Midterm 2 Flashcards
(142 cards)
In Ritvo’s/CAMH study, inclusions involved:
Age range:
BDI-II score:
Language fluency in:
Confirmation of psychiatric disorder of MDD done through process of:
18-30 years (youth)
BDI-II of at least mild severity (equal or above 14); no upper limit
English
Mini interview
Trial exclusion criteria for online mental health study by Ritvo involved:
Individuals currently receiving: _________
Meeting ______ criteria for _________ in the past ___ months
Clinically significant _______ defined as imminent intent, or attempted suicide in the last ______ months
Comorbid diagnosis: 5 items
Weekly structured psychotherapy
DSM-V criteria for severe alcohol/substance use disorder in the past 3 months
Clinically significant suicide ideation, attempted in last 6 months
BPD, schizophrenia, bipolar disorder, OCD
An issue with the BDI-II is that it’s ______-ogenic
Depressogenic
What are some aspects of BDI-II’s curriculum?
Sadness, pessimism, past failure, loss of pleasure, guilty feelings, punishment feelings, negativity & self negativity, agitation, de-vitalization, changes in sleep/diet, tiredness
What are the similarities and difference in treatment between control and experimental group in Ritvo’s study on online mental health?
Patients in both groups received standard psychiatric care available at CAMH.
Experimental subjects additionally received the online CBT-MM intervention.
What is the difference between intention-to-treat and per-protocol analyses?
In ITT, all subjects are assessed (including drop-outs) whereas with PP only subjects who receive adequate proportions of intervention are assessed (i.e., takes into account only those who make it through the whole study)
What was the effect size in the within group findings (Cohen’s d) from Ritvo’s study on depression/online mental health?
d = 1.90, i.e., very large
What was the scale for anxiety used in Ritvo’s study on online mental health?
What was the effect size in the within group findings for anxiety from Ritvo’s study on online mental health?
Beck Anxiety Inventory
ES: Cohen’s d = 1.55; very large
Which other 2 scales were used in Ritvo’s online mental health study (other than ones mentioned first for depression and anxiety), and what were each of their effect sizes?
Hamilton Depression Rating Scale; d = 1.60
Quick Inventory of Depressive Symptomatology; d = 1.38
What percent symptom reductions were found in Ritvo/CAMH (2019)’s study?
53.4%
What differentiated CAMH online mental health study from Thase et al., 2018?
Dealt with a medicated population (per standard care CAMH) and 54.5% of patients were put on E-CBT for 24 sessions, whereas the other study had 7 sessions of E-CBT for 43% of the patients
What was unique about Ritvo/CAMH’s trial?
Diagnosed MDD, combined standard psychiatry with e-CBT, no reduction/withdrawal from drugs, significant remission %, all patients diagnosed by CAMH psychiatrists with confirmation from mini interview, blinded HDRS assessments, and no limit on depression severity
Ritvo/CAMH study:
N = _____ subjects in severe depression at baseline
N = _____ subjects in remission at follow up
% reduction was ____%, but overall mean reduction of ____% at follow up
N = 10; N = 5, 66%, 37.2%
Ritvo/CAMH study:
N = ___ subjects in moderate depression at baseline
N = ___ subjects in remission at follow up
Mean reduction of ___%, but overall mean reduction of ___%
N = 6, N =5, 72%, 61%
Ritvo/CAMH study:
N = __ subjects in mild depression at baseline
N = __ subjects in remission at follow up
Mean reduction of ____%, overall reduction of ___%
N = 3, N = 2, 66.6%, 47.3%
Ritvo/CAMH study:
N = ___ non responders defined by:
1)
2)
Reasons:
N = 6, defined by:
1) not remitted
2) <40% symptom reduction
Reasons: unmotivated, non-adherent, and social withdrawal
Wait list control subjects in Ritvo/CAMH study:
N = ____
N = ____ with completed measures
N = ____ dropped out after baseline (before 3 months)
N = ____ dropped out (after 3 months)
___% retention, ____% dropout
23 consented
9 with completed measures
9 dropped out after baseline
5 dropped out
39% retention, 61% dropout
What was the retention rate for intervention group in Ritvo/CAMH study?
91%, N = 20 with completed measures
True/false; in Ritvo/CAMH study, it’s likely that the control group had a high dropout rate because the subjects had an early response to effective treatment
False; 5 completed 3 month measures, and 2 were in remission but 3 were not in remission
What % of intervention group completers in Ritvo/CAMH study at 6 months?
60% (12/20 participants)
What are the mean BDI-II scores in Ritvo/CAMH study at baseline and follow up in intervention and control groups?
intervention :
29.2 BDI baseline
13.6 BDI follow up
53% mean reduction
control:
26.8 BDI baseline
19.7 BDI follow up
26% mean reduction
Aside from BDI-II, BAI, QIDS & HDRS, what 2 other scales were used in CAMH/Ritvo study?
Which study found a non-significant p-value?
BPI = Brief Pain Inventory
FFMQ: 5-Facet Mindfulness Questionnaire
HDRS had a non-significant p-value of 0.09
What was used in the online intervention against each of the BDI items in CAMH study?
web browser, video, and text content
What consisted of the 5-way multi-modal approach in CAMH/Ritvo study?
CBT workbooks
Steps exercise - fitbit monitoring
Mindfulness - relaxation practices (videos)
Text messages
Therapeutic alliance (sincere effort to help those who are down, i.e., generosity)