups of 10-100 muscle fibers
what is the endomysium ?
surrounds and separates individual muscle fibers within fascicles
what are fascicles?
bundles of muscle fibers
what is a tendon?
a band of CT that attaches a muscle to bone
what is the aponeurosis ?
tendons that extend in a broad flat layer = how occipitofrontalis muscles attach to the skull
what is a muscle fiber ?
a muscle cell
what is a myoblast ?
an embryonic cell that fuse to form muscle fibers